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Items: 12


T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

Arbore G, West EE, Spolski R, Robertson AAB, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C.

Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210.


An optimized, fast-to-perform mouse lung infection model with the human pathogen Chlamydia trachomatis for in vivo screening of antibiotics, vaccine candidates and modified host-pathogen interactions.

Dutow P, Wask L, Bothe M, Fehlhaber B, Laudeley R, Rheinheimer C, Yang Z, Zhong G, Glage S, Klos A.

Pathog Dis. 2016 Mar;74(2). pii: ftv120. doi: 10.1093/femspd/ftv120. Epub 2015 Dec 15.


Temperature and host cell-dependent changes in virulence of Chlamydia pneumoniae CWL029 in an optimized mouse infection model.

Janik K, Bode J, Dutow P, Laudeley R, Geffers R, Sommer K, Glage S, Klos A.

Pathog Dis. 2015 Feb;73(1):1-8. doi: 10.1093/femspd/ftu001. Epub 2014 Dec 4.


DXD motif-dependent and -independent effects of the chlamydia trachomatis cytotoxin CT166.

Bothe M, Dutow P, Pich A, Genth H, Klos A.

Toxins (Basel). 2015 Feb 17;7(2):621-37. doi: 10.3390/toxins7020621.


Chlamydia psittaci: new insights into genomic diversity, clinical pathology, host-pathogen interaction and anti-bacterial immunity.

Knittler MR, Berndt A, Böcker S, Dutow P, Hänel F, Heuer D, Kägebein D, Klos A, Koch S, Liebler-Tenorio E, Ostermann C, Reinhold P, Saluz HP, Schöfl G, Sehnert P, Sachse K.

Int J Med Microbiol. 2014 Oct;304(7):877-93. doi: 10.1016/j.ijmm.2014.06.010. Epub 2014 Jun 28. Review.


Complement factor C5 but not C3 contributes significantly to hydrosalpinx development in mice infected with Chlamydia muridarum.

Yang Z, Conrad T, Zhou Z, Chen J, Dutow P, Klos A, Zhong G.

Infect Immun. 2014 Aug;82(8):3154-63. doi: 10.1128/IAI.01833-14. Epub 2014 May 19.


Role of capsule and suilysin in mucosal infection of complement-deficient mice with Streptococcus suis.

Seitz M, Beineke A, Singpiel A, Willenborg J, Dutow P, Goethe R, Valentin-Weigand P, Klos A, Baums CG.

Infect Immun. 2014 Jun;82(6):2460-71. doi: 10.1128/IAI.00080-14. Epub 2014 Mar 31.


The complement C3a receptor is critical in defense against Chlamydia psittaci in mouse lung infection and required for antibody and optimal T cell response.

Dutow P, Fehlhaber B, Bode J, Laudeley R, Rheinheimer C, Glage S, Wetsel RA, Pabst O, Klos A.

J Infect Dis. 2014 Apr 15;209(8):1269-78. doi: 10.1093/infdis/jit640. Epub 2013 Nov 23.


Severity of allergic airway disease due to house dust mite allergen is not increased after clinical recovery of lung infection with Chlamydia pneumoniae in mice.

Dutow P, Lingner S, Laudeley R, Glage S, Hoymann HG, Dittrich AM, Fehlhaber B, Müller M, Braun A, Klos A.

Infect Immun. 2013 Sep;81(9):3366-74. doi: 10.1128/IAI.00334-13. Epub 2013 Jul 1.


A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci.

Bode J, Dutow P, Sommer K, Janik K, Glage S, Tümmler B, Munder A, Laudeley R, Sachse KW, Klos A.

PLoS One. 2012;7(11):e50327. doi: 10.1371/journal.pone.0050327. Epub 2012 Nov 26.


Interactions between glycolytic enzymes of Mycoplasma pneumoniae.

Dutow P, Schmidl SR, Ridderbusch M, Stülke J.

J Mol Microbiol Biotechnol. 2010;19(3):134-9. doi: 10.1159/000321499. Epub 2010 Oct 6.


Features critical for membrane binding revealed by DivIVA crystal structure.

Oliva MA, Halbedel S, Freund SM, Dutow P, Leonard TA, Veprintsev DB, Hamoen LW, Löwe J.

EMBO J. 2010 Jun 16;29(12):1988-2001. doi: 10.1038/emboj.2010.99. Epub 2010 May 25.

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