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Items: 1 to 20 of 45


Pharmacological Inhibition of Class IIA HDACs by LMK-235 in Pancreatic Neuroendocrine Tumor Cells.

Wanek J, Gaisberger M, Beyreis M, Mayr C, Helm K, Primavesi F, Jäger T, Di Fazio P, Jakab M, Wagner A, Neureiter D, Kiesslich T.

Int J Mol Sci. 2018 Oct 12;19(10). pii: E3128. doi: 10.3390/ijms19103128.


Panobinostat mediated cell death: a novel therapeutic approach for osteosarcoma.

Wirries A, Jabari S, Jansen EP, Roth S, Figueroa-Juárez E, Wissniowski TT, Neureiter D, Klieser E, Lechler P, Ruchholtz S, Bartsch DK, Boese CK, Di Fazio P.

Oncotarget. 2018 Aug 31;9(68):32997-33010. doi: 10.18632/oncotarget.26038. eCollection 2018 Aug 31.


The Combination of MiRNA-196b, LCN2, and TIMP1 is a Potential Set of Circulating Biomarkers for Screening Individuals at Risk for Familial Pancreatic Cancer.

Bartsch DK, Gercke N, Strauch K, Wieboldt R, Matthäi E, Wagner V, Rospleszcz S, Schäfer A, Franke FS, Mintziras I, Bauer C, Grote T, Figiel J, Di Fazio P, Burchert A, Reinartz S, Pogge von Strandmann E, Klöppel G, Slater EP.

J Clin Med. 2018 Sep 20;7(10). pii: E295. doi: 10.3390/jcm7100295.


HDAC-Linked "Proliferative" miRNA Expression Pattern in Pancreatic Neuroendocrine Tumors.

Klieser E, Urbas R, Swierczynski S, Stättner S, Primavesi F, Jäger T, Mayr C, Kiesslich T, Fazio PD, Helm K, Neureiter D.

Int J Mol Sci. 2018 Sep 15;19(9). pii: E2781. doi: 10.3390/ijms19092781.


Targeting autophagy in liver cancer.

Di Fazio P, Matrood S.

Transl Gastroenterol Hepatol. 2018 Jul 10;3:39. doi: 10.21037/tgh.2018.06.09. eCollection 2018. Review.


Chemoprevention with Enalapril and Aspirin in Men1(+/T) Knockout Mouse Model.

Manoharan J, Fendrich V, Di Fazio P, Bollmann C, Roth S, Joos B, Mintziras I, Albers MB, Ramaswamy A, Bertolino P, Zhang CX, Slater EP, Bartsch DK, Lopez-Lopez CL.

Neuroendocrinology. 2018;107(3):257-266. doi: 10.1159/000492224. Epub 2018 Jul 19.


Selumetinib Activity in Thyroid Cancer Cells: Modulation of Sodium Iodide Symporter and Associated miRNAs.

Wächter S, Wunderlich A, Greene BH, Roth S, Elxnat M, Fellinger SA, Verburg FA, Luster M, Bartsch DK, Di Fazio P.

Int J Mol Sci. 2018 Jul 17;19(7). pii: E2077. doi: 10.3390/ijms19072077.


Effects of multi and selective targeted tyrosine kinase inhibitors on function and signaling of different bladder cancer cells.

Hänze J, Kessel F, Di Fazio P, Hofmann R, Hegele A.

Biomed Pharmacother. 2018 Oct;106:316-325. doi: 10.1016/j.biopha.2018.06.110. Epub 2018 Jul 11.


Individualised Multimodal Treatment Strategies for Anaplastic and Poorly Differentiated Thyroid Cancer.

Wächter S, Wunderlich A, Roth S, Mintziras I, Maurer E, Hoffmann S, Verburg FA, Fellinger SA, Holzer K, Bartsch DK, Di Fazio P.

J Clin Med. 2018 May 15;7(5). pii: E115. doi: 10.3390/jcm7050115.


Epigenetic Modifications in Thyroid Cancer Cells Restore NIS and Radio-Iodine Uptake and Promote Cell Death.

Wächter S, Damanakis AI, Elxnat M, Roth S, Wunderlich A, Verburg FA, Fellinger SA, Bartsch DK, Di Fazio P.

J Clin Med. 2018 Mar 21;7(4). pii: E61. doi: 10.3390/jcm7040061.


Expression of hsa-let-7b-5p, hsa-let-7f-5p, and hsa-miR-222-3p and their putative targets HMGA2 and CDKN1B in typical and atypical carcinoid tumors of the lung.

Di Fazio P, Maass M, Roth S, Meyer C, Grups J, Rexin P, Bartsch DK, Kirschbaum A.

Tumour Biol. 2017 Oct;39(10):1010428317728417. doi: 10.1177/1010428317728417.


Comprehensive immunohistochemical analysis of histone deacetylases in pancreatic neuroendocrine tumors: HDAC5 as a predictor of poor clinical outcome.

Klieser E, Urbas R, Stättner S, Primavesi F, Jäger T, Dinnewitzer A, Mayr C, Kiesslich T, Holzmann K, Di Fazio P, Neureiter D, Swierczynski S.

Hum Pathol. 2017 Jul;65:41-52. doi: 10.1016/j.humpath.2017.02.009. Epub 2017 Feb 22.


Fibromyalgia syndrome: metabolic and autophagic processes in intermittent cold stress mice.

Oezel L, Then H, Jung AL, Jabari S, Bonaterra GA, Wissniowski TT, Önel SF, Ocker M, Thieme K, Kinscherf R, Di Fazio P.

Pharmacol Res Perspect. 2016 Sep 27;4(5):e00248. eCollection 2016 Oct. Erratum in: Pharmacol Res Perspect. 2016 Nov 24;4(6):e00277.


Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer.

Di Fazio P, Waldegger P, Jabari S, Lingelbach S, Montalbano R, Ocker M, Slater EP, Bartsch DK, Illig R, Neureiter D, Wissniowski TT.

Oncotarget. 2016 May 17;7(20):28998-9010. doi: 10.18632/oncotarget.8585.


Morphological Alterations in Gastrocnemius and Soleus Muscles in Male and Female Mice in a Fibromyalgia Model.

Bonaterra GA, Then H, Oezel L, Schwarzbach H, Ocker M, Thieme K, Di Fazio P, Kinscherf R.

PLoS One. 2016 Mar 17;11(3):e0151116. doi: 10.1371/journal.pone.0151116. eCollection 2016.


Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells.

Montalbano R, Honrath B, Wissniowski TT, Elxnat M, Roth S, Ocker M, Quint K, Churin Y, Roederfeld M, Schroeder D, Glebe D, Roeb E, Di Fazio P.

Oncotarget. 2016 Apr 12;7(15):20312-23. doi: 10.18632/oncotarget.7950.


MicroRNAs let7 expression in thyroid cancer: correlation with their deputed targets HMGA2 and SLC5A5.

Damanakis AI, Eckhardt S, Wunderlich A, Roth S, Wissniowski TT, Bartsch DK, Di Fazio P.

J Cancer Res Clin Oncol. 2016 Jun;142(6):1213-20. doi: 10.1007/s00432-016-2138-z. Epub 2016 Mar 9.


Erratum to: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.

Gandesiri M, Chakilam S, Ivanovska J, Benderska N, Ocker M, Di Fazio P, Feoktistova M, Gali-Muhtasib H, Rave-Fränk M, Prante O, Christiansen H, Leverkus M, Hartmann A, Schneider-Stock R.

Apoptosis. 2016 May;21(5):671-4. doi: 10.1007/s10495-016-1224-7. No abstract available.


The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells.

Mayr C, Wagner A, Loeffelberger M, Bruckner D, Jakab M, Berr F, Di Fazio P, Ocker M, Neureiter D, Pichler M, Kiesslich T.

Oncotarget. 2016 Jan 5;7(1):745-58. doi: 10.18632/oncotarget.6378.


Endoplasmic Reticulum Stress in Pancreatic Neuroendocrine Tumors is Linked to Clinicopathological Parameters and Possible Epigenetic Regulations.

Klieser E, Illig R, Státtner S, Primavesi F, Jáger T, Swierczynski S, Kiesslich T, Kemmerling R, Bollmann C, Di Fazio P, Neureiter D.

Anticancer Res. 2015 Nov;35(11):6127-36.


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