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Items: 14


Type I-like behavior of the type II α7 nicotinic acetylcholine receptor positive allosteric modulator A-867744.

Pesti K, Lukacs P, Mike A.

PeerJ. 2019 Sep 2;7:e7542. doi: 10.7717/peerj.7542. eCollection 2019.


Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog.

Lukacs P, Földi MC, Valánszki L, Casanova E, Biri-Kovács B, Nyitray L, Málnási-Csizmadia A, Mike A.

Sci Rep. 2018 May 25;8(1):8110. doi: 10.1038/s41598-018-26444-y.


Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures.

Cervenka R, Lukacs P, Gawali VS, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Sandtner W, Stary-Weinzinger A, Todt H.

Sci Rep. 2018 Jan 12;8(1):631. doi: 10.1038/s41598-017-18919-1.


Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels.

Gawali VS, Lukacs P, Cervenka R, Koenig X, Rubi L, Hilber K, Sandtner W, Todt H.

Mol Pharmacol. 2015 Nov;88(5):866-79. doi: 10.1124/mol.115.099580. Epub 2015 Sep 10.


Exploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.

Lukacs P, Gawali VS, Cervenka R, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Stary-Weinzinger A, Todt H.

J Biol Chem. 2014 Aug 1;289(31):21770-81. doi: 10.1074/jbc.M113.541763. Epub 2014 Jun 19.


Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

Koenig X, Rubi L, Obermair GJ, Cervenka R, Dang XB, Lukacs P, Kummer S, Bittner RE, Kubista H, Todt H, Hilber K.

Am J Physiol Heart Circ Physiol. 2014 Feb 15;306(4):H564-H573. doi: 10.1152/ajpheart.00441.2013. Epub 2013 Dec 13.


Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: a study to assess the drug's cardiac ion channel profile.

Koenig X, Kovar M, Rubi L, Mike AK, Lukacs P, Gawali VS, Todt H, Hilber K, Sandtner W.

Toxicol Appl Pharmacol. 2013 Dec 1;273(2):259-68. doi: 10.1016/j.taap.2013.05.012. Epub 2013 May 22.


Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.

Koenig X, Dysek S, Kimbacher S, Mike AK, Cervenka R, Lukacs P, Nagl K, Dang XB, Todt H, Bittner RE, Hilber K.

PLoS One. 2011;6(5):e20300. doi: 10.1371/journal.pone.0020300. Epub 2011 May 23.


Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study.

Lenkey N, Karoly R, Lukacs P, Vizi ES, Sunesen M, Fodor L, Mike A.

PLoS One. 2010 Dec 20;5(12):e15568. doi: 10.1371/journal.pone.0015568.


A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel.

Zarrabi T, Cervenka R, Sandtner W, Lukacs P, Koenig X, Hilber K, Mille M, Lipkind GM, Fozzard HA, Todt H.

J Biol Chem. 2010 Dec 10;285(50):39458-70. doi: 10.1074/jbc.M110.132886. Epub 2010 Oct 6.


The enigmatic drug binding site for sodium channel inhibitors.

Mike A, Lukacs P.

Curr Mol Pharmacol. 2010 Nov;3(3):129-44. Review.


The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.

Cervenka R, Zarrabi T, Lukacs P, Todt H.

Mar Drugs. 2010 Apr 21;8(4):1373-93. doi: 10.3390/md8041373. Review.


[Various aspects of dental prevention in the elderly].

Madléna M, Faragó R, Lukács P.

Fogorv Sz. 2007 Dec;100(6):289-93. Hungarian.


[Molecular epidemiology of cancers and precancerous conditions].

Ember I, Kiss I, Sándor J, Varga C, Gyöngyi Z, Németh K, Fehér K, Lukács P, Dombi Z.

Orv Hetil. 2004 Mar 7;145(10):507-14. Review. Hungarian.


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