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Items: 1 to 20 of 43


Retinoic acid signalling adjusts tight junction permeability in response to air-liquid interface conditions.

Lochbaum R, Schilpp C, Nonnenmacher L, Frick M, Dietl P, Wittekindt OH.

Cell Signal. 2020 Jan;65:109421. doi: 10.1016/j.cellsig.2019.109421. Epub 2019 Sep 16.


IL-13 Impairs Tight Junctions in Airway Epithelia.

Schmidt H, Braubach P, Schilpp C, Lochbaum R, Neuland K, Thompson K, Jonigk D, Frick M, Dietl P, Wittekindt OH.

Int J Mol Sci. 2019 Jun 30;20(13). pii: E3222. doi: 10.3390/ijms20133222.


Aquaporins in the lung.

Wittekindt OH, Dietl P.

Pflugers Arch. 2019 Apr;471(4):519-532. doi: 10.1007/s00424-018-2232-y. Epub 2018 Nov 5. Review.


Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia.

Winkelmann VE, Thompson KE, Neuland K, Jaramillo AM, Fois G, Schmidt H, Wittekindt OH, Han W, Tuvim MJ, Dickey BF, Dietl P, Frick M.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L58-L70. doi: 10.1152/ajplung.00157.2018. Epub 2018 Oct 25.


P2X4 receptor re-sensitization depends on a protonation/deprotonation cycle mediated by receptor internalization and recycling.

Fois G, Föhr KJ, Kling C, Fauler M, Wittekindt OH, Dietl P, Frick M.

J Physiol. 2018 Oct;596(20):4893-4907. doi: 10.1113/JP275448. Epub 2018 Sep 17.


Pulmonary surfactant protein SP-B promotes exocytosis of lamellar bodies in alveolar type II cells.

Martínez-Calle M, Olmeda B, Dietl P, Frick M, Pérez-Gil J.

FASEB J. 2018 Aug;32(8):4600-4611. doi: 10.1096/fj.201701462RR. Epub 2018 Mar 15.


Silver Nanoparticles Impair Retinoic Acid-Inducible Gene I-Mediated Mitochondrial Antiviral Immunity by Blocking the Autophagic Flux in Lung Epithelial Cells.

Villeret B, Dieu A, Straube M, Solhonne B, Miklavc P, Hamadi S, Le Borgne R, Mailleux A, Norel X, Aerts J, Diallo D, Rouzet F, Dietl P, Sallenave JM, Garcia-Verdugo I.

ACS Nano. 2018 Feb 27;12(2):1188-1202. doi: 10.1021/acsnano.7b06934. Epub 2018 Jan 30.


Water Permeability Adjusts Resorption in Lung Epithelia to Increased Apical Surface Liquid Volumes.

Schmidt H, Michel C, Braubach P, Fauler M, Neubauer D, Thompson KE, Frick M, Mizaikoff B, Dietl P, Wittekindt OH.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):372-382. doi: 10.1165/rcmb.2016-0161OC.


A small key unlocks a heavy door: The essential function of the small hydrophobic proteins SP-B and SP-C to trigger adsorption of pulmonary surfactant lamellar bodies.

Hobi N, Giolai M, Olmeda B, Miklavc P, Felder E, Walther P, Dietl P, Frick M, Pérez-Gil J, Haller T.

Biochim Biophys Acta. 2016 Aug;1863(8):2124-34. doi: 10.1016/j.bbamcr.2016.04.028. Epub 2016 May 4.


A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca²⁺ release from acidic Ca²⁺ stores.

Fois G, Hobi N, Felder E, Ziegler A, Miklavc P, Walther P, Radermacher P, Haller T, Dietl P.

Cell Calcium. 2015 Dec;58(6):628-37. doi: 10.1016/j.ceca.2015.10.002. Epub 2015 Oct 27.


Glucocorticoids Regulate Tight Junction Permeability of Lung Epithelia by Modulating Claudin 8.

Kielgast F, Schmidt H, Braubach P, Winkelmann VE, Thompson KE, Frick M, Dietl P, Wittekindt OH.

Am J Respir Cell Mol Biol. 2016 May;54(5):707-17. doi: 10.1165/rcmb.2015-0071OC.


Physiological and immune-biological characterization of a long-term murine model of blunt chest trauma.

Hafner S, Wagner K, Wepler M, Matallo J, Gröger M, McCook O, Scheuerle A, Huber-Lang M, Frick M, Weber S, Stahl B, Jung B, Calzia E, Georgieff M, Möller P, Dietl P, Radermacher P, Wagner F.

Shock. 2015 Feb;43(2):140-7. doi: 10.1097/SHK.0000000000000277. Erratum in: Shock. 2015 Apr;43(4):425.


Hyperglycemia, oxidative stress, and the diaphragm: a link between chronic co-morbidity and acute stress?

Hafner S, Radermacher P, Frick M, Dietl P, Calzia E.

Crit Care. 2014 Jun 10;18(3):149. doi: 10.1186/cc13913.


Amiloride-sensitive fluid resorption in NCI-H441 lung epithelia depends on an apical Cl(-) conductance.

Korbmacher JP, Michel C, Neubauer D, Thompson K, Mizaikoff B, Frick M, Dietl P, Wittekindt OH.

Physiol Rep. 2014 Jan 16;2(1):e00201. doi: 10.1002/phy2.201. eCollection 2014 Jan 1.


Deuterium oxide dilution: a novel method to study apical water layers and transepithelial water transport.

Neubauer D, Korbmacher J, Frick M, Kiss J, Timmler M, Dietl P, Wittekindt OH, Mizaikoff B.

Anal Chem. 2013 May 7;85(9):4247-50. doi: 10.1021/ac4002723. Epub 2013 Apr 11.


Fusion-activated cation entry (FACE) via P2X₄ couples surfactant secretion and alveolar fluid transport.

Thompson KE, Korbmacher JP, Hecht E, Hobi N, Wittekindt OH, Dietl P, Kranz C, Frick M.

FASEB J. 2013 Apr;27(4):1772-83. doi: 10.1096/fj.12-220533. Epub 2013 Jan 10.


Effects of keratin phosphorylation on the mechanical properties of keratin filaments in living cells.

Fois G, Weimer M, Busch T, Felder ET, Oswald F, von Wichert G, Seufferlein T, Dietl P, Felder E.

FASEB J. 2013 Apr;27(4):1322-9. doi: 10.1096/fj.12-215632. Epub 2012 Dec 14.


Combined atomic force microscopy-fluorescence microscopy: analyzing exocytosis in alveolar type II cells.

Hecht E, Thompson K, Frick M, Wittekindt OH, Dietl P, Mizaikoff B, Kranz C.

Anal Chem. 2012 Jul 3;84(13):5716-22. doi: 10.1021/ac300775j. Epub 2012 Jun 22.


Spatio-temporal aspects, pathways and actions of Ca(2+) in surfactant secreting pulmonary alveolar type II pneumocytes.

Dietl P, Haller T, Frick M.

Cell Calcium. 2012 Sep-Oct;52(3-4):296-302. doi: 10.1016/j.ceca.2012.04.010. Epub 2012 May 14. Review.


Actin coating and compression of fused secretory vesicles are essential for surfactant secretion--a role for Rho, formins and myosin II.

Miklavc P, Hecht E, Hobi N, Wittekindt OH, Dietl P, Kranz C, Frick M.

J Cell Sci. 2012 Jun 1;125(Pt 11):2765-74. doi: 10.1242/jcs.105262. Epub 2012 Mar 16.

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