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Items: 1 to 20 of 126

1.

Angiotensin-Converting Enzyme Related-Polymorphisms on Inflammation, Muscle and Myocardial Damage After a Marathon Race.

Sierra APR, Lima GHO, da Silva ED, Maciel JFS, Benetti MP, de Oliveira RA, Martins PFO, Kiss MAP, Ghorayeb N, Newsholme P, Pesquero JB, Cury-Boaventura MF.

Front Genet. 2019 Oct 25;10:984. doi: 10.3389/fgene.2019.00984. eCollection 2019.

2.

Nitric Oxide and Redox State Measurements in Pancreatic Beta Cells.

Carlessi R, Cruzat V, Chen Y, Newsholme P.

Methods Mol Biol. 2020;2076:241-253. doi: 10.1007/978-1-4939-9882-1_14.

PMID:
31586332
3.

Effects of vitamin D on primary human skeletal muscle cell proliferation, differentiation, protein synthesis and bioenergetics.

Romeu Montenegro K, Carlessi R, Cruzat V, Newsholme P.

J Steroid Biochem Mol Biol. 2019 Oct;193:105423. doi: 10.1016/j.jsbmb.2019.105423. Epub 2019 Jul 3.

PMID:
31279004
4.

Oxidative stress pathways in pancreatic β-cells and insulin-sensitive cells and tissues: importance to cell metabolism, function, and dysfunction.

Newsholme P, Keane KN, Carlessi R, Cruzat V.

Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C420-C433. doi: 10.1152/ajpcell.00141.2019. Epub 2019 Jun 19.

PMID:
31216193
5.

Mechanisms of vitamin D action in skeletal muscle.

Montenegro KR, Cruzat V, Carlessi R, Newsholme P.

Nutr Res Rev. 2019 Dec;32(2):192-204. doi: 10.1017/S0954422419000064. Epub 2019 Jun 17.

PMID:
31203824
6.

Glutamine deprivation induces metabolic adaptations associated with beta cell dysfunction and exacerbate lipotoxicity.

Carlessi R, Rowlands J, Ellison G, Helena de Oliveira Alves H, Newsholme P, Mamotte C.

Mol Cell Endocrinol. 2019 Jul 1;491:110433. doi: 10.1016/j.mce.2019.04.013. Epub 2019 Apr 21.

PMID:
31018148
7.

Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes.

Bridgeman S, Northrop W, Ellison G, Sabapathy T, Melton PE, Newsholme P, Mamotte CDS.

Cancers (Basel). 2019 Apr 10;11(4). pii: E516. doi: 10.3390/cancers11040516.

8.

Use of virus-like particles as a native membrane model to study the interaction of insulin with the insulin receptor.

Sabapathy T, Helmerhorst E, Bottomley S, Babaeff S, Munyard K, Newsholme P, Mamotte CD.

Biochim Biophys Acta Biomembr. 2019 Jun 1;1861(6):1204-1212. doi: 10.1016/j.bbamem.2019.03.021. Epub 2019 Apr 2.

PMID:
30951702
9.

Epigenetic demethylation of sFRPs, with emphasis on sFRP4 activation, leading to Wnt signalling suppression and histone modifications in breast, prostate, and ovary cancer stem cells.

Deshmukh A, Arfuso F, Newsholme P, Dharmarajan A.

Int J Biochem Cell Biol. 2019 Apr;109:23-32. doi: 10.1016/j.biocel.2019.01.016. Epub 2019 Jan 30.

PMID:
30710752
10.

Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 β-Cell Line: A Preclinical Model for Type 2 Diabetes.

Rowlands J, Walz N, Rowles JE, Keane KN, Carlessi R, Newsholme P.

Methods Mol Biol. 2019;1916:329-340. doi: 10.1007/978-1-4939-8994-2_32.

PMID:
30535710
11.

Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function.

Rowlands J, Heng J, Newsholme P, Carlessi R.

Front Endocrinol (Lausanne). 2018 Nov 23;9:672. doi: 10.3389/fendo.2018.00672. eCollection 2018. Review.

12.

The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people.

Krause M, Crognale D, Cogan K, Contarelli S, Egan B, Newsholme P, De Vito G.

Exp Gerontol. 2019 Jan;115:104-113. doi: 10.1016/j.exger.2018.12.004. Epub 2018 Dec 5.

PMID:
30529477
13.

The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells.

Sumayao R Jr, Newsholme P, McMorrow T.

Antioxidants (Basel). 2018 Dec 3;7(12). pii: E179. doi: 10.3390/antiox7120179. Review.

14.

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation.

Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P.

Nutrients. 2018 Oct 23;10(11). pii: E1564. doi: 10.3390/nu10111564. Review.

15.

Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells.

Tapadia M, Carlessi R, Johnson S, Utikar R, Newsholme P.

Mol Cell Endocrinol. 2019 Jan 15;480:83-96. doi: 10.1016/j.mce.2018.10.015. Epub 2018 Oct 19.

PMID:
30347229
16.

Inducible nitric oxide synthase inhibitor 1400W increases Na+ ,K+ -ATPase levels and activity and ameliorates mitochondrial dysfunction in Ctns null kidney proximal tubular epithelial cells.

Sumayao R Jr, Newsholme P, McMorrow T.

Clin Exp Pharmacol Physiol. 2018 Nov;45(11):1149-1160. doi: 10.1111/1440-1681.12998. Epub 2018 Jul 30.

PMID:
29924417
17.

Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119.

Arifin SA, Paternoster S, Carlessi R, Casari I, Ekberg JH, Maffucci T, Newsholme P, Rosenkilde MM, Falasca M.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1132-1141. doi: 10.1016/j.bbalip.2018.06.007. Epub 2018 Jun 5.

PMID:
29883799
18.

Casein Hydrolysate with Glycemic Control Properties: Evidence from Cells, Animal Models, and Humans.

Drummond E, Flynn S, Whelan H, Nongonierma AB, Holton TA, Robinson A, Egan T, Cagney G, Shields DC, Gibney ER, Newsholme P, Gaudel C, Jacquier JC, Noronha N, FitzGerald RJ, Brennan L.

J Agric Food Chem. 2018 May 2;66(17):4352-4363. doi: 10.1021/acs.jafc.7b05550. Epub 2018 Apr 24.

PMID:
29638124
19.

The Influence of Breast Tumour-Derived Factors and Wnt Antagonism on the Transformation of Adipose-Derived Mesenchymal Stem Cells into Tumour-Associated Fibroblasts.

Visweswaran M, Keane KN, Arfuso F, Dilley RJ, Newsholme P, Dharmarajan A.

Cancer Microenviron. 2018 Jun;11(1):71-84. doi: 10.1007/s12307-018-0210-8. Epub 2018 Apr 10.

20.

Role of the cell membrane interface in modulating production and uptake of Alzheimer's beta amyloid protein.

Bharadwaj P, Solomon T, Malajczuk CJ, Mancera RL, Howard M, Arrigan DWM, Newsholme P, Martins RN.

Biochim Biophys Acta Biomembr. 2018 Mar 21. pii: S0005-2736(18)30095-6. doi: 10.1016/j.bbamem.2018.03.015. [Epub ahead of print] Review.

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