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Items: 18


EDEn-Electroceutical Design Environment: Ion Channel Tissue Expression Database with Small Molecule Modulators.

Churchill CDM, Winter P, Tuszynski JA, Levin M.

iScience. 2019 Jan 25;11:42-56. doi: 10.1016/j.isci.2018.12.003. Epub 2018 Dec 11.


A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase.

Freedman H, Winter P, Tuszynski J, Tyrrell DL, Houghton M.

J Biol Chem. 2018 Jun 22;293(25):9696-9705. doi: 10.1074/jbc.RA118.002588. Epub 2018 May 8.


Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin.

Spasevska I, Ayoub AT, Winter P, Preto J, Wong GK, Dumontet C, Tuszynski JA.

Int J Mol Sci. 2017 Aug 2;18(8). pii: E1676. doi: 10.3390/ijms18081676.


Novel Colchicine Derivatives and their Anti-cancer Activity.

Johnson L, Goping IS, Rieger A, Mane JY, Huzil T, Banerjee A, Luduena R, Hassani B, Winter P, Tuszynski JA.

Curr Top Med Chem. 2017;17(22):2538-2558. doi: 10.2174/1568026617666170104143618. Review.


Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer.

Wang W, Zhang H, Wang X, Patterson J, Winter P, Graham K, Ghosh S, Lee JC, Katsetos CD, Mackey JR, Tuszynski JA, Wong GK, Ludueña RF.

Protoplasma. 2017 May;254(3):1163-1173. doi: 10.1007/s00709-016-1060-1. Epub 2016 Dec 9.


Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents.

Minu M, Singh D, Mahaddalkar T, Lopus M, Winter P, Ayoub AT, Missiaen K, Tilli TM, Pasdar M, Tuszynski J.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):3855-61. doi: 10.1016/j.bmcl.2016.07.025. Epub 2016 Jul 9.


Screening Anti-Cancer Drugs against Tubulin using Catch-and-Release Electrospray Ionization Mass Spectrometry.

Rezaei Darestani R, Winter P, Kitova EN, Tuszynski JA, Klassen JS.

J Am Soc Mass Spectrom. 2016 May;27(5):876-85. doi: 10.1007/s13361-016-1360-x. Epub 2016 Mar 4.


Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length.

Kuban-Jankowska A, Gorska M, Tuszynski JA, Churchill CD, Winter P, Klobukowski M, Wozniak M.

Cell Physiol Biochem. 2015;36(3):1069-83. doi: 10.1159/000430280. Epub 2015 Jun 18.


Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells.

St George M, Ayoub AT, Banerjee A, Churchill CD, Winter P, Klobukowski M, Cass CE, Ludueña RF, Tuszynski JA, Damaraju S.

PLoS One. 2015 Jun 8;10(6):e0129168. doi: 10.1371/journal.pone.0129168. eCollection 2015.


Mathematical and computational modeling in biology at multiple scales.

Tuszynski JA, Winter P, White D, Tseng CY, Sahu KK, Gentile F, Spasevska I, Omar SI, Nayebi N, Churchill CD, Klobukowski M, El-Magd RM.

Theor Biol Med Model. 2014 Dec 27;11:52. doi: 10.1186/1742-4682-11-52. Review.


Experimental and computational study of the interaction of novel colchicinoids with a recombinant human αI/βI-tubulin heterodimer.

Mane JY, Semenchenko V, Perez-Pineiro R, Winter P, Wishart D, Tuszynski JA.

Chem Biol Drug Des. 2013 Jul;82(1):60-70. doi: 10.1111/cbdd.12132.


Activation of hydrogen peroxide to peroxytetradecanoic acid is responsible for potent inhibition of protein tyrosine phosphatase CD45.

Kuban-Jankowska A, Tuszynski JA, Winter P, Gorska M, Knap N, Wozniak M.

PLoS One. 2012;7(12):e52495. doi: 10.1371/journal.pone.0052495. Epub 2012 Dec 27.


Modeling the yew tree tubulin and a comparison of its interaction with paclitaxel to human tubulin.

Tuszynski JA, Craddock TJ, Mane JY, Barakat K, Tseng CY, Gajewski M, Winter P, Alisaraie L, Patterson J, Carpenter E, Wang W, Deyholos MK, Li L, Sun X, Zhang Y, Wong GK.

Pharm Res. 2012 Nov;29(11):3007-21. doi: 10.1007/s11095-012-0829-y. Epub 2012 Jul 26.


A music quality rating test battery for cochlear implant users to compare the FSP and HDCIS strategies for music appreciation.

Looi V, Winter P, Anderson I, Sucher C.

Int J Audiol. 2011 Aug;50(8):503-18. doi: 10.3109/14992027.2011.562246. Epub 2011 Jun 21.


Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives.

Tseng CY, Mane JY, Winter P, Johnson L, Huzil T, Izbicka E, Luduena RF, Tuszynski JA.

Mol Cancer. 2010 May 30;9:131. doi: 10.1186/1476-4598-9-131.


Computational design and biological testing of highly cytotoxic colchicine ring A modifications.

Torin Huzil J, Winter P, Johnson L, Weis AL, Bakos T, Banerjee A, Luduena RF, Damaraju S, Tuszynski JA.

Chem Biol Drug Des. 2010 Jun;75(6):541-50. doi: 10.1111/j.1747-0285.2010.00970.x. Epub 2010 Apr 8.


Coarse-grained molecular simulation of diffusion and reaction kinetics in a crowded virtual cytoplasm.

Ridgway D, Broderick G, Lopez-Campistrous A, Ru'aini M, Winter P, Hamilton M, Boulanger P, Kovalenko A, Ellison MJ.

Biophys J. 2008 May 15;94(10):3748-59. doi: 10.1529/biophysj.107.116053. Epub 2008 Jan 30. Erratum in: Biophys J. 2009 Mar 18;96(6):2548.


Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS.

Zhang N, Chen R, Young N, Wishart D, Winter P, Weiner JH, Li L.

Proteomics. 2007 Feb;7(4):484-493. doi: 10.1002/pmic.200600518.


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