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Items: 1 to 20 of 22

1.

The Activation of the Chymotrypsin-Like Activity of the Proteasome is Regulated by Soluble Adenyl Cyclase / cAMP / Protein Kinase a Pathway and Required for Human Sperm Capacitation.

Zapata-Carmona H, Barón L, Zuñiga LM, Díaz ES, Kong M, Drobnis EZ, Sutovsky P, Morales P.

Mol Hum Reprod. 2019 Jul 22. pii: gaz037. doi: 10.1093/molehr/gaz037. [Epub ahead of print]

PMID:
31329238
2.

Re-Epithelialization Appraisal of Skin Wound in a Porcine Model Using a Salmon-Gelatin Based Biomaterial as Wound Dressing.

Acevedo CA, Sánchez E, Orellana N, Morales P, Olguín Y, Brown DI, Enrione J.

Pharmaceutics. 2019 Apr 26;11(5). pii: E196. doi: 10.3390/pharmaceutics11050196.

3.

Fibronectin modulates the endocannabinoid system through the cAMP/PKA pathway during human sperm capacitation.

Martínez-León E, Osycka-Salut C, Signorelli J, Kong M, Morales P, Pérez-Martínez S, Díaz ES.

Mol Reprod Dev. 2019 Feb;86(2):224-238. doi: 10.1002/mrd.23097. Epub 2019 Jan 10.

PMID:
30582781
4.

Design of a hybrid biomaterial for tissue engineering: Biopolymer-scaffold integrated with an autologous hydrogel carrying mesenchymal stem-cells.

Weinstein-Oppenheimer CR, Brown DI, Coloma R, Morales P, Reyna-Jeldes M, Díaz MJ, Sánchez E, Acevedo CA.

Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:821-830. doi: 10.1016/j.msec.2017.05.116. Epub 2017 May 17.

PMID:
28629085
5.

Regulation of Sperm Capacitation by the 26S Proteasome: An Emerging New Paradigm in Spermatology.

Kerns K, Morales P, Sutovsky P.

Biol Reprod. 2016 May;94(5):117. doi: 10.1095/biolreprod.115.136622. Epub 2016 Apr 6. Review.

PMID:
27053366
6.

Protein phosphatases decrease their activity during capacitation: a new requirement for this event.

Signorelli JR, Díaz ES, Fara K, Barón L, Morales P.

PLoS One. 2013 Dec 2;8(12):e81286. doi: 10.1371/journal.pone.0081286. eCollection 2013.

7.

Aromatic glycosyl disulfide derivatives: evaluation of their inhibitory activities against Trypanosoma cruzi.

Gutiérrez B, Muñoz C, Osorio L, Fehér K, Illyés TZ, Papp Z, Kumar AA, Kövér KE, Sagua H, Araya JE, Morales P, Szilágyi L, González J.

Bioorg Med Chem Lett. 2013 Jun 15;23(12):3576-9. doi: 10.1016/j.bmcl.2013.04.030. Epub 2013 Apr 22.

PMID:
23659860
8.

A protein phosphatase 1 gamma (PP1γ) of the human protozoan parasite Trichomonas vaginalis is involved in proliferation and cell attachment to the host cell.

Muñoz C, Pérez M, Orrego PR, Osorio L, Gutiérrez B, Sagua H, Castillo JL, Martínez-Oyanedel J, Arroyo R, Meza-Cervantez P, da Silveira JF, Midlej V, Benchimol M, Cordero E, Morales P, Araya JE, González J.

Int J Parasitol. 2012 Jul;42(8):715-27. doi: 10.1016/j.ijpara.2012.03.012. Epub 2012 Jun 16.

PMID:
22713760
9.

Kinases, phosphatases and proteases during sperm capacitation.

Signorelli J, Diaz ES, Morales P.

Cell Tissue Res. 2012 Sep;349(3):765-82. doi: 10.1007/s00441-012-1370-3. Epub 2012 Mar 20. Review.

PMID:
22427115
10.

N,N'-Dithiobisphthalimide, a disulfide aromatic compound, is a potent spermicide agent in humans.

Florez M, Díaz ES, Brito I, González J, Morales P.

Syst Biol Reprod Med. 2011 Dec;57(6):309-17. doi: 10.3109/19396368.2011.613977. Epub 2011 Sep 26.

PMID:
21942567
11.

The laminin-induced acrosome reaction in human sperm is mediated by Src kinases and the proteasome.

Tapia S, Rojas M, Morales P, Ramirez MA, Diaz ES.

Biol Reprod. 2011 Aug;85(2):357-66. doi: 10.1095/biolreprod.111.092254. Epub 2011 May 4.

PMID:
21543765
12.

The effect of an autologous cellular gel-matrix integrated implant system on wound healing.

Weinstein-Oppenheimer CR, Aceituno AR, Brown DI, Acevedo C, Ceriani R, Fuentes MA, Albornoz F, Henríquez-Roldán CF, Morales P, Maclean C, Tapia SM, Young ME.

J Transl Med. 2010 Jun 17;8:59. doi: 10.1186/1479-5876-8-59.

13.

Participation of the human sperm proteasome in the capacitation process and its regulation by protein kinase A and tyrosine kinase.

Kong M, Diaz ES, Morales P.

Biol Reprod. 2009 May;80(5):1026-35. doi: 10.1095/biolreprod.108.073924. Epub 2009 Jan 14.

PMID:
19144957
14.

The role of sperm proteasomes during sperm aster formation and early zygote development: implications for fertilization failure in humans.

Rawe VY, Díaz ES, Abdelmassih R, Wójcik C, Morales P, Sutovsky P, Chemes HE.

Hum Reprod. 2008 Mar;23(3):573-80. Epub 2007 Dec 17.

PMID:
18089554
15.
16.
17.

Role of the sperm proteasome during fertilization and gamete interaction in the mouse.

Pasten C, Morales P, Kong M.

Mol Reprod Dev. 2005 Jun;71(2):209-19.

PMID:
15791592
18.

Proteasomal activity in mammalian spermatozoa.

Pizarro E, Pastén C, Kong M, Morales P.

Mol Reprod Dev. 2004 Sep;69(1):87-93.

PMID:
15278908
19.

Extracellular localization of proteasomes in human sperm.

Morales P, Pizarro E, Kong M, Jara M.

Mol Reprod Dev. 2004 May;68(1):115-24.

PMID:
15039955
20.

Effect of azorellanone, a diterpene from Azorella yareta Hauman, on human sperm physiology.

Morales P, Kong M, Pizarro E, Pasten C, Morales G, Borquez J, Loyola LA.

J Androl. 2003 May-Jun;24(3):364-70.

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