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Items: 19


An Eye on Staphylococcus aureus Toxins: Roles in Ocular Damage and Inflammation.

Astley R, Miller FC, Mursalin MH, Coburn PS, Callegan MC.

Toxins (Basel). 2019 Jun 19;11(6). pii: E356. doi: 10.3390/toxins11060356. Review.


Targets of immunomodulation in bacterial endophthalmitis.

Miller FC, Coburn PS, Huzzatul MM, LaGrow AL, Livingston E, Callegan MC.

Prog Retin Eye Res. 2019 May 28. pii: S1350-9462(19)30027-8. doi: 10.1016/j.preteyeres.2019.05.004. [Epub ahead of print] Review.


Disarming Pore-Forming Toxins with Biomimetic Nanosponges in Intraocular Infections.

Coburn PS, Miller FC, LaGrow AL, Land C, Mursalin H, Livingston E, Amayem O, Chen Y, Gao W, Zhang L, Callegan MC.

mSphere. 2019 May 15;4(3). pii: e00262-19. doi: 10.1128/mSphere.00262-19.


TLR4 modulates inflammatory gene targets in the retina during Bacillus cereus endophthalmitis.

Coburn PS, Miller FC, LaGrow AL, Parkunan SM, Blake Randall C, Staats RL, Callegan MC.

BMC Ophthalmol. 2018 Apr 16;18(1):96. doi: 10.1186/s12886-018-0764-8.


A Novel Biomimetic Nanosponge Protects the Retina from the Enterococcus faecalis Cytolysin.

LaGrow AL, Coburn PS, Miller FC, Land C, Parkunan SM, Luk BT, Gao W, Zhang L, Callegan MC.

mSphere. 2017 Nov 22;2(6). pii: e00335-17. doi: 10.1128/mSphere.00335-17. eCollection 2017 Nov-Dec.


The role of pili in Bacillus cereus intraocular infection.

Callegan MC, Parkunan SM, Randall CB, Coburn PS, Miller FC, LaGrow AL, Astley RA, Land C, Oh SY, Schneewind O.

Exp Eye Res. 2017 Jun;159:69-76. doi: 10.1016/j.exer.2017.03.007. Epub 2017 Mar 20.


Bloodstream-To-Eye Infections Are Facilitated by Outer Blood-Retinal Barrier Dysfunction.

Coburn PS, Wiskur BJ, Miller FC, LaGrow AL, Astley RA, Elliott MH, Callegan MC.

PLoS One. 2016 May 19;11(5):e0154560. doi: 10.1371/journal.pone.0154560. eCollection 2016.


Modeling intraocular bacterial infections.

Astley RA, Coburn PS, Parkunan SM, Callegan MC.

Prog Retin Eye Res. 2016 Sep;54:30-48. doi: 10.1016/j.preteyeres.2016.04.007. Epub 2016 May 3. Review.


Blood-Retinal Barrier Compromise and Endogenous Staphylococcus aureus Endophthalmitis.

Coburn PS, Wiskur BJ, Astley RA, Callegan MC.

Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7303-11. doi: 10.1167/iovs.15-17488.


Unexpected Roles for Toll-Like Receptor 4 and TRIF in Intraocular Infection with Gram-Positive Bacteria.

Parkunan SM, Randall CB, Coburn PS, Astley RA, Staats RL, Callegan MC.

Infect Immun. 2015 Oct;83(10):3926-36. doi: 10.1128/IAI.00502-15. Epub 2015 Jul 20.


The diabetic ocular environment facilitates the development of endogenous bacterial endophthalmitis.

Coburn PS, Wiskur BJ, Christy E, Callegan MC.

Invest Ophthalmol Vis Sci. 2012 Nov 1;53(12):7426-31. doi: 10.1167/iovs.12-10661.


Transcriptional regulator PerA influences biofilm-associated, platelet binding, and metabolic gene expression in Enterococcus faecalis.

Maddox SM, Coburn PS, Shankar N, Conway T.

PLoS One. 2012;7(4):e34398. doi: 10.1371/journal.pone.0034398. Epub 2012 Apr 4.


A novel conjugative plasmid from Enterococcus faecalis E99 enhances resistance to ultraviolet radiation.

Coburn PS, Baghdayan AS, Craig N, Burroughs A, Tendolkar P, Miller K, Najar FZ, Roe BA, Shankar N.

Plasmid. 2010 Jul;64(1):18-25. doi: 10.1016/j.plasmid.2010.03.001. Epub 2010 Mar 20.


Genetic variation and evolution of the pathogenicity island of Enterococcus faecalis.

McBride SM, Coburn PS, Baghdayan AS, Willems RJ, Grande MJ, Shankar N, Gilmore MS.

J Bacteriol. 2009 May;191(10):3392-402. doi: 10.1128/JB.00031-09. Epub 2009 Mar 6.


An AraC-type transcriptional regulator encoded on the Enterococcus faecalis pathogenicity island contributes to pathogenesis and intracellular macrophage survival.

Coburn PS, Baghdayan AS, Dolan GT, Shankar N.

Infect Immun. 2008 Dec;76(12):5668-76. doi: 10.1128/IAI.00930-08. Epub 2008 Sep 29.


Horizontal transfer of virulence genes encoded on the Enterococcus faecalis pathogenicity island.

Coburn PS, Baghdayan AS, Dolan GT, Shankar N.

Mol Microbiol. 2007 Jan;63(2):530-44. Epub 2006 Dec 5.


Enterococcus faecalis senses target cells and in response expresses cytolysin.

Coburn PS, Pillar CM, Jett BD, Haas W, Gilmore MS.

Science. 2004 Dec 24;306(5705):2270-2.


The Enterococcus faecalis cytolysin: a novel toxin active against eukaryotic and prokaryotic cells.

Coburn PS, Gilmore MS.

Cell Microbiol. 2003 Oct;5(10):661-9. Review.


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