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Items: 1 to 20 of 218

1.

Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors.

Lanman BA, Allen JR, Allen JG, Amegadzie AK, Ashton KS, Booker SK, Chen JJ, Chen N, Frohn MJ, Goodman G, Kopecky DJ, Liu L, Lopez P, Low JD, Ma V, Minatti AE, Nguyen TT, Nishimura N, Pickrell AJ, Reed AB, Shin Y, Siegmund AC, Tamayo NA, Tegley CM, Walton MC, Wang HL, Wurz RP, Xue M, Yang KC, Achanta P, Bartberger MD, Canon J, Hollis LS, McCarter JD, Mohr C, Rex K, Saiki AY, San Miguel T, Volak LP, Wang KH, Whittington DA, Zech SG, Lipford JR, Cee VJ.

J Med Chem. 2020 Jan 9;63(1):52-65. doi: 10.1021/acs.jmedchem.9b01180. Epub 2019 Dec 24.

PMID:
31820981
2.

In Vivo Validation of a Small Molecule Inhibitor of Tau Self-Association in htau Mice.

Davidowitz EJ, Krishnamurthy PK, Lopez P, Jimenez H, Adrien L, Davies P, Moe JG.

J Alzheimers Dis. 2020;73(1):147-161. doi: 10.3233/JAD-190465.

3.

Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease.

Vos MB, Dimick-Santos L, Mehta R, Omokaro SO, Taminiau J, Schabel E, Kleiner DE, Szitanyi P, Socha P, Schwimmer JB, Noviello S, Silberg DG, Torstenson R, Miller V, Lavine JE; Liver Forum Pediatric Working Group.

Gastroenterology. 2019 Dec;157(6):1448-1456.e1. doi: 10.1053/j.gastro.2019.08.048. Epub 2019 Sep 12. No abstract available.

PMID:
31520612
4.

Silencing of the transcription factors Oct4, Sox2, Klf4, c-Myc or Nanog has different effect on teratoma growth.

Villodre ES, Felipe KB, Oyama MZ, Oliveira FH, Lopez PLDC, Solari C, Sevlever G, Guberman A, Lenz G.

Biochem Biophys Res Commun. 2019 Sep 17;517(2):324-329. doi: 10.1016/j.bbrc.2019.07.064. Epub 2019 Jul 25.

PMID:
31353083
5.

IgM anti-phosphorylcholine antibodies associate with senescent and IL-17+ T cells in SLE patients with a pro-inflammatory lipid profile.

López P, Rodríguez-Carrio J, Martínez-Zapico A, Pérez-Álvarez ÁI, Benavente L, Caminal-Montero L, Suárez A.

Rheumatology (Oxford). 2019 Jul 13. pii: kez264. doi: 10.1093/rheumatology/kez264. [Epub ahead of print]

PMID:
31302689
6.

Straining Flow Spinning of Artificial Silk Fibers: A Review.

Pérez-Rigueiro J, Madurga R, Gañán-Calvo AM, Plaza GR, Elices M, López PA, Daza R, González-Nieto D, Guinea GV.

Biomimetics (Basel). 2018 Oct 5;3(4). pii: E29. doi: 10.3390/biomimetics3040029. Review.

7.

Genistein increases the thermogenic program of subcutaneous WAT and increases energy expenditure in mice.

Palacios-González B, Vargas-Castillo A, Velázquez-Villegas LA, Vasquez-Reyes S, López P, Noriega LG, Aleman G, Tovar-Palacio C, Torre-Villalvazo I, Yang LJ, Zarain-Herzberg A, Torres N, Tovar AR.

J Nutr Biochem. 2019 Jun;68:59-68. doi: 10.1016/j.jnutbio.2019.03.012. Epub 2019 Mar 29.

PMID:
31030168
8.

Vitamin D Receptor Polymorphism and DHCR7 Contribute to the Abnormal Interplay Between Vitamin D and Lipid Profile in Rheumatoid Arthritis.

Rodríguez-Carrio J, Alperi-López M, Naves-Díaz M, Dusso A, López P, Ballina-García FJ, Cannata-Andía JB, Suárez A.

Sci Rep. 2019 Feb 22;9(1):2546. doi: 10.1038/s41598-019-38756-8.

9.

IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis.

Rodríguez-Carrio J, López P, Alperi-López M, Caminal-Montero L, Ballina-García FJ, Suárez A.

Front Immunol. 2019 Jan 7;9:3085. doi: 10.3389/fimmu.2018.03085. eCollection 2018.

10.

Earlier puberty in boys with type 1 diabetes mellitus compared to a simultaneously recruited group of control adolescents.

Gaete X, Vivanco M, Lopez P, Rocha A, Sepúlveda C, Codner E.

Pediatr Diabetes. 2019 Mar;20(2):197-201. doi: 10.1111/pedi.12811. Epub 2019 Jan 8.

PMID:
30575242
11.

Effects of ALAD genotype on the relationship between lead exposure and anthropometry in a Cohort of Mexican children.

Kerr BT, Ochs-Balcom HM, López P, García-Vargas GG, Rosado JL, Cebrián ME, Kordas K.

Environ Res. 2019 Mar;170:65-72. doi: 10.1016/j.envres.2018.12.003. Epub 2018 Dec 5.

PMID:
30557693
12.

Ovarian Function in Adolescents Conceived Using Assisted Reproductive Technologies.

Merino PM, Lopez P, Salinas A, Pastene C, Muñoz A, Cassorla F, Codner E.

J Pediatr Adolesc Gynecol. 2019 Apr;32(2):117-121. doi: 10.1016/j.jpag.2018.11.008. Epub 2018 Nov 28.

PMID:
30502496
13.

The Effect of Peer-Group Argumentative Dialogue on Delayed Gains in Scientific Content Knowledge.

Larrain A, Freire P, Grau V, López P, Salvat I, Silva M, Gastellu V.

New Dir Child Adolesc Dev. 2018 Dec;2018(162):67-87. doi: 10.1002/cad.20263. Epub 2018 Oct 29.

PMID:
30371974
14.

Profiling of B-Cell Factors and Their Decoy Receptors in Rheumatoid Arthritis: Association With Clinical Features and Treatment Outcomes.

Rodríguez-Carrio J, Alperi-López M, López P, Ballina-García FJ, Suárez A.

Front Immunol. 2018 Oct 11;9:2351. doi: 10.3389/fimmu.2018.02351. eCollection 2018.

15.

Food protein-induced enterocolitis syndrome: Increased prevalence of this great unknown-results of the PREVALE study.

Alonso SB, Ezquiaga JG, Berzal PT, Tardón SD, San José MM, López PA, Bermejo TB, Teruel SQ, Echeverría Zudaire LÁ.

J Allergy Clin Immunol. 2019 Jan;143(1):430-433. doi: 10.1016/j.jaci.2018.08.045. Epub 2018 Sep 20. No abstract available.

PMID:
30244024
16.

Could Fecal Phenylacetic and Phenylpropionic Acids Be Used as Indicators of Health Status?

Gutiérrez-Díaz I, Fernández-Navarro T, Salazar N, Bartolomé B, Moreno-Arribas MV, López P, Suárez A, de Los Reyes-Gavilán CG, Gueimonde M, González S.

J Agric Food Chem. 2018 Oct 10;66(40):10438-10446. doi: 10.1021/acs.jafc.8b04102. Epub 2018 Sep 28.

PMID:
30227707
17.

The role of gut microbiota in lupus: what we know in 2018?

Ruiz L, López P, Suárez A, Sánchez B, Margolles A.

Expert Rev Clin Immunol. 2018 Oct;14(10):787-792. doi: 10.1080/1744666X.2018.1519395. Epub 2018 Sep 8. Review.

PMID:
30173572
18.

Early conversion of pediatric kidney transplant patients to everolimus with reduced tacrolimus and steroid elimination: Results of a randomized trial.

Tönshoff B, Ettenger R, Dello Strologo L, Marks SD, Pape L, Tedesco-Silva H Jr, Bjerre A, Christian M, Meier M, Martzloff ED, Rauer B, Ng J, Lopez P.

Am J Transplant. 2019 Mar;19(3):811-822. doi: 10.1111/ajt.15081. Epub 2018 Oct 18.

PMID:
30125462
19.

Long-Term Genistein Consumption Modifies Gut Microbiota, Improving Glucose Metabolism, Metabolic Endotoxemia, and Cognitive Function in Mice Fed a High-Fat Diet.

López P, Sánchez M, Perez-Cruz C, Velázquez-Villegas LA, Syeda T, Aguilar-López M, Rocha-Viggiano AK, Del Carmen Silva-Lucero M, Torre-Villalvazo I, Noriega LG, Torres N, Tovar AR.

Mol Nutr Food Res. 2018 Aug;62(16):e1800313. doi: 10.1002/mnfr.201800313. Epub 2018 Jul 29.

PMID:
29979819
20.

Low Cost Photonic Sensor for in-Line Oil Quality Monitoring: Methodological Development Process towards Uncertainty Mitigation.

Lopez P, Mabe J, Miró G, Etxeberria L.

Sensors (Basel). 2018 Jun 22;18(7). pii: E2015. doi: 10.3390/s18072015.

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