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Items: 1 to 20 of 36


The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously Targets HIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs.

Gerlach SL, Chandra PK, Roy U, Gunasekera S, Göransson U, Wimley WC, Braun SE, Mondal D.

Medicines (Basel). 2019 Feb 28;6(1). pii: E33. doi: 10.3390/medicines6010033.


Mesenchymal stem cells are attracted to latent HIV-1-infected cells and enable virus reactivation via a non-canonical PI3K-NFκB signaling pathway.

Chandra PK, Gerlach SL, Wu C, Khurana N, Swientoniewski LT, Abdel-Mageed AB, Li J, Braun SE, Mondal D.

Sci Rep. 2018 Oct 2;8(1):14702. doi: 10.1038/s41598-018-32657-y.


Interferon-alpha-induced hepatitis C virus clearance restores p53 tumor suppressor more than direct-acting antivirals.

Aydin Y, Chatterjee A, Chandra PK, Chava S, Chen W, Tandon A, Dash A, Chedid M, Moehlen MW, Regenstein F, Balart LA, Cohen A, Lu H, Wu T, Dash S.

Hepatol Commun. 2017 Mar 28;1(3):256-269. doi: 10.1002/hep4.1025. eCollection 2017 May.


Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer.

Khurana N, Kim H, Chandra PK, Talwar S, Sharma P, Abdel-Mageed AB, Sikka SC, Mondal D.

Oncol Rep. 2017 Nov;38(5):2774-2786. doi: 10.3892/or.2017.5932. Epub 2017 Aug 30.


Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma.

Chava S, Lee C, Aydin Y, Chandra PK, Dash A, Chedid M, Thung SN, Moroz K, Wu T, Nayak NC, Dash S.

Oncotarget. 2017 Jun 20;8(25):40019-40036. doi: 10.18632/oncotarget.16685.


Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells.

Khurana N, Talwar S, Chandra PK, Sharma P, Abdel-Mageed AB, Mondal D, Sikka SC.

Int J Oncol. 2016 Oct;49(4):1609-19. doi: 10.3892/ijo.2016.3641. Epub 2016 Aug 2.


Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response.

Dash S, Chava S, Aydin Y, Chandra PK, Ferraris P, Chen W, Balart LA, Wu T, Garry RF.

Viruses. 2016 May 23;8(5). pii: E150. doi: 10.3390/v8050150. Review.


Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response.

Dash S, Chava S, Chandra PK, Aydin Y, Balart LA, Wu T.

Hepat Med. 2016 Feb 22;8:9-20. doi: 10.2147/HMER.S63700. eCollection 2016. Review.


Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.

Ferraris P, Chandra PK, Panigrahi R, Aboulnasr F, Chava S, Kurt R, Pawlotsky JM, Wilkens L, Osterlund P, Hartmann R, Balart LA, Wu T, Dash S.

Am J Pathol. 2016 Apr;186(4):938-51. doi: 10.1016/j.ajpath.2015.11.027. Epub 2016 Feb 16.


Tripping on TRIB3 at the junction of health, metabolic dysfunction and cancer.

Mondal D, Mathur A, Chandra PK.

Biochimie. 2016 May;124:34-52. doi: 10.1016/j.biochi.2016.02.005. Epub 2016 Feb 6. Review.


IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System.

Aboulnasr F, Hazari S, Nayak S, Chandra PK, Panigrahi R, Ferraris P, Chava S, Kurt R, Song K, Dash A, Balart LA, Garry RF, Wu T, Dash S.

PLoS One. 2015 Dec 11;10(12):e0141655. doi: 10.1371/journal.pone.0141655. eCollection 2015.


Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Kurt R, Chandra PK, Aboulnasr F, Panigrahi R, Ferraris P, Aydin Y, Reiss K, Wu T, Balart LA, Dash S.

PLoS One. 2015 May 11;10(5):e0125962. doi: 10.1371/journal.pone.0125962. eCollection 2015.


Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1.

Panigrahi R, Chandra PK, Ferraris P, Kurt R, Song K, Garry RF, Reiss K, Coe IR, Furihata T, Balart LA, Wu T, Dash S.

J Virol. 2015 Jan;89(1):626-42. doi: 10.1128/JVI.02492-14. Epub 2014 Oct 22.


Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

Chandra PK, Gunduz F, Hazari S, Kurt R, Panigrahi R, Poat B, Bruce D, Cohen AJ, Bohorquez HE, Carmody I, Loss G, Balart LA, Wu T, Dash S.

PLoS One. 2014 Sep 29;9(9):e108616. doi: 10.1371/journal.pone.0108616. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114456. Behorquez, Humberto E [corrected to Bohorquez, Humberto E].


Impaired autophagy response in human hepatocellular carcinoma.

Bao L, Chandra PK, Moroz K, Zhang X, Thung SN, Wu T, Dash S.

Exp Mol Pathol. 2014 Apr;96(2):149-54. doi: 10.1016/j.yexmp.2013.12.002. Epub 2013 Dec 23.


HCV infection selectively impairs type I but not type III IFN signaling.

Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S.

Am J Pathol. 2014 Jan;184(1):214-29. doi: 10.1016/j.ajpath.2013.10.005. Epub 2013 Nov 9.


Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation.

Panigrahi R, Hazari S, Chandra S, Chandra PK, Datta S, Kurt R, Cameron CE, Huang Z, Zhang H, Garry RF, Balart LA, Dash S.

PLoS One. 2013 Aug 23;8(8):e72791. doi: 10.1371/journal.pone.0072791. eCollection 2013.


Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture.

Gunduz F, Aboulnasr FM, Chandra PK, Hazari S, Poat B, Baker DP, Balart LA, Dash S.

Virol J. 2012 Aug 3;9:143. doi: 10.1186/1743-422X-9-143.


Inhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes.

Chandra PK, Kundu AK, Hazari S, Chandra S, Bao L, Ooms T, Morris GF, Wu T, Mandal TK, Dash S.

Mol Ther. 2012 Sep;20(9):1724-36. doi: 10.1038/mt.2012.107. Epub 2012 May 22.


Stability of lyophilized siRNA nanosome formulations.

Kundu AK, Chandra PK, Hazari S, Ledet G, Pramar YV, Dash S, Mandal TK.

Int J Pharm. 2012 Feb 28;423(2):525-34. doi: 10.1016/j.ijpharm.2011.11.040. Epub 2011 Dec 6.

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