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Items: 1 to 20 of 26


Selenoproteins in colon cancer.

Peters KM, Carlson BA, Gladyshev VN, Tsuji PA.

Free Radic Biol Med. 2018 Nov 1;127:14-25. doi: 10.1016/j.freeradbiomed.2018.05.075. Epub 2018 May 22. Review.


Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins.

Yim SH, Everley RA, Schildberg FA, Lee SG, Orsi A, Barbati ZR, Karatepe K, Fomenko DE, Tsuji PA, Luo HR, Gygi SP, Sitia R, Sharpe AH, Hatfield DL, Gladyshev VN.

Cell Rep. 2018 May 1;23(5):1387-1398. doi: 10.1016/j.celrep.2018.04.009.


Selenocysteine tRNA[Ser]Sec, the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing.

Carlson BA, Lee BJ, Tsuji PA, Copeland PR, Schweizer U, Gladyshev VN, Hatfield DL.

Methods Mol Biol. 2018;1661:43-60. doi: 10.1007/978-1-4939-7258-6_4.


Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration.

Carlson BA, Tobe R, Yefremova E, Tsuji PA, Hoffmann VJ, Schweizer U, Gladyshev VN, Hatfield DL, Conrad M.

Redox Biol. 2016 Oct;9:22-31. doi: 10.1016/j.redox.2016.05.003. Epub 2016 May 26.


Selenoprotein Gene Nomenclature.

Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, Green FR, Guigó R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, Köhrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonović M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y.

J Biol Chem. 2016 Nov 11;291(46):24036-24040. Epub 2016 Sep 19.


Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.

Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, Schweizer U, Gladyshev VN, Hatfield DL, Lee BJ.

Biochem J. 2016 Jul 15;473(14):2141-54. doi: 10.1042/BCJ20160393. Epub 2016 May 16.


Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy.

Tobe R, Carlson BA, Tsuji PA, Lee BJ, Gladyshev VN, Hatfield DL.

Cancers (Basel). 2015 Nov 10;7(4):2262-76. doi: 10.3390/cancers7040889.


Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice.

Tsuji PA, Carlson BA, Anderson CB, Seifried HE, Hatfield DL, Howard MT.

Nutrients. 2015 Aug 6;7(8):6529-49. doi: 10.3390/nu7085297.


The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways.

Tsuji PA, Carlson BA, Yoo MH, Naranjo-Suarez S, Xu XM, He Y, Asaki E, Seifried HE, Reinhold WC, Davis CD, Gladyshev VN, Hatfield DL.

PLoS One. 2015 Apr 17;10(4):e0124487. doi: 10.1371/journal.pone.0124487. eCollection 2015.


Cell Proliferation and Motility Are Inhibited by G1 Phase Arrest in 15-kDa Selenoprotein-Deficient Chang Liver Cells.

Bang J, Huh JH, Na JW, Lu Q, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ.

Mol Cells. 2015 May;38(5):457-65. doi: 10.14348/molcells.2015.0007. Epub 2015 Feb 27.


Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway.

Bang J, Jang M, Huh JH, Na JW, Shim M, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ.

Biochem Biophys Res Commun. 2015 Jan 24;456(4):884-90. doi: 10.1016/j.bbrc.2014.12.059. Epub 2014 Dec 18.


Selenium and selenocysteine: roles in cancer, health, and development.

Hatfield DL, Tsuji PA, Carlson BA, Gladyshev VN.

Trends Biochem Sci. 2014 Mar;39(3):112-20. doi: 10.1016/j.tibs.2013.12.007. Epub 2014 Jan 28. Review.


Structure-activity analysis of flavonoids: direct and indirect antioxidant, and antiinflammatory potencies and toxicities.

Tsuji PA, Stephenson KK, Wade KL, Liu H, Fahey JW.

Nutr Cancer. 2013;65(7):1014-25. doi: 10.1080/01635581.2013.809127. Epub 2013 Oct 2.


Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase status.

Naranjo-Suarez S, Carlson BA, Tobe R, Yoo MH, Tsuji PA, Gladyshev VN, Hatfield DL.

Mol Cells. 2013 Aug;36(2):151-7. doi: 10.1007/s10059-013-0121-y. Epub 2013 Aug 1.


High error rates in selenocysteine insertion in mammalian cells treated with the antibiotic doxycycline, chloramphenicol, or geneticin.

Tobe R, Naranjo-Suarez S, Everley RA, Carlson BA, Turanov AA, Tsuji PA, Yoo MH, Gygi SP, Gladyshev VN, Hatfield DL.

J Biol Chem. 2013 May 24;288(21):14709-15. doi: 10.1074/jbc.M112.446666. Epub 2013 Apr 15.


Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice.

Tsuji PA, Carlson BA, Naranjo-Suarez S, Yoo MH, Xu XM, Fomenko DE, Gladyshev VN, Hatfield DL, Davis CD.

PLoS One. 2012;7(12):e50574. doi: 10.1371/journal.pone.0050574. Epub 2012 Dec 4.


Selenoproteins and cancer prevention.

Davis CD, Tsuji PA, Milner JA.

Annu Rev Nutr. 2012 Aug 21;32:73-95. doi: 10.1146/annurev-nutr-071811-150740. Epub 2012 Mar 8. Review.


HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia.

Naranjo-Suarez S, Carlson BA, Tsuji PA, Yoo MH, Gladyshev VN, Hatfield DL.

PLoS One. 2012;7(2):e30470. doi: 10.1371/journal.pone.0030470. Epub 2012 Feb 13.


Deficiency in the 15 kDa selenoprotein inhibits human colon cancer cell growth.

Tsuji PA, Naranjo-Suarez S, Carlson BA, Tobe R, Yoo MH, Davis CD.

Nutrients. 2011 Sep;3(9):805-17. doi: 10.3390/nu3090805. Epub 2011 Sep 5.


Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice.

Kasaikina MV, Fomenko DE, Labunskyy VM, Lachke SA, Qiu W, Moncaster JA, Zhang J, Wojnarowicz MW Jr, Natarajan SK, Malinouski M, Schweizer U, Tsuji PA, Carlson BA, Maas RL, Lou MF, Goldstein LE, Hatfield DL, Gladyshev VN.

J Biol Chem. 2011 Sep 23;286(38):33203-12. doi: 10.1074/jbc.M111.259218. Epub 2011 Jul 18.

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