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Items: 6

1.

The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance.

Chan PC, Liao MT, Hsieh PS.

Int J Mol Sci. 2019 Jun 26;20(13). pii: E3115. doi: 10.3390/ijms20133115. Review.

2.

Importance of PLC-Dependent PI3K/AKT and AMPK Signaling in RANTES/CCR5 Mediated Macrophage Chemotaxis.

Chien HC, Chan PC, Tu CC, Day YJ, Hung LM, Juan CC, Tian YF, Hsieh PS.

Chin J Physiol. 2018 Oct 31;61(5):266-279. doi: 10.4077/CJP.2018.BAG584.

PMID:
30384400
3.

Targetted inhibition of CD74 attenuates adipose COX-2-MIF-mediated M1 macrophage polarization and retards obesity-related adipose tissue inflammation and insulin resistance.

Chan PC, Wu TN, Chen YC, Lu CH, Wabitsch M, Tian YF, Hsieh PS.

Clin Sci (Lond). 2018 Jul 31;132(14):1581-1596. doi: 10.1042/CS20180041. Print 2018 Jul 31.

PMID:
29773671
4.

Importance of NADPH oxidase-mediated redox signaling in the detrimental effect of CRP on pancreatic insulin secretion.

Chan PC, Wang YC, Chen YL, Hsu WN, Tian YF, Hsieh PS.

Free Radic Biol Med. 2017 Nov;112:200-211. doi: 10.1016/j.freeradbiomed.2017.07.032. Epub 2017 Aug 1.

PMID:
28778482
5.

Importance of adipocyte cyclooxygenase-2 and prostaglandin E2-prostaglandin E receptor 3 signaling in the development of obesity-induced adipose tissue inflammation and insulin resistance.

Chan PC, Hsiao FC, Chang HM, Wabitsch M, Hsieh PS.

FASEB J. 2016 Jun;30(6):2282-97. doi: 10.1096/fj.201500127. Epub 2016 Mar 1.

PMID:
26932930
6.

COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver.

Hsieh PS, Jin JS, Chiang CF, Chan PC, Chen CH, Shih KC.

Obesity (Silver Spring). 2009 Jun;17(6):1150-7. doi: 10.1038/oby.2008.674. Epub 2009 Feb 26.

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