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Items: 1 to 20 of 65

1.

Plasticiser-Free 3D Printed Hydrophilic Matrices: Quantitative 3D Surface Texture, Mechanical, Swelling, Erosion, Drug Release and Pharmacokinetic Studies.

Khizer Z, Akram MR, Sarfraz RM, Nirwan JS, Farhaj S, Yousaf M, Hussain T, Lou S, Timmins P, Conway BR, Ghori MU.

Polymers (Basel). 2019 Jun 28;11(7). pii: E1095. doi: 10.3390/polym11071095.

2.

Trends in global prescribing of antidiabetic medicines in primary care: A systematic review of literature between 2000-2018.

Ramzan S, Timmins P, Hasan SS, Babar ZU.

Prim Care Diabetes. 2019 Jun 15. pii: S1751-9918(19)30130-5. doi: 10.1016/j.pcd.2019.05.009. [Epub ahead of print] Review.

PMID:
31213359
3.

Industry update: the latest developments in the field of therapeutic delivery, 1-31 December 2018.

Timmins P.

Ther Deliv. 2019 Apr;10(4):215-226. doi: 10.4155/tde-2019-0003.

PMID:
30991919
4.

Effect of preparation method on the surface properties and UV imaging of indomethacin solid dispersions.

Asare-Addo K, Alshafiee M, Walton K, Ward A, Totea AM, Taheri S, Mawla N, Adebisi AO, Elawad S, Diza C, Timmins P, Conway BR.

Eur J Pharm Biopharm. 2019 Apr;137:148-163. doi: 10.1016/j.ejpb.2019.03.002. Epub 2019 Mar 2.

PMID:
30836178
5.

Direct imaging of the dissolution of salt forms of a carboxylic acid drug.

Asare-Addo K, Walton K, Ward A, Totea AM, Taheri S, Alshafiee M, Mawla N, Bondi A, Evans W, Adebisi A, Conway BR, Timmins P.

Int J Pharm. 2018 Nov 15;551(1-2):290-299. doi: 10.1016/j.ijpharm.2018.09.048. Epub 2018 Sep 20.

PMID:
30243943
6.

Cost analysis of type 2 diabetes mellitus treatment in economically developed countries.

Ramzan S, Timmins P, Hasan SS, Babar ZU.

Expert Rev Pharmacoecon Outcomes Res. 2019 Feb;19(1):5-14. doi: 10.1080/14737167.2018.1513790. Epub 2018 Sep 4. Review.

PMID:
30146917
7.

From 'fixed dose combinations' to 'a dynamic dose combiner': 3D printed bi-layer antihypertensive tablets.

Sadia M, Isreb A, Abbadi I, Isreb M, Aziz D, Selo A, Timmins P, Alhnan MA.

Eur J Pharm Sci. 2018 Oct 15;123:484-494. doi: 10.1016/j.ejps.2018.07.045. Epub 2018 Jul 21.

PMID:
30041029
8.

On demand manufacturing of patient-specific liquid capsules via co-ordinated 3D printing and liquid dispensing.

Okwuosa TC, Soares C, Gollwitzer V, Habashy R, Timmins P, Alhnan MA.

Eur J Pharm Sci. 2018 Jun 15;118:134-143. doi: 10.1016/j.ejps.2018.03.010. Epub 2018 Mar 11.

PMID:
29540300
9.

Monitoring of multiple solvent induced form changes during high shear wet granulation and drying processes using online Raman spectroscopy.

Reddy JP, Jones JW, Wray PS, Dennis AB, Brown J, Timmins P.

Int J Pharm. 2018 Apr 25;541(1-2):253-260. doi: 10.1016/j.ijpharm.2018.02.021. Epub 2018 Feb 24.

PMID:
29481947
10.

Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir.

Meanwell NA, Krystal MR, Nowicka-Sans B, Langley DR, Conlon DA, Eastgate MD, Grasela DM, Timmins P, Wang T, Kadow JF.

J Med Chem. 2018 Jan 11;61(1):62-80. doi: 10.1021/acs.jmedchem.7b01337. Epub 2017 Dec 22.

PMID:
29271653
11.

Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA.

Hyde EI, Callow P, Rajasekar KV, Timmins P, Patel TR, Siligardi G, Hussain R, White SA, Thomas CM, Scott DJ.

Biochem J. 2017 Aug 30;474(18):3121-3135. doi: 10.1042/BCJ20170281.

12.

Extended release of flurbiprofen from tromethamine-buffered HPMC hydrophilic matrix tablets.

Pygall S, Kujawinski S, Timmins P, Melia C.

Pharm Dev Technol. 2018 Nov;23(9):874-881. doi: 10.1080/10837450.2017.1301470. Epub 2017 Mar 16.

PMID:
28298171
13.

Characterization of Phase Separation Propensity for Amorphous Spray Dried Dispersions.

McNamara D, Yin S, Pan D, Crull G, Timmins P, Vig B.

Mol Pharm. 2017 Feb 6;14(2):377-385. doi: 10.1021/acs.molpharmaceut.6b00722. Epub 2017 Jan 20.

PMID:
28068097
14.

Understanding the Impact of Chemical Variability and Calibration Algorithms on Prediction of Solid Fraction of Roller Compacted Ribbons Using Near-Infrared (NIR) Spectroscopy.

Talwar S, Nunes C, Stevens T, Nesarikar V, Timmins P, Anderson CA, Drennen JK 3rd.

Appl Spectrosc. 2017 Jun;71(6):1209-1221. doi: 10.1177/0003702816671960. Epub 2016 Nov 4.

PMID:
27815436
15.

Advances in mechanistic understanding of release rate control mechanisms of extended-release hydrophilic matrix tablets.

Timmins P, Desai D, Chen W, Wray P, Brown J, Hanley S.

Ther Deliv. 2016 Aug;7(8):553-72. doi: 10.4155/tde-2016-0026.

PMID:
27444495
16.

Application of X-ray microtomography for the characterisation of hollow polymer-stabilised spray dried amorphous dispersion particles.

Gamble JF, Terada M, Holzner C, Lavery L, Nicholson SJ, Timmins P, Tobyn M.

Int J Pharm. 2016 Aug 20;510(1):1-8. doi: 10.1016/j.ijpharm.2016.05.051. Epub 2016 Jun 1.

PMID:
27262271
17.

Mitigation of Adverse Clinical Events of a Narrow Target Therapeutic Index Compound through Modified Release Formulation Design: An in Vitro, in Vivo, in Silico, and Clinical Pharmacokinetic Analysis.

Good DJ, Hartley R, Mathias N, Crison J, Tirucherai G, Timmins P, Hussain M, Haddadin R, Koo O, Nikfar F, Fung NK.

Mol Pharm. 2015 Dec 7;12(12):4434-44. doi: 10.1021/acs.molpharmaceut.5b00624. Epub 2015 Nov 4.

PMID:
26536519
18.

Industry update: 1-30 April 2015.

Timmins P.

Ther Deliv. 2015;6(8):903-10. doi: 10.4155/TDE.15.49. Epub 2015 Aug 14. No abstract available.

PMID:
26272086
19.

Wetting effects versus ion pairs diffusivity: interactions of anionic surfactants with highly soluble cationic drugs and its impact on tablet dissolution.

Desai D, Wong B, Huang Y, Ye Q, Guo H, Huang M, Timmins P.

J Pharm Sci. 2015 Jul;104(7):2255-65. doi: 10.1002/jps.24478. Epub 2015 May 27.

PMID:
26017286
20.

Enabled clinical use of an HIV-1 attachment inhibitor through drug delivery.

Timmins P, Brown J, Meanwell NA, Hanna GJ, Zhu L, Kadow JF.

Drug Discov Today. 2014 Sep;19(9):1288-93. doi: 10.1016/j.drudis.2014.03.025. Epub 2014 Apr 13.

PMID:
24727410

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