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Items: 1 to 20 of 22

1.

AMPK Signaling Regulates Expression of Urea Cycle Enzymes in Response to Changes in Dietary Protein Intake.

Heibel SK, McGuire PJ, Haskins N, Majumdar HD, Rayavarapu S, Nagaraju K, Hathout Y, Brown K, Tuchman M, Caldovic L.

J Inherit Metab Dis. 2019 Jun 8. doi: 10.1002/jimd.12133. [Epub ahead of print]

PMID:
31177541
2.

Mitochondrial Dysfunction and the Aging Immune System.

McGuire PJ.

Biology (Basel). 2019 May 11;8(2). pii: E26. doi: 10.3390/biology8020026. Review.

3.

Macrophage derived TNFα promotes hepatic reprogramming to Warburg-like metabolism.

Tarasenko TN, Jestin M, Matsumoto S, Saito K, Hwang S, Gavrilova O, Trivedi N, Zerfas PM, Barca E, DiMauro S, Senac J, Venditti CP, Cherukuri M, McGuire PJ.

J Mol Med (Berl). 2019 May 3. doi: 10.1007/s00109-019-01786-w. [Epub ahead of print]

PMID:
31053970
4.

Vulnerability of pediatric patients with mitochondrial disease to vaccine-preventable diseases.

Kruk SK, Pacheco SE, Koenig MK, Bergerson JRE, Gordon-Lipkin E, McGuire PJ.

J Allergy Clin Immunol Pract. 2019 Apr 5. pii: S2213-2198(19)30332-0. doi: 10.1016/j.jaip.2019.03.046. [Epub ahead of print] No abstract available.

PMID:
30954647
5.

Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation.

Raud B, Roy DG, Divakaruni AS, Tarasenko TN, Franke R, Ma EH, Samborska B, Hsieh WY, Wong AH, Stüve P, Arnold-Schrauf C, Guderian M, Lochner M, Rampertaap S, Romito K, Monsale J, Brönstrup M, Bensinger SJ, Murphy AN, McGuire PJ, Jones RG, Sparwasser T, Berod L.

Cell Metab. 2018 Sep 4;28(3):504-515.e7. doi: 10.1016/j.cmet.2018.06.002. Epub 2018 Jun 28.

PMID:
30043753
6.

Tissue acylcarnitine status in a mouse model of mitochondrial β-oxidation deficiency during metabolic decompensation due to influenza virus infection.

Tarasenko TN, Cusmano-Ozog K, McGuire PJ.

Mol Genet Metab. 2018 Sep;125(1-2):144-152. doi: 10.1016/j.ymgme.2018.06.012. Epub 2018 Jun 23.

7.

Fatty acid metabolism in CD8+ T cell memory: Challenging current concepts.

Raud B, McGuire PJ, Jones RG, Sparwasser T, Berod L.

Immunol Rev. 2018 May;283(1):213-231. doi: 10.1111/imr.12655. Review.

PMID:
29664569
8.

The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism.

Kapnick SM, Pacheco SE, McGuire PJ.

Metabolism. 2018 Apr;81:97-112. doi: 10.1016/j.metabol.2017.11.010. Epub 2017 Nov 21. Review.

9.

The liver is a metabolic and immunologic organ: A reconsideration of metabolic decompensation due to infection in inborn errors of metabolism (IEM).

Tarasenko TN, McGuire PJ.

Mol Genet Metab. 2017 Aug;121(4):283-288. doi: 10.1016/j.ymgme.2017.06.010. Epub 2017 Jun 24. Review.

10.

Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation.

Tarasenko TN, Pacheco SE, Koenig MK, Gomez-Rodriguez J, Kapnick SM, Diaz F, Zerfas PM, Barca E, Sudderth J, DeBerardinis RJ, Covian R, Balaban RS, DiMauro S, McGuire PJ.

Cell Metab. 2017 Jun 6;25(6):1254-1268.e7. doi: 10.1016/j.cmet.2017.05.007.

11.

Sensitivity to Restimulation-Induced Cell Death Is Linked to Glycolytic Metabolism in Human T Cells.

Larsen SE, Bilenkin A, Tarasenko TN, Arjunaraja S, Stinson JR, McGuire PJ, Snow AL.

J Immunol. 2017 Jan 1;198(1):147-155. Epub 2016 Nov 16.

12.

Neutralizing Antibodies Against Adeno-Associated Viral Capsids in Patients with mut Methylmalonic Acidemia.

Harrington EA, Sloan JL, Manoli I, Chandler RJ, Schneider M, McGuire PJ, Calcedo R, Wilson JM, Venditti CP.

Hum Gene Ther. 2016 May;27(5):345-53. doi: 10.1089/hum.2015.092. Epub 2016 Mar 22.

13.

Kupffer cells modulate hepatic fatty acid oxidation during infection with PR8 influenza.

Tarasenko TN, Singh LN, Chatterji-Len M, Zerfas PM, Cusmano-Ozog K, McGuire PJ.

Biochim Biophys Acta. 2015 Nov;1852(11):2391-401. doi: 10.1016/j.bbadis.2015.08.021. Epub 2015 Aug 28.

14.

Computational modeling to predict nitrogen balance during acute metabolic decompensation in patients with urea cycle disorders.

MacLeod EL, Hall KD, McGuire PJ.

J Inherit Metab Dis. 2016 Jan;39(1):17-24. doi: 10.1007/s10545-015-9882-0. Epub 2015 Aug 11.

15.

Child Neurology: medium-chain acyl-coenzyme A dehydrogenase deficiency.

Gartner V, McGuire PJ, Lee PR.

Neurology. 2015 Jul 28;85(4):e37-40. doi: 10.1212/WNL.0000000000001786. No abstract available.

16.

A new mouse model of mild ornithine transcarbamylase deficiency (spf-j) displays cerebral amino acid perturbations at baseline and upon systemic immune activation.

Tarasenko TN, Rosas OR, Singh LN, Kristaponis K, Vernon H, McGuire PJ.

PLoS One. 2015 Feb 3;10(2):e0116594. doi: 10.1371/journal.pone.0116594. eCollection 2015.

17.

Impaired T cell function in argininosuccinate synthetase deficiency.

Tarasenko TN, Gomez-Rodriguez J, McGuire PJ.

J Leukoc Biol. 2015 Feb;97(2):273-8. doi: 10.1189/jlb.1AB0714-365R. Epub 2014 Dec 9.

18.

A longitudinal study of urea cycle disorders.

Batshaw ML, Tuchman M, Summar M, Seminara J; Members of the Urea Cycle Disorders Consortium.

Mol Genet Metab. 2014 Sep-Oct;113(1-2):127-30. doi: 10.1016/j.ymgme.2014.08.001. Epub 2014 Aug 10. Review.

19.

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.

Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y.

Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014.

20.

Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency.

McGuire PJ, Tarasenko TN, Wang T, Levy E, Zerfas PM, Moran T, Lee HS, Bequette BJ, Diaz GA.

Dis Model Mech. 2014 Feb;7(2):205-13. doi: 10.1242/dmm.013003. Epub 2013 Nov 21.

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