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Items: 1 to 20 of 247

1.

Regulation of efferocytosis by caspase-dependent apoptotic cell death in atherosclerosis.

Tajbakhsh A, Kovanen PT, Rezaee M, Banach M, Moallem SA, Sahebkar A.

Int J Biochem Cell Biol. 2020 Mar;120:105684. doi: 10.1016/j.biocel.2020.105684. Epub 2020 Jan 3.

PMID:
31911118
2.

Ca2+ Flux: Searching for a Role in Efferocytosis of Apoptotic Cells in Atherosclerosis.

Tajbakhsh A, Kovanen PT, Rezaee M, Banach M, Sahebkar A.

J Clin Med. 2019 Nov 21;8(12). pii: E2047. doi: 10.3390/jcm8122047. Review.

3.

Statins for children with familial hypercholesterolemia.

Vuorio A, Kuoppala J, Kovanen PT, Humphries SE, Tonstad S, Wiegman A, Drogari E, Ramaswami U.

Cochrane Database Syst Rev. 2019 Nov 7;2019(11). doi: 10.1002/14651858.CD006401.pub5. Review.

PMID:
31696945
4.

Mast Cells as Potential Accelerators of Human Atherosclerosis-From Early to Late Lesions.

Kovanen PT.

Int J Mol Sci. 2019 Sep 11;20(18). pii: E4479. doi: 10.3390/ijms20184479. Review.

5.

The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion.

Banach M, Bruckert E, Descamps OS, Ellegård L, Ezhov M, Föger B, Fras Z, Kovanen PT, Latkovskis G, März W, Panagiotakos DB, Paragh G, Pella D, Pirillo A, Poli A, Reiner Ž, Silbernagel G, Viigimaa M, Vrablík M, Catapano AL.

Atheroscler Suppl. 2019 Dec;39:e1-e8. doi: 10.1016/j.atherosclerosissup.2019.08.023. Epub 2019 Aug 17. No abstract available.

6.

Resolvins: Emerging Players in Autoimmune and Inflammatory Diseases.

Abdolmaleki F, Kovanen PT, Mardani R, Gheibi-Hayat SM, Bo S, Sahebkar A.

Clin Rev Allergy Immunol. 2020 Feb;58(1):82-91. doi: 10.1007/s12016-019-08754-9. Review.

PMID:
31267470
7.

Mast cell tryptase - Marker and maker of cardiovascular diseases.

Mohajeri M, Kovanen PT, Bianconi V, Pirro M, Cicero AFG, Sahebkar A.

Pharmacol Ther. 2019 Jul;199:91-110. doi: 10.1016/j.pharmthera.2019.03.008. Epub 2019 Mar 12. Review.

PMID:
30877022
8.

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities.

Bäck M, Yurdagul A Jr, Tabas I, Öörni K, Kovanen PT.

Nat Rev Cardiol. 2019 Jul;16(7):389-406. doi: 10.1038/s41569-019-0169-2. Review.

PMID:
30846875
9.

Lipoprotein(a) as a risk factor for calcific aortic valvulopathy in heterozygous familial hypercholesterolemia.

Vuorio A, Watts GF, Kovanen PT.

Atherosclerosis. 2019 Feb;281:25-30. doi: 10.1016/j.atherosclerosis.2018.11.040. Epub 2018 Dec 7. Review.

PMID:
30616181
10.

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages.

Ruuth M, Soronen J, Kaiharju E, Merikanto K, Perttilä J, Metso J, Lee-Rueckert M, Taskinen MR, Kovanen PT, Öörni K, Olkkonen VM, Jauhiainen MS, Laurila PP.

Lipids Health Dis. 2018 Dec 13;17(1):285. doi: 10.1186/s12944-018-0930-2.

11.

Decreasing the Cholesterol Burden in Heterozygous Familial Hypercholesterolemia Children by Dietary Plant Stanol Esters.

Vuorio A, Kovanen PT.

Nutrients. 2018 Dec 1;10(12). pii: E1842. doi: 10.3390/nu10121842. Review.

12.

IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice.

Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, Chen H, He A, Sun X, Lin Y, Tang TT, Tu X, Sjöberg S, Sukhova GK, Liao YH, Conrad DH, Yu L, Kawakami T, Kovanen PT, Libby P, Shi GP.

J Clin Invest. 2018 Nov 1;128(11):5184. doi: 10.1172/JCI124107. Epub 2018 Nov 1. No abstract available.

13.

Macrophage Infiltration in the Saccular Intracranial Aneurysm Wall as a Response to Locally Lysed Erythrocytes That Promote Degeneration.

Ollikainen E, Tulamo R, Kaitainen S, Honkanen P, Lehti S, Liimatainen T, Hernesniemi J, Niemelä M, Kovanen PT, Frösen J.

J Neuropathol Exp Neurol. 2018 Oct 1;77(10):890-903. doi: 10.1093/jnen/nly068.

PMID:
30113655
14.

Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques - Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2).

Nuotio K, Ijäs P, Heikkilä HM, Koskinen SM, Saksi J, Vikatmaa P, Sorto P, Mäkitie L, Eriksson H, Kasari S, Silvennoinen H, Valanne L, Mäyränpää MI, Kovanen PT, Soinne L, Lindsberg PJ.

Ann Med. 2018 Sep;50(6):501-510. doi: 10.1080/07853890.2018.1494851. Epub 2018 Oct 1.

PMID:
30010425
15.

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.

Ruuth M, Nguyen SD, Vihervaara T, Hilvo M, Laajala TD, Kondadi PK, Gisterå A, Lähteenmäki H, Kittilä T, Huusko J, Uusitupa M, Schwab U, Savolainen MJ, Sinisalo J, Lokki ML, Nieminen MS, Jula A, Perola M, Ylä-Herttula S, Rudel L, Öörni A, Baumann M, Baruch A, Laaksonen R, Ketelhuth DFJ, Aittokallio T, Jauhiainen M, Käkelä R, Borén J, Williams KJ, Kovanen PT, Öörni K.

Eur Heart J. 2018 Jul 14;39(27):2562-2573. doi: 10.1093/eurheartj/ehy319.

16.

Triglyceride-Rich Lipoproteins as a Source of Proinflammatory Lipids in the Arterial Wall.

Öörni K, Lehti S, Sjövall P, Kovanen PT.

Curr Med Chem. 2019;26(9):1701-1710. doi: 10.2174/0929867325666180530094819. Review.

PMID:
29848270
17.

Myeloperoxidase Associates With Degenerative Remodeling and Rupture of the Saccular Intracranial Aneurysm Wall.

Ollikainen E, Tulamo R, Lehti S, Hernesniemi J, Niemelä M, Kovanen PT, Frösen J.

J Neuropathol Exp Neurol. 2018 Jun 1;77(6):461-468. doi: 10.1093/jnen/nly028.

PMID:
29718300
18.

Human mast cell neutral proteases generate modified LDL particles with increased proteoglycan binding.

Maaninka K, Nguyen SD, Mäyränpää MI, Plihtari R, Rajamäki K, Lindsberg PJ, Kovanen PT, Öörni K.

Atherosclerosis. 2018 Aug;275:390-399. doi: 10.1016/j.atherosclerosis.2018.04.016. Epub 2018 Apr 13.

PMID:
29703634
19.

Chymase released from hypoxia-activated cardiac mast cells cleaves human apoA-I at Tyr192 and compromises its cardioprotective activity.

Kareinen I, Baumann M, Nguyen SD, Maaninka K, Anisimov A, Tozuka M, Jauhiainen M, Lee-Rueckert M, Kovanen PT.

J Lipid Res. 2018 Jun;59(6):945-957. doi: 10.1194/jlr.M077503. Epub 2018 Mar 26.

20.

Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms.

Tajbakhsh A, Rezaee M, Kovanen PT, Sahebkar A.

Pharmacol Ther. 2018 Aug;188:12-25. doi: 10.1016/j.pharmthera.2018.02.003. Epub 2018 Feb 11. Review.

PMID:
29444453

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