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Bioinformatics. 2008 Dec 1;24(23):2773-5. doi: 10.1093/bioinformatics/btn517. Epub 2008 Oct 7.

CNVDetector: locating copy number variations using array CGH data.

Author information

1
Department of Computer Science and Information Engineering, Graduate Institute of Biomedical Electronics and Bioinformatics and Graduate Institute of Networking and Multimedia, National Taiwan University, Taipei, Taiwan.

Abstract

CNVDetector is a program for locating copy number variations (CNVs) in a single genome. CNVDetector has several merits: (i) it can deal with the array comparative genomic hybridization data even if the noise is not normally distributed; (ii) it has a linear time kernel; (iii) its parameters can be easily selected; (iv) it evaluates the statistical significance for each CNV calling.

AVAILABILITY:

CNVDetector (for Windows platform) can be downloaded from http:www.csie.ntu.edu.tw/~kmchao/tools/CNVDetector/. The manual of CNVDetector is also available.

PMID:
18842603
DOI:
10.1093/bioinformatics/btn517
[Indexed for MEDLINE]

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