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Items: 1 to 20 of 64

1.

Gut Microbiota and Fecal Levels of Short-Chain Fatty Acids Differ Upon 24-Hour Blood Pressure Levels in Men.

Huart J, Leenders J, Taminiau B, Descy J, Saint-Remy A, Daube G, Krzesinski JM, Melin P, de Tullio P, Jouret F.

Hypertension. 2019 Oct;74(4):1005-1013. doi: 10.1161/HYPERTENSIONAHA.118.12588. Epub 2019 Jul 29.

PMID:
31352822
2.

Two data pre-processing workflows to facilitate the discovery of biomarkers by 2D NMR metabolomics.

Féraud B, Leenders J, Martineau E, Giraudeau P, Govaerts B, de Tullio P.

Metabolomics. 2019 Apr 16;15(4):63. doi: 10.1007/s11306-019-1524-3.

PMID:
30993405
3.

Death following consumption of MDAI and 5-EAPB.

Deville M, Dubois N, Cieckiewicz E, De Tullio P, Lemaire E, Charlier C.

Forensic Sci Int. 2019 Jun;299:89-94. doi: 10.1016/j.forsciint.2019.03.023. Epub 2019 Mar 25.

PMID:
30981086
4.

Transforming growth factor beta-induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration.

Costanza B, Rademaker G, Tiamiou A, De Tullio P, Leenders J, Blomme A, Bellier J, Bianchi E, Turtoi A, Delvenne P, Bellahcène A, Peulen O, Castronovo V.

Int J Cancer. 2019 Sep 15;145(6):1570-1584. doi: 10.1002/ijc.32247. Epub 2019 Mar 28.

5.

Metabolomics as an Innovative Tool for a Personalised Approach to Vascular Disease.

de Tullio P, Leenders J, Vega de Ceniga M, Chakfé N, Kolh PH.

Eur J Vasc Endovasc Surg. 2019 Mar;57(3):329-330. doi: 10.1016/j.ejvs.2019.01.003. Epub 2019 Feb 1. No abstract available.

PMID:
30718034
6.

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models.

Depetter Y, Geurs S, De Vreese R, Goethals S, Vandoorn E, Laevens A, Steenbrugge J, Meyer E, de Tullio P, Bracke M, D'hooghe M, De Wever O.

Int J Cancer. 2019 Aug 1;145(3):735-747. doi: 10.1002/ijc.32169. Epub 2019 Feb 20.

PMID:
30694564
7.

CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury.

Yakulov TA, Todkar AP, Slanchev K, Wiegel J, Bona A, Groß M, Scholz A, Hess I, Wurditsch A, Grahammer F, Huber TB, Lecaudey V, Bork T, Hochrein J, Boerries M, Leenders J, de Tullio P, Jouret F, Kramer-Zucker A, Walz G.

Nat Commun. 2018 Sep 10;9(1):3660. doi: 10.1038/s41467-018-06094-4.

8.

Codon-specific translation reprogramming promotes resistance to targeted therapy.

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, De Tullio P, Sin O, Shostak K, Schmitz S, Piepers J, Ghesquière B, Karim L, Charloteaux B, Jamart D, Florin A, Lambert C, Rorive A, Jerusalem G, Leucci E, Dewaele M, Vooijs M, Leidel SA, Georges M, Voz M, Peers B, Büttner R, Marine JC, Chariot A, Close P.

Nature. 2018 Jun;558(7711):605-609. doi: 10.1038/s41586-018-0243-7. Epub 2018 Jun 20.

PMID:
29925953
9.

PepsNMR for 1H NMR metabolomic data pre-processing.

Martin M, Legat B, Leenders J, Vanwinsberghe J, Rousseau R, Boulanger B, Eilers PHC, De Tullio P, Govaerts B.

Anal Chim Acta. 2018 Aug 17;1019:1-13. doi: 10.1016/j.aca.2018.02.067. Epub 2018 Mar 12.

PMID:
29625674
10.

"NOTA-PRGD2 and NODAGA-PRGD2 : Bioconjugation, characterization, radiolabelling, and design space".

Salvé M, Avohou HT, Monbaliu JM, Lebrun P, Lemaire C, Damblon C, de Tullio P, Hubert P, Hustinx R, Luxen A.

J Labelled Comp Radiopharm. 2018 May 30;61(6):487-500. doi: 10.1002/jlcr.3613. Epub 2018 Apr 25.

PMID:
29430693
11.

7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency.

Goffin E, Drapier T, Larsen AP, Geubelle P, Ptak CP, Laulumaa S, Rovinskaja K, Gilissen J, Tullio P, Olsen L, Frydenvang K, Pirotte B, Hanson J, Oswald RE, Kastrup JS, Francotte P.

J Med Chem. 2018 Jan 11;61(1):251-264. doi: 10.1021/acs.jmedchem.7b01323. Epub 2017 Dec 19.

12.

Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.

Tommelein J, De Vlieghere E, Verset L, Melsens E, Leenders J, Descamps B, Debucquoy A, Vanhove C, Pauwels P, Gespach CP, Vral A, De Boeck A, Haustermans K, de Tullio P, Ceelen W, Demetter P, Boterberg T, Bracke M, De Wever O.

Cancer Res. 2018 Feb 1;78(3):659-670. doi: 10.1158/0008-5472.CAN-17-0524. Epub 2017 Dec 7.

13.

31ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report.

Frédérick R, Pochet L, De Tullio P, Dufrasne F.

Pharmaceuticals (Basel). 2017 Dec 4;10(4). pii: E94. doi: 10.3390/ph10040094.

14.

Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

Schnekenburger M, Goffin E, Lee JY, Jang JY, Mazumder A, Ji S, Rogister B, Bouider N, Lefranc F, Miklos W, Mathieu V, de Tullio P, Kim KW, Dicato M, Berger W, Han BW, Kiss R, Pirotte B, Diederich M.

J Med Chem. 2017 Jun 8;60(11):4714-4733. doi: 10.1021/acs.jmedchem.7b00533. Epub 2017 May 25.

15.

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.

Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A.

Elife. 2016 Oct 19;5. pii: e19375. doi: 10.7554/eLife.19375.

16.

Nuclear Magnetic Resonance Metabolomic Profiling of Mouse Kidney, Urine and Serum Following Renal Ischemia/Reperfusion Injury.

Jouret F, Leenders J, Poma L, Defraigne JO, Krzesinski JM, de Tullio P.

PLoS One. 2016 Sep 22;11(9):e0163021. doi: 10.1371/journal.pone.0163021. eCollection 2016.

17.

Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine.

Frédérich M, Pirotte B, Fillet M, de Tullio P.

J Med Chem. 2016 Oct 13;59(19):8649-8666. Epub 2016 Jun 27.

PMID:
27295417
18.

4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky 'carbamate' moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion.

Pirotte B, Florence X, Goffin E, Medeiros MB, de Tullio P, Lebrun P.

Eur J Med Chem. 2016 Oct 4;121:338-351. doi: 10.1016/j.ejmech.2016.05.042. Epub 2016 May 24.

PMID:
27267004
19.

Synthesis, characterization and biological evaluation of benzothiazoles and tetrahydrobenzothiazoles bearing urea or thiourea moieties as vasorelaxants and inhibitors of the insulin releasing process.

Harrouche K, Renard JF, Bouider N, de Tullio P, Goffin E, Lebrun P, Faury G, Pirotte B, Khelili S.

Eur J Med Chem. 2016 Jun 10;115:352-60. doi: 10.1016/j.ejmech.2016.03.028. Epub 2016 Mar 12.

PMID:
27031211
20.

Interest of cyclodextrins in spray-dried microparticles formulation for sustained pulmonary delivery of budesonide.

Dufour G, Bigazzi W, Wong N, Boschini F, de Tullio P, Piel G, Cataldo D, Evrard B.

Int J Pharm. 2015 Nov 30;495(2):869-78. doi: 10.1016/j.ijpharm.2015.09.052. Epub 2015 Sep 26.

PMID:
26410753

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