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Items: 1 to 20 of 80

1.

Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage.

Stefanoni D, Shin HKH, Baek JH, Champagne DP, Nemkov T, Thomas T, Francis RO, Zimring JC, Yoshida T, Reisz JA, Spitalnik SL, Buehler PW, D'Alessandro A.

Haematologica. 2019 Nov 7. pii: haematol.2019.229930. doi: 10.3324/haematol.2019.229930. [Epub ahead of print]

2.

Novel manufacturing method for producing apohemoglobin and its biophysical properties.

Pires IS, Belcher DA, Hickey R, Miller C, Badu-Tawiah AK, Baek JH, Buehler PW, Palmer AF.

Biotechnol Bioeng. 2020 Jan;117(1):125-145. doi: 10.1002/bit.27193. Epub 2019 Nov 15.

PMID:
31612988
3.

Can molecular markers of oxygen homeostasis and the measurement of tissue oxygen be leveraged to optimize red blood cell transfusions?

Baek JH, Buehler PW.

Curr Opin Hematol. 2019 Nov;26(6):453-460. doi: 10.1097/MOH.0000000000000533.

PMID:
31483333
4.

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.

Hugelshofer M, Buzzi RM, Schaer CA, Richter H, Akeret K, Anagnostakou V, Mahmoudi L, Vaccani R, Vallelian F, Deuel JW, Kronen PW, Kulcsar Z, Regli L, Baek JH, Pires IS, Palmer AF, Dennler M, Humar R, Buehler PW, Kircher PR, Keller E, Schaer DJ.

J Clin Invest. 2019 Dec 2;129(12):5219-5235. doi: 10.1172/JCI130630.

5.

An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease.

Redinus K, Baek JH, Yalamanoglu A, Shin HKH, Moldova R, Harral JW, Swindle D, Pak D, Ferguson SK, Nuss R, Hassell K, Nozik-Grayck E, Palmer AF, Fini MA, Karoor V, Stenmark KR, Buehler PW, Irwin DC.

JCI Insight. 2019 Aug 8;4(15). pii: 127860. doi: 10.1172/jci.insight.127860. eCollection 2019 Aug 8.

6.

Redox states of hemoglobin determine left ventricle pressure recovery and activity of mitochondrial complex IV in hypoxic rat hearts.

Edmondson M, Jana S, Meng F, Strader MB, Baek JH, Gao Y, Buehler PW, Alayash AI.

Free Radic Biol Med. 2019 Sep;141:348-361. doi: 10.1016/j.freeradbiomed.2019.07.008. Epub 2019 Jul 11.

PMID:
31302228
7.

Electron paramagnetic resonance oximetry as a novel approach to monitor the effectiveness and quality of red blood cell transfusions.

Hou H, Baek JH, Zhang H, Wood F, Gao Y, Flood AB, Swartz HM, Buehler PW.

Blood Transfus. 2019 Jul;17(4):296-306. doi: 10.2450/2019.0037-19. Epub 2019 May 16.

8.

Contradictory to its effects on thrombin, C1-inhibitor reduces plasmin generation in the presence of thrombomodulin.

Tarandovskiy ID, Rajabi AA, Karnaukhova E, Buehler PW.

J Thromb Thrombolysis. 2019 Jul;48(1):81-87. doi: 10.1007/s11239-019-01869-y.

PMID:
31030323
9.

C1-esterase inhibitor enhances thrombin generation and spatial fibrin clot propagation in the presence of thrombomodulin.

Tarandovskiy ID, Buehler PW, Ataullakhanov FI, Karnaukhova E.

Thromb Res. 2019 Apr;176:54-60. doi: 10.1016/j.thromres.2019.02.013. Epub 2019 Feb 12.

PMID:
30784776
10.

When might transferrin, hemopexin or haptoglobin administration be of benefit following the transfusion of red blood cells?

Buehler PW, Karnaukhova E.

Curr Opin Hematol. 2018 Nov;25(6):452-458. doi: 10.1097/MOH.0000000000000458. Review.

PMID:
30281034
11.

Attenuation of human hypoxic pulmonary vasoconstriction by acetazolamide and methazolamide.

Boulet LM, Teppema LJ, Hackett HK, Dominelli PB, Cheyne WS, Dominelli GS, Irwin DC, Buehler PW, Baek JH, Swenson ER, Foster GE.

J Appl Physiol (1985). 2018 Sep 20. doi: 10.1152/japplphysiol.00509.2018. [Epub ahead of print]

PMID:
30236048
12.

Renal Toxicodynamic Effects of Extracellular Hemoglobin After Acute Exposure.

Baek JH, Yalamanoglu A, Brown RP, Saylor DM, Malinauskas RA, Buehler PW.

Toxicol Sci. 2018 Nov 1;166(1):180-191. doi: 10.1093/toxsci/kfy193.

PMID:
30085279
13.

Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease.

Yalamanoglu A, Deuel JW, Hunt RC, Baek JH, Hassell K, Redinius K, Irwin DC, Schaer DJ, Buehler PW.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L765-L774. doi: 10.1152/ajplung.00269.2018. Epub 2018 Jul 26.

14.

Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anaemia.

Ferguson SK, Redinius K, Yalamanoglu A, Harral JW, Hyen Baek J, Pak D, Loomis Z, Hassell D, Eigenberger P, Nozik-Grayck E, Nuss R, Hassell K, Stenmark KR, Buehler PW, Irwin DC.

J Physiol. 2019 Feb;597(4):1073-1085. doi: 10.1113/JP275810. Epub 2018 Aug 25.

PMID:
29931797
15.

Predicting Plasma Free Hemoglobin Levels in Patients Due to Medical Device-Related Hemolysis.

Saylor DM, Buehler PW, Brown RP, Malinauskas RA.

ASAIO J. 2019 Mar/Apr;65(3):207-218. doi: 10.1097/MAT.0000000000000801.

PMID:
29750685
16.

Revisiting the putative role of heme as a trigger of inflammation.

Vallelian F, Schaer CA, Deuel JW, Ingoglia G, Humar R, Buehler PW, Schaer DJ.

Pharmacol Res Perspect. 2018 Mar 30;6(2):e00392. doi: 10.1002/prp2.392. eCollection 2018 Apr.

17.

Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics.

Schaer CA, Owczarek C, Deuel JW, Schauer S, Baek JH, Yalamanoglu A, Hardy MP, Scotney PD, Schmidt PM, Pelzing M, Soupourmas P, Buehler PW, Schaer DJ.

BMC Biotechnol. 2018 Mar 15;18(1):15. doi: 10.1186/s12896-018-0424-3.

18.

Impact of cell-free hemoglobin on contracting skeletal muscle microvascular oxygen pressure dynamics.

Ferguson SK, Harral JW, Pak DI, Redinius KM, Stenmark KR, Schaer DJ, Buehler PW, Irwin DC.

Nitric Oxide. 2018 Jun 1;76:29-36. doi: 10.1016/j.niox.2018.03.005. Epub 2018 Mar 8.

PMID:
29526566
19.

Evaluation of renal oxygen homeostasis in a preclinical animal model to elucidate difference in blood quality after transfusion.

Baek JH, Yalamanoglu A, Moon SE, Gao Y, Buehler PW.

Transfusion. 2018 Jun;58(6):1474-1485. doi: 10.1111/trf.14560. Epub 2018 Mar 1.

PMID:
29498054
20.

The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study.

Belcher DA, Ju JA, Baek JH, Yalamanoglu A, Buehler PW, Gilkes DM, Palmer AF.

PLoS One. 2018 Feb 7;13(2):e0191275. doi: 10.1371/journal.pone.0191275. eCollection 2018.

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