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Items: 1 to 20 of 39

1.

Myocardial Injury After Noncardiac Surgery: Incidence, Predictive Factors, and Outcome in High-Risk Patients Undergoing Thoracic Surgery: An Observational Study.

González-Tallada A, Borrell-Vega J, Coronado C, Morales P, de Miguel M, Ferreira-González I, de Nadal M.

J Cardiothorac Vasc Anesth. 2019 Aug 16. pii: S1053-0770(19)30879-1. doi: 10.1053/j.jvca.2019.08.014. [Epub ahead of print]

PMID:
31515189
2.

Antitumor Cannabinoid Chemotypes: Structural Insights.

Morales P, Jagerovic N.

Front Pharmacol. 2019 May 31;10:621. doi: 10.3389/fphar.2019.00621. eCollection 2019.

3.

Potential metabolic and behavioural roles of the putative endocannabinoid receptors GPR18, GPR55 and GPR119 in feeding.

Ramírez-Orozco RE, García-Ruiz R, Morales P, Villalón CM, Villafán-Bernal JR, Marichal-Cancino BA.

Curr Neuropharmacol. 2019 Jan 18. doi: 10.2174/1570159X17666190118143014. [Epub ahead of print]

PMID:
31146657
4.

CBD: A New Hope?

Morales P, Reggio PH.

ACS Med Chem Lett. 2019 Apr 29;10(5):694-695. doi: 10.1021/acsmedchemlett.9b00127. eCollection 2019 May 9.

PMID:
31097982
5.

Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity.

Sotudeh N, Morales P, Hurst DP, Lynch DL, Reggio PH.

Int J Mol Sci. 2019 May 9;20(9). pii: E2300. doi: 10.3390/ijms20092300.

6.

Structural Insights into CB1 Receptor Biased Signaling.

Al-Zoubi R, Morales P, Reggio PH.

Int J Mol Sci. 2019 Apr 13;20(8). pii: E1837. doi: 10.3390/ijms20081837. Review.

7.

A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters.

Zárate SG, Morales P, Świderek K, Bolanos-Garcia VM, Bastida A.

Antibiotics (Basel). 2019 Mar 15;8(1). pii: E25. doi: 10.3390/antibiotics8010025.

8.

Increased expression of cannabinoid CB2 and serotonin 5-HT1A heteroreceptor complexes in a model of newborn hypoxic-ischemic brain damage.

Franco R, Villa M, Morales P, Reyes-Resina I, Gutiérrez-Rodríguez A, Jiménez J, Jagerovic N, Martínez-Orgado J, Navarro G.

Neuropharmacology. 2019 Jul 1;152:58-66. doi: 10.1016/j.neuropharm.2019.02.004. Epub 2019 Feb 7.

PMID:
30738036
9.

Cannabinoid Ligands Targeting TRP Channels.

Muller C, Morales P, Reggio PH.

Front Mol Neurosci. 2019 Jan 15;11:487. doi: 10.3389/fnmol.2018.00487. eCollection 2018. Review.

10.

Design and structural characterisation of monomeric water-soluble α-helix and β-hairpin peptides: State-of-the-art.

Morales P, Jiménez MA.

Arch Biochem Biophys. 2019 Jan;661:149-167. doi: 10.1016/j.abb.2018.11.014. Epub 2018 Nov 20. Review.

PMID:
30468710
11.

( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.

Liu Y, Ji L, Eno M, Kudalkar S, Li AL, Schimpgen M, Benchama O, Morales P, Xu S, Hurst D, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis DP, Zhou H, Honrao C, Mackie K, Reggio P, Hohmann AG, Marnett LJ, Makriyannis A, Nikas SP.

J Med Chem. 2018 Oct 11;61(19):8639-8657. doi: 10.1021/acs.jmedchem.8b00611. Epub 2018 Sep 21.

PMID:
30196704
12.

Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes.

Navarro G, Reyes-Resina I, Rivas-Santisteban R, Sánchez de Medina V, Morales P, Casano S, Ferreiro-Vera C, Lillo A, Aguinaga D, Jagerovic N, Nadal X, Franco R.

Biochem Pharmacol. 2018 Nov;157:148-158. doi: 10.1016/j.bcp.2018.08.046. Epub 2018 Sep 6.

PMID:
30194918
13.

Emerging strategies targeting CB2 cannabinoid receptor: Biased agonism and allosterism.

Morales P, Goya P, Jagerovic N.

Biochem Pharmacol. 2018 Nov;157:8-17. doi: 10.1016/j.bcp.2018.07.031. Epub 2018 Jul 26. Review.

PMID:
30055149
14.

Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type 2 Ligands.

Ragusa G, Bencivenni S, Morales P, Callaway T, Hurst DP, Asproni B, Merighi S, Loriga G, Pinna GA, Reggio PH, Gessi S, Murineddu G.

ChemMedChem. 2018 Jun 6;13(11):1102-1114. doi: 10.1002/cmdc.201800152. Epub 2018 Apr 16.

PMID:
29575721
15.

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12.

Morales P, Isawi I, Reggio PH.

Drug Metab Rev. 2018 Feb;50(1):74-93. doi: 10.1080/03602532.2018.1428616. Epub 2018 Feb 1. Review.

16.

An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors.

Morales P, Reggio PH.

Cannabis Cannabinoid Res. 2017 Oct 1;2(1):265-273. doi: 10.1089/can.2017.0036. eCollection 2017. Review.

17.

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes.

Sierra MI, Rubio L, Bayón GF, Cobo I, Menendez P, Morales P, Mangas C, Urdinguio RG, Lopez V, Valdes A, Vales G, Marcos R, Torrecillas R, Fernández AF, Fraga MF.

Nanotoxicology. 2017 Sep;11(7):857-870. doi: 10.1080/17435390.2017.1371350. Epub 2017 Sep 13.

PMID:
28901819
18.

Methods for the Development of In Silico GPCR Models.

Morales P, Hurst DP, Reggio PH.

Methods Enzymol. 2017;593:405-448. doi: 10.1016/bs.mie.2017.05.005. Epub 2017 Jul 14.

19.

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol.

Morales P, Reggio PH, Jagerovic N.

Front Pharmacol. 2017 Jun 28;8:422. doi: 10.3389/fphar.2017.00422. eCollection 2017. Review.

20.

Molecular Targets of the Phytocannabinoids: A Complex Picture.

Morales P, Hurst DP, Reggio PH.

Prog Chem Org Nat Prod. 2017;103:103-131. doi: 10.1007/978-3-319-45541-9_4. Review.

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