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Items: 1 to 20 of 62

1.

Functionally Versatile and Highly Stable Chelator for 111In and 177Lu: Proof-of-Principle Prostate-Specific Membrane Antigen Targeting.

Li L, Jaraquemada-Peláez MG, Kuo HT, Merkens H, Choudhary N, Gitschtaler K, Jermilova U, Colpo N, Uribe-Munoz C, Radchenko V, Schaffer P, Lin KS, Bénard F, Orvig C.

Bioconjug Chem. 2019 May 15;30(5):1539-1553. doi: 10.1021/acs.bioconjchem.9b00225. Epub 2019 May 5.

PMID:
31009566
2.

Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.

Lim JKM, Delaidelli A, Minaker SW, Zhang HF, Colovic M, Yang H, Negri GL, von Karstedt S, Lockwood WW, Schaffer P, Leprivier G, Sorensen PH.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9433-9442. doi: 10.1073/pnas.1821323116. Epub 2019 Apr 18.

3.

Non-invasive Use of Positron Emission Tomography to Monitor Diethyl maleate and Radiation-Induced Changes in System xC- Activity in Breast Cancer.

Čolović M, Yang H, Merkens H, Colpo N, Bénard F, Schaffer P.

Mol Imaging Biol. 2019 Mar 5. doi: 10.1007/s11307-019-01331-8. [Epub ahead of print]

PMID:
30838549
4.

18F-Branched-Chain Amino Acids: Structure-Activity Relationships and PET Imaging Potential.

Nodwell MB, Yang H, Merkens H, Malik N, Čolović M, Björn Wagner, Martin RE, Bénard F, Schaffer P, Britton R.

J Nucl Med. 2019 Jul;60(7):1003-1009. doi: 10.2967/jnumed.118.220483. Epub 2019 Jan 25.

PMID:
30683769
5.

The Evolving Clinical Role of Actinium-225 and Bismuth-213 for Targeted Alpha Therapy (TAT) - Production, Radiopharmaceutical Development and Clinical Applications.

Radchenko V, Schaffer P, Knapp FFR.

Curr Radiopharm. 2018;11(3):154-155. doi: 10.2174/187447101103180911115600.

PMID:
30378473
6.

Synthesis and evaluation of an 18F-labeled boramino acid analog of aminosuberic acid for PET imaging of the antiporter system xC<sup/>.

Čolović M, Rousseau E, Zhang Z, Lau J, Zhang C, Kuo HT, Yang H, Schaffer P, François Bénard, Lin KS.

Bioorg Med Chem Lett. 2018 Dec 1;28(22):3579-3584. doi: 10.1016/j.bmcl.2018.06.014. Epub 2018 Jun 8.

PMID:
30316632
7.

Design, synthesis and anti-mycobacterial activity evaluation of benzofuran-isatin hybrids.

Gao F, Yang H, Lu T, Chen Z, Ma L, Xu Z, Schaffer P, Lu G.

Eur J Med Chem. 2018 Nov 5;159:277-281. doi: 10.1016/j.ejmech.2018.09.049. Epub 2018 Sep 18.

PMID:
30296686
8.

Direct observation of Mg2+ complexes in ionic liquid solutions by 31Mg β-NMR spectroscopy.

Szunyogh D, McFadden RML, Karner VL, Chatzichristos A, Day Goodacre T, Dehn MH, Formenti L, Fujimoto D, Gottberg A, Kallenberg E, Kálomista I, Kiefl RF, Larsen FH, Lassen J, Levy CDP, Li R, MacFarlane WA, McKenzie I, Morris GD, Pallada S, Pearson MR, Sauer SPA, Schaffer P, Thulstrup PW, Hemmingsen L, Stachura M.

Dalton Trans. 2018 Oct 23;47(41):14431-14435. doi: 10.1039/c8dt02350f.

PMID:
30280170
9.

Site-Selective, Late-Stage C-H 18 F-Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging.

Yuan Z, Nodwell MB, Yang H, Malik N, Merkens H, Bénard F, Martin RE, Schaffer P, Britton R.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12733-12736. doi: 10.1002/anie.201806966. Epub 2018 Sep 5.

PMID:
30086209
10.

Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives.

Meanwell M, Adluri BS, Yuan Z, Newton J, Prevost P, Nodwell MB, Friesen CM, Schaffer P, Martin RE, Britton R.

Chem Sci. 2018 Jun 7;9(25):5608-5613. doi: 10.1039/c8sc01221k. eCollection 2018 Jul 7.

11.

Development of 225Ac Radiopharmaceuticals: TRIUMF Perspectives and Experiences.

Robertson AKH, Ramogida CF, Schaffer P, Radchenko V.

Curr Radiopharm. 2018;11(3):156-172. doi: 10.2174/1874471011666180416161908. Review.

12.

Evaluation of <sup>209</sup>At as a theranostic isotope for <sup>211</sup>At-radiopharmaceutical development using high-energy SPECT.

Crawford JR, Robertson AKH, Yang H, Rodriguez-Rodriguez C, Esquinas PL, Kunz P, Blinder S, Sossi V, Schaffer P, Ruth TJ.

Phys Med Biol. 2018 Jan 25. doi: 10.1088/1361-6560/aaaa95. [Epub ahead of print]

PMID:
29369043
13.

89Zr for antibody labeling and in vivo studies - A comparison between liquid and solid target production.

Dias GM, Ramogida CF, Rousseau J, Zacchia NA, Hoehr C, Schaffer P, Lin KS, Bénard F.

Nucl Med Biol. 2018 Mar;58:1-7. doi: 10.1016/j.nucmedbio.2017.11.005. Epub 2017 Nov 16.

PMID:
29291493
14.

An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy.

Thiele NA, Brown V, Kelly JM, Amor-Coarasa A, Jermilova U, MacMillan SN, Nikolopoulou A, Ponnala S, Ramogida CF, Robertson AKH, Rodríguez-Rodríguez C, Schaffer P, Williams C Jr, Babich JW, Radchenko V, Wilson JJ.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717. doi: 10.1002/anie.201709532. Epub 2017 Oct 16.

PMID:
28963750
15.

Addressing Chirality in the Structure and Synthesis of [18 F]5-Fluoroaminosuberic Acid ([18 F]FASu).

Yang H, Tam B, Čolović M, Southcott L, Merkens H, Bénard F, Schaffer P.

Chemistry. 2017 Aug 16;23(46):11100-11107. doi: 10.1002/chem.201702007. Epub 2017 Jul 26.

PMID:
28744973
16.

A new tetrapodal 3-hydroxy-4-pyridinone ligand for complexation of 89zirconium for positron emission tomography (PET) imaging.

Buchwalder C, Rodríguez-Rodríguez C, Schaffer P, Karagiozov SK, Saatchi K, Häfeli UO.

Dalton Trans. 2017 Jul 25;46(29):9654-9663. doi: 10.1039/c7dt02196h.

PMID:
28713886
17.

p-NO2-Bn-H4neunpa and H4neunpa-Trastuzumab: Bifunctional Chelator for Radiometalpharmaceuticals and 111In Immuno-Single Photon Emission Computed Tomography Imaging.

Spreckelmeyer S, Ramogida CF, Rousseau J, Arane K, Bratanovic I, Colpo N, Jermilova U, Dias GM, Dude I, Jaraquemada-Peláez MG, Bénard F, Schaffer P, Orvig C.

Bioconjug Chem. 2017 Aug 16;28(8):2145-2159. doi: 10.1021/acs.bioconjchem.7b00311. Epub 2017 Aug 1.

PMID:
28683198
18.

PBB3 imaging in Parkinsonian disorders: Evidence for binding to tau and other proteins.

Perez-Soriano A, Arena JE, Dinelle K, Miao Q, McKenzie J, Neilson N, Puschmann A, Schaffer P, Shinotoh H, Smith-Forrester J, Shahinfard E, Vafai N, Wile D, Wszolek Z, Higuchi M, Sossi V, Stoessl AJ.

Mov Disord. 2017 Jul;32(7):1016-1024. doi: 10.1002/mds.27029. Epub 2017 Jun 1.

PMID:
28568506
19.

Manganese concentration mapping in the rat brain with MRI, PET, and autoradiography.

Topping GJ, Yung A, Schaffer P, Hoehr C, Kornelsen R, Kozlowski P, Sossi V.

Med Phys. 2017 Aug;44(8):4056-4067. doi: 10.1002/mp.12300. Epub 2017 Jul 5.

PMID:
28444763
20.

Multi-isotope SPECT imaging of the 225Ac decay chain: feasibility studies.

Robertson AKH, Ramogida CF, Rodríguez-Rodríguez C, Blinder S, Kunz P, Sossi V, Schaffer P.

Phys Med Biol. 2017 Jun 7;62(11):4406-4420. doi: 10.1088/1361-6560/aa6a99. Epub 2017 Mar 31.

PMID:
28362640

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