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A Decade of Antifungal Leads from Natural Products: 2010-2019.

Aldholmi M, Marchand P, Ourliac-Garnier I, Le Pape P, Ganesan A.

Pharmaceuticals (Basel). 2019 Dec 12;12(4). pii: E182. doi: 10.3390/ph12040182. Review.


27th Annual GP2A Medicinal Chemistry Conference.

Mistry SN, Marchand P, Kellam B.

Pharmaceuticals (Basel). 2019 Dec 6;12(4). pii: E179. doi: 10.3390/ph12040179.


Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents.

Nascimento da Cruz AC, Brondani DJ, I Talo de Santana T, Oliveira da Silva L, da Oliveira Borba EF, de Faria AR, Ferreira Cavalcanti de Albuquerque J, Piessard S, Matos Ximenes R, Baratte B, Bach S, Ruchaud S, Bezerra Mendonça Junior FJ, Bazin MA, Montenegro Rabello M, Hernandes MZ, Marchand P, Gonçalves da Silva T.

Pharmaceuticals (Basel). 2019 Nov 17;12(4). pii: E169. doi: 10.3390/ph12040169.


Design, synthesis and pharmacological evaluation of CVIB, a codrug of carvacrol and ibuprofen as a novel anti-inflammatory agent.

de Oliveira Pedrosa Rolim M, de Almeida AR, da Rocha Pitta MG, de Melo Rêgo MJB, Quintans-Júnior LJ, de Souza Siqueira Quintans J, Heimfarth L, Scotti L, Scotti MT, da Cruz RMD, de Almeida RN, da Silva TG, de Oliveira JA, de Campos ML, Marchand P, Mendonça-Junior FJB.

Int Immunopharmacol. 2019 Nov;76:105856. doi: 10.1016/j.intimp.2019.105856. Epub 2019 Aug 31.


Thiazolidinedione and thiazole derivatives potentiate norfloxacin activity against NorA efflux pump over expression in Staphylococcus aureus 1199B strains.

Pereira PS, Lima MDCA, Neto PPM, Oliveira-Tintino CDM, Tintino SR, Menezes IRA, de Oliveira JF, Marchand P, Coutinho HDM, Rodrigues MDD, da Silva TG.

Bioorg Med Chem. 2019 Sep 1;27(17):3797-3804. doi: 10.1016/j.bmc.2019.07.006. Epub 2019 Jul 4.


5-Nitro-Thiophene-Thiosemicarbazone Derivatives Present Antitumor Activity Mediated by Apoptosis and DNA Intercalation.

Roque Marques KM, do Desterro MR, de Arruda SM, de Araújo Neto LN, do Carmo Alves de Lima M, de Almeida SMV, da Silva ECD, de Aquino TM, da Silva-Júnior EF, de Araújo-Júnior JX, de M Silva M, de A Dantas MD, Santos JCC, Figueiredo IM, Bazin MA, Marchand P, da Silva TG, Mendonça Junior FJB.

Curr Top Med Chem. 2019;19(13):1075-1091. doi: 10.2174/1568026619666190621120304.


26th Annual GP2A Medicinal Chemistry Conference & 32nd Journées Franco-Belges de Pharmacochimie.

Dallemagne P, Rochais C, Marchand P, Besson T.

Pharmaceuticals (Basel). 2019 May 16;12(2). pii: E73. doi: 10.3390/ph12020073.


Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition.

Winfield HJ, Cahill MM, O'Shea KD, Pierce LT, Robert T, Ruchaud S, Bach S, Marchand P, McCarthy FO.

Bioorg Med Chem. 2018 Aug 7;26(14):4209-4224. doi: 10.1016/j.bmc.2018.07.012. Epub 2018 Jul 9.


Circadian periodicity in space use by ungulates of temperate regions: How much, when and why?

Péron G, Duparc A, Garel M, Marchand P, Morellet N, Saïd S, Loison A.

J Anim Ecol. 2018 Sep;87(5):1299-1308. doi: 10.1111/1365-2656.12857. Epub 2018 Jul 2.


Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration.

Dao VH, Ourliac-Garnier I, Bazin MA, Jacquot C, Baratte B, Ruchaud S, Bach S, Grovel O, Le Pape P, Marchand P.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2250-2255. doi: 10.1016/j.bmcl.2018.05.044. Epub 2018 May 23.


Introduction history overrides social factors in explaining genetic structure of females in Mediterranean mouflon.

Portanier E, Garel M, Devillard S, Marchand P, Andru J, Maillard D, Bourgoin G.

Ecol Evol. 2017 Nov 16;7(22):9580-9591. doi: 10.1002/ece3.3433. eCollection 2017 Nov.


Sociospatial structure explains marked variation in brucellosis seroprevalence in an Alpine ibex population.

Marchand P, Freycon P, Herbaux JP, Game Y, Toïgo C, Gilot-Fromont E, Rossi S, Hars J.

Sci Rep. 2017 Nov 15;7(1):15592. doi: 10.1038/s41598-017-15803-w.


Integrating Multidisciplinary Results to Produce New Knowledge About the Physician-Patient Relationship: A Methodology Applied to the INTERMEDE Project.

Schieber AC, Kelly-Irving M, Génolini JP, Membrado M, Tanguy L, Fabre C, Marchand P, Lang T; INTERMEDE Group.

J Mix Methods Res. 2017 Apr;11(2):174-201. doi: 10.1177/1558689815588643. Epub 2015 Aug 13.


Fission-fusion dynamics over large distances in raven non-breeders.

Loretto MC, Schuster R, Itty C, Marchand P, Genero F, Bugnyar T.

Sci Rep. 2017 Mar 23;7(1):380. doi: 10.1038/s41598-017-00404-4.


Combining familiarity and landscape features helps break down the barriers between movements and home ranges in a non-territorial large herbivore.

Marchand P, Garel M, Bourgoin G, Duparc A, Dubray D, Maillard D, Loison A.

J Anim Ecol. 2017 Mar;86(2):371-383. doi: 10.1111/1365-2656.12616. Epub 2017 Jan 23.


Characterization of the biochemical, physiological, and medicinal properties of Streptomyces hygroscopicus ACTMS-9H isolated from the Amazon (Brazil).

Lima SM, Melo JG, Militão GC, Lima GM, do Carmo A Lima M, Aguiar JS, Araújo RM, Braz-Filho R, Marchand P, Araújo JM, Silva TG.

Appl Microbiol Biotechnol. 2017 Jan;101(2):711-723. doi: 10.1007/s00253-016-7886-9. Epub 2016 Oct 18.


Discovery of Novel (Imidazo[1,2-a]pyrazin-6-yl)ureas as Antiproliferative Agents Targeting P53 in Non-small Cell Lung Cancer Cell Lines.

Bazin MA, Rousseau B, Marhadour S, Tomasoni C, Evenou P, Piessard S, Vaisberg AJ, Ruchaud S, Bach S, Roussakis C, Marchand P.

Anticancer Res. 2016 Apr;36(4):1621-30.


Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines.

Marchand P, Bazin MA, Pagniez F, Rivière G, Bodero L, Marhadour S, Nourrisson MR, Picot C, Ruchaud S, Bach S, Baratte B, Sauvain M, Pareja DC, Vaisberg AJ, Le Pape P.

Eur J Med Chem. 2015 Oct 20;103:381-95. doi: 10.1016/j.ejmech.2015.09.002. Epub 2015 Sep 9.


Synthesis and molecular modelling studies of 8-arylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors.

Loidreau Y, Deau E, Marchand P, Nourrisson MR, Logé C, Coadou G, Loaëc N, Meijer L, Besson T.

Eur J Med Chem. 2015 Mar 6;92:124-34. doi: 10.1016/j.ejmech.2014.12.038. Epub 2014 Dec 23.


Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells.

Defaux J, Antoine M, Logé C, Le Borgne M, Schuster T, Seipelt I, Aicher B, Teifel M, Günther E, Gerlach M, Marchand P.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3748-52. doi: 10.1016/j.bmcl.2014.06.078. Epub 2014 Jul 3.


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