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Items: 1 to 20 of 86

1.

Targeting ER α-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections.

Warfield K, Alonzi DS, Hill J, Caputo A, Roversi P, Kiappes JL, Sheets N, Duchars M, Dwek R, Biggins J, Barnard DL, Shresta S, Treston A, Zitzmann N.

J Med Chem. 2020 Mar 31. doi: 10.1021/acs.jmedchem.0c00067. [Epub ahead of print]

PMID:
32227946
2.

Modulation of ERQC and ERAD: A Broad-Spectrum Spanner in the Works of Cancer Cells?

Tax G, Lia A, Santino A, Roversi P.

J Oncol. 2019 Oct 1;2019:8384913. doi: 10.1155/2019/8384913. eCollection 2019. Review.

3.

Early management of COPD: where are we now and where do we go from here? A Delphi consensus project.

Di Marco F, Balbo P, de Blasio F, Cardaci V, Crimi N, Girbino G, Pelaia G, Pirina P, Roversi P, Santus P, Scichilone N, Vatrella A, Pasqualetti P, Carone M.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 4;14:353-360. doi: 10.2147/COPD.S176662. eCollection 2019. Review.

4.

EFR-Mediated Innate Immune Response in Arabidopsis thaliana is a Useful Tool for Identification of Novel ERQC Modulators.

Lia A, Gallo A, Marti L, Roversi P, Santino A.

Genes (Basel). 2018 Dec 27;10(1). pii: E15. doi: 10.3390/genes10010015.

5.

In Planta Preliminary Screening of ER Glycoprotein Folding Quality Control (ERQC) Modulators.

Marti L, Lia A, Reca IB, Roversi P, Santino A, Zitzmann N.

Int J Mol Sci. 2018 Jul 23;19(7). pii: E2135. doi: 10.3390/ijms19072135.

6.

Structural basis of pyrrole polymerization in human porphobilinogen deaminase.

Pluta P, Roversi P, Bernardo-Seisdedos G, Rojas AL, Cooper JB, Gu S, Pickersgill RW, Millet O.

Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):1948-1955. doi: 10.1016/j.bbagen.2018.06.013. Epub 2018 Jun 15.

7.

Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II.

Caputo AT, Alonzi DS, Kiappes JL, Struwe WB, Cross A, Basu S, Darlot B, Roversi P, Zitzmann N.

Adv Exp Med Biol. 2018;1062:265-276. doi: 10.1007/978-981-10-8727-1_19. Review.

PMID:
29845539
8.

Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.

Cunha ES, Sfriso P, Rojas AL, Roversi P, Hospital A, Orozco M, Abrescia NGA.

Structure. 2018 Jan 2;26(1):181. doi: 10.1016/j.str.2017.11.015. No abstract available.

9.

Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.

Roversi P, Johnson S, Preston SG, Nunn MA, Paesen GC, Austyn JM, Nuttall PA, Lea SM.

Sci Rep. 2017 Nov 22;7(1):16057. doi: 10.1038/s41598-017-16413-2.

10.

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).

Kryshtafovych A, Albrecht R, Baslé A, Bule P, Caputo AT, Carvalho AL, Chao KL, Diskin R, Fidelis K, Fontes CMGA, Fredslund F, Gilbert HJ, Goulding CW, Hartmann MD, Hayes CS, Herzberg O, Hill JC, Joachimiak A, Kohring GW, Koning RI, Lo Leggio L, Mangiagalli M, Michalska K, Moult J, Najmudin S, Nardini M, Nardone V, Ndeh D, Nguyen TH, Pintacuda G, Postel S, van Raaij MJ, Roversi P, Shimon A, Singh AK, Sundberg EJ, Tars K, Zitzmann N, Schwede T.

Proteins. 2018 Mar;86 Suppl 1:27-50. doi: 10.1002/prot.25392. Epub 2017 Oct 16.

11.

Anharmonic motions versus dynamic disorder at the Mg ion from the charge densities in pyrope (Mg3Al2Si3O12) crystals at 30 K: six of one, half a dozen of the other.

Destro R, Ruffo R, Roversi P, Soave R, Loconte L, Lo Presti L.

Acta Crystallogr B Struct Sci Cryst Eng Mater. 2017 Aug 1;73(Pt 4):722-736. doi: 10.1107/S2052520617006102. Epub 2017 Jul 25.

12.

Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.

Roversi P, Marti L, Caputo AT, Alonzi DS, Hill JC, Dent KC, Kumar A, Levasseur MD, Lia A, Waksman T, Basu S, Soto Albrecht Y, Qian K, McIvor JP, Lipp CB, Siliqi D, Vasiljević S, Mohammed S, Lukacik P, Walsh MA, Santino A, Zitzmann N.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8544-8549. doi: 10.1073/pnas.1703682114. Epub 2017 Jul 24.

13.

Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.

Yan J, Beattie TR, Rojas AL, Schermerhorn K, Gristwood T, Trinidad JC, Albers SV, Roversi P, Gardner AF, Abrescia NGA, Bell SD.

Nat Commun. 2017 May 2;8:15075. doi: 10.1038/ncomms15075.

14.

Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.

Cunha ES, Sfriso P, Rojas AL, Roversi P, Hospital A, Orozco M, Abrescia NGA.

Structure. 2017 Jan 3;25(1):53-65. doi: 10.1016/j.str.2016.11.003. Epub 2016 Dec 1. Erratum in: Structure. 2018 Jan 2;26(1):181.

15.

Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.

Caputo AT, Alonzi DS, Marti L, Reca IB, Kiappes JL, Struwe WB, Cross A, Basu S, Lowe ED, Darlot B, Santino A, Roversi P, Zitzmann N.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4630-8. doi: 10.1073/pnas.1604463113. Epub 2016 Jul 26.

16.

Super-complexes of adhesion GPCRs and neural guidance receptors.

Jackson VA, Mehmood S, Chavent M, Roversi P, Carrasquero M, Del Toro D, Seyit-Bremer G, Ranaivoson FM, Comoletti D, Sansom MS, Robinson CV, Klein R, Seiradake E.

Nat Commun. 2016 Apr 19;7:11184. doi: 10.1038/ncomms11184.

17.

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.

Chappell P, Meziane el K, Harrison M, Magiera Ł, Hermann C, Mears L, Wrobel AG, Durant C, Nielsen LL, Buus S, Ternette N, Mwangi W, Butter C, Nair V, Ahyee T, Duggleby R, Madrigal A, Roversi P, Lea SM, Kaufman J.

Elife. 2015 Apr 10;4:e05345. doi: 10.7554/eLife.05345.

18.

Structural basis of latrophilin-FLRT interaction.

Jackson VA, del Toro D, Carrasquero M, Roversi P, Harlos K, Klein R, Seiradake E.

Structure. 2015 Apr 7;23(4):774-81. doi: 10.1016/j.str.2015.01.013. Epub 2015 Feb 26.

19.

The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects.

Neyen C, Binggeli O, Roversi P, Bertin L, Sleiman MB, Lemaitre B.

Dev Comp Immunol. 2015 Jun;50(2):166-74. doi: 10.1016/j.dci.2014.12.011. Epub 2014 Dec 24.

PMID:
25543001
20.

Pulmonary disease caused by Mycobacterium marseillense, Italy.

Grottola A, Roversi P, Fabio A, Antenora F, Apice M, Tagliazucchi S, Gennari W, Serpini GF, Rumpianesi F, Fabbri LM, Magnani R, Pecorari M.

Emerg Infect Dis. 2014 Oct;20(10):1769-70. doi: 10.3201/eid2010.140309. No abstract available.

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