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Mar Drugs. 2009 Apr 17;7(2):97-112. doi: 10.3390/md7020097.

Broad-spectrum antimicrobial epiphytic and endophytic fungi from marine organisms: isolation, bioassay and taxonomy.

Author information

1
Department of Biotechnology, School of Environmental and Chemical Engineering, Dalian Jiaotong University, Dalian 116028, P.R. China. zhangyi@djtu.edu.cn

Abstract

In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were characterized to be Penicillium glabrum, Fusarium oxysporum, and Alternaria alternata.

KEYWORDS:

Epi- and endophytic; antimicrobial activity; marine derived fungi; taxonomy

PMID:
19597575
PMCID:
PMC2707037
DOI:
10.3390/md7020097
[Indexed for MEDLINE]
Free PMC Article

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