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Items: 1 to 20 of 135

1.

Blood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression.

Lokwani R, Wark PA, Baines KJ, Fricker M, Barker D, Simpson JL.

Int J Chron Obstruct Pulmon Dis. 2019 Nov 15;14:2517-2525. doi: 10.2147/COPD.S222486. eCollection 2019.

2.

Sputum transcriptomics implicates increased p38 signalling activity in severe asthma.

Baines KJ, Fricker M, McDonald VM, Simpson JL, Wood LG, Wark PAB, Macdonald HE, Reid A, Gibson PG.

Respirology. 2019 Dec 6. doi: 10.1111/resp.13749. [Epub ahead of print]

PMID:
31808595
3.

Targeting Treatable Traits in Severe Asthma: A Randomised Controlled Trial.

McDonald VM, Clark VL, Cordova-Rivera L, Wark PAB, Baines KJ, Gibson PG.

Eur Respir J. 2019 Dec 5. pii: 1901509. doi: 10.1183/13993003.01509-2019. [Epub ahead of print]

PMID:
31806719
4.

Nasal epithelial cells to assess in vitro immune responses to respiratory virus infection in pregnant women with asthma.

Vanders RL, Hsu A, Gibson PG, Murphy VE, Wark PAB.

Respir Res. 2019 Nov 20;20(1):259. doi: 10.1186/s12931-019-1225-5.

5.

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN).

Cheng AC, Holmes M, Dwyer DE, Senanayake S, Cooley L, Irving LB, Simpson G, Korman T, Macartney K, Friedman ND, Wark P, Howell A, Blyth CC, Crawford N, Buttery J, Bowler S, Upham JW, Waterer GW, Kotsimbos T, Kelly PM.

Commun Dis Intell (2018). 2019 Nov 18;43. doi: 10.33321/cdi.2019.43.48.

6.

Hypoxia-inducible factor and bacterial infections in chronic obstructive pulmonary disease.

Shukla SD, Walters EH, Simpson JL, Keely S, Wark PAB, O'Toole RF, Hansbro PM.

Respirology. 2019 Oct 30. doi: 10.1111/resp.13722. [Epub ahead of print] Review.

7.

Why are people with asthma more susceptible to influenza?

Wark PAB.

Eur Respir J. 2019 Oct 24;54(4). pii: 1901748. doi: 10.1183/13993003.01748-2019. Print 2019 Oct. No abstract available.

PMID:
31649149
8.

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN).

Cheng AC, Holmes M, Dwyer DE, Senanayake S, Cooley L, Irving LB, Simpson G, Korman T, Macartney K, Friedman ND, Wark P, Howell A, Blyth CC, Bowler S, Upham J, Waterer GW, Kotsimbos T, Kelly PM.

Commun Dis Intell (2018). 2019 Sep 16;43. doi: 10.33321/cdi.2019.43.39.

9.

Antiviral immunity is impaired in COPD patients with frequent exacerbations.

Singanayagam A, Loo SL, Calderazzo M, Finney LJ, Trujillo Torralbo MB, Bakhsoliani E, Girkin J, Veerati P, Pathinayake PS, Nichol KS, Reid A, Footitt J, Wark PAB, Grainge CL, Johnston SL, Bartlett NW, Mallia P.

Am J Physiol Lung Cell Mol Physiol. 2019 Dec 1;317(6):L893-L903. doi: 10.1152/ajplung.00253.2019. Epub 2019 Sep 12.

10.

Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.

Liu G, Cooley MA, Jarnicki AG, Borghuis T, Nair PM, Tjin G, Hsu AC, Haw TJ, Fricker M, Harrison CL, Jones B, Hansbro NG, Wark PA, Horvat JC, Argraves WS, Oliver BG, Knight DA, Burgess JK, Hansbro PM.

JCI Insight. 2019 Jul 25;5. pii: 124529. doi: 10.1172/jci.insight.124529.

11.

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses.

Hayman TJ, Hsu AC, Kolesnik TB, Dagley LF, Willemsen J, Tate MD, Baker PJ, Kershaw NJ, Kedzierski L, Webb AI, Wark PA, Kedzierska K, Masters SL, Belz GT, Binder M, Hansbro PM, Nicola NA, Nicholson SE.

Immunol Cell Biol. 2019 Oct;97(9):840-852. doi: 10.1111/imcb.12284. Epub 2019 Aug 19.

PMID:
31335993
12.

Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production.

Hu M, Schulze KE, Ghildyal R, Henstridge DC, Kolanowski JL, New EJ, Hong Y, Hsu AC, Hansbro PM, Wark PA, Bogoyevitch MA, Jans DA.

Elife. 2019 Jun 27;8. pii: e42448. doi: 10.7554/eLife.42448.

13.

Lumacaftor/ Ivacaftor improves exercise tolerance in patients with Cystic Fibrosis and severe airflow obstruction.

Wark PAB, Cookson K, Thiruchelvam T, Brannan J, Dorahy DJ.

BMC Pulm Med. 2019 Jun 17;19(1):106. doi: 10.1186/s12890-019-0866-y.

14.

IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.

Starkey MR, Plank MW, Casolari P, Papi A, Pavlidis S, Guo Y, Cameron GJM, Haw TJ, Tam A, Obiedat M, Donovan C, Hansbro NG, Nguyen DH, Nair PM, Kim RY, Horvat JC, Kaiko GE, Durum SK, Wark PA, Sin DD, Caramori G, Adcock IM, Foster PS, Hansbro PM.

Eur Respir J. 2019 Jul 18;54(1). pii: 1800174. doi: 10.1183/13993003.00174-2018. Print 2019 Jul.

PMID:
31196943
15.

Controlled Trial of Budesonide-Formoterol as Needed for Mild Asthma.

Beasley R, Holliday M, Reddel HK, Braithwaite I, Ebmeier S, Hancox RJ, Harrison T, Houghton C, Oldfield K, Papi A, Pavord ID, Williams M, Weatherall M; Novel START Study Team.

N Engl J Med. 2019 May 23;380(21):2020-2030. doi: 10.1056/NEJMoa1901963. Epub 2019 May 19.

PMID:
31112386
16.

Benralizumab for the Prevention of COPD Exacerbations.

Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators.

N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20.

PMID:
31112385
17.

Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome.

Liu G, Mateer SW, Hsu A, Goggins BJ, Tay H, Mathe A, Fan K, Neal R, Bruce J, Burns G, Minahan K, Maltby S, Fricker M, Foster PS, Wark PAB, Hansbro PM, Keely S.

Mucosal Immunol. 2019 Jul;12(4):862-873. doi: 10.1038/s41385-019-0163-3. Epub 2019 Apr 11.

PMID:
30976089
18.

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report.

McDonald VM, Fingleton J, Agusti A, Hiles SA, Clark VL, Holland AE, Marks GB, Bardin PP, Beasley R, Pavord ID, Wark PAB, Gibson PG; participants of the Treatable Traits Down Under International Workshop; Treatable Traits Down Under International Workshop participants:.

Eur Respir J. 2019 May 9;53(5). pii: 1802058. doi: 10.1183/13993003.02058-2018. Print 2019 May. Review.

PMID:
30846468
19.

Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study.

Lokwani R, Wark PAB, Baines KJ, Barker D, Simpson JL.

BMJ Open. 2019 Jan 28;9(1):e024330. doi: 10.1136/bmjopen-2018-024330.

20.

Mechanisms and Management of Asthma Exacerbations.

Ramsahai JM, Hansbro PM, Wark PAB.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):423-432. doi: 10.1164/rccm.201810-1931CI.

PMID:
30562041

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