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Items: 1 to 20 of 42

1.

Retinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in APL cells.

Huynh TT, Sultan M, Vidovic D, Dean CA, Cruickshank BM, Lee K, Loung CY, Holloway RW, Hoskin DW, Waisman DM, Weaver ICG, Marcato P.

Sci Rep. 2019 Jul 1;9(1):9414. doi: 10.1038/s41598-019-45982-7.

2.

ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells.

Vidovic D, Huynh TT, Konda P, Dean C, Cruickshank BM, Sultan M, Coyle KM, Gujar S, Marcato P.

Cell Death Differ. 2019 Jun 13. doi: 10.1038/s41418-019-0362-1. [Epub ahead of print]

PMID:
31197235
3.

TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway.

Almasi S, Sterea AM, Fernando W, Clements DR, Marcato P, Hoskin DW, Gujar S, El Hiani Y.

Sci Rep. 2019 Mar 12;9(1):4182. doi: 10.1038/s41598-019-40330-1.

4.

TAp73 Modifies Metabolism and Positively Regulates Growth of Cancer Stem-Like Cells in a Redox-Sensitive Manner.

Sharif T, Dai C, Martell E, Ghassemi-Rad MS, Hanes MR, Murphy PJ, Kennedy BE, Venugopal C, Subapanditha M, Giacomantonio CA, Marcato P, Singh SK, Gujar S.

Clin Cancer Res. 2019 Mar 15;25(6):2001-2017. doi: 10.1158/1078-0432.CCR-17-3177. Epub 2018 Dec 28.

PMID:
30593514
5.

DNA Methylation Predicts the Response of Triple-Negative Breast Cancers to All-Trans Retinoic Acid.

Coyle KM, Dean CA, Thomas ML, Vidovic D, Giacomantonio CA, Helyer L, Marcato P.

Cancers (Basel). 2018 Oct 24;10(11). pii: E397. doi: 10.3390/cancers10110397.

6.

Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL).

Holloway RW, Thomas ML, Cohen AM, Bharadwaj AG, Rahman M, Marcato P, Marignani PA, Waisman DM.

Cell Death Dis. 2018 Sep 11;9(9):920. doi: 10.1038/s41419-018-0954-6.

7.

ALDH1A3 Is the Key Isoform That Contributes to Aldehyde Dehydrogenase Activity and Affects in Vitro Proliferation in Cardiac Atrial Appendage Progenitor Cells.

Puttini S, Plaisance I, Barile L, Cervio E, Milano G, Marcato P, Pedrazzini T, Vassalli G.

Front Cardiovasc Med. 2018 Jul 24;5:90. doi: 10.3389/fcvm.2018.00090. eCollection 2018.

8.

Dying to Be Noticed: Epigenetic Regulation of Immunogenic Cell Death for Cancer Immunotherapy.

Cruickshank B, Giacomantonio M, Marcato P, McFarland S, Pol J, Gujar S.

Front Immunol. 2018 Apr 3;9:654. doi: 10.3389/fimmu.2018.00654. eCollection 2018. Review.

9.

Epigenetic Modifications as Biomarkers of Tumor Development, Therapy Response, and Recurrence across the Cancer Care Continuum.

Thomas ML, Marcato P.

Cancers (Basel). 2018 Apr 1;10(4). pii: E101. doi: 10.3390/cancers10040101. Review.

10.

Epigenetic Silencing of TAP1 in Aldefluor+ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion.

Sultan M, Vidovic D, Paine AS, Huynh TT, Coyle KM, Thomas ML, Cruickshank BM, Dean CA, Clements DR, Kim Y, Lee K, Gujar SA, Weaver ICG, Marcato P.

Stem Cells. 2018 May;36(5):641-654. doi: 10.1002/stem.2780. Epub 2018 Jan 30.

11.

Profiling of the transcriptional response to all-trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression.

Coyle KM, Maxwell S, Thomas ML, Marcato P.

Sci Rep. 2017 Nov 30;7(1):16684. doi: 10.1038/s41598-017-16687-6.

12.

Genetic Mutations and Epigenetic Modifications: Driving Cancer and Informing Precision Medicine.

Coyle KM, Boudreau JE, Marcato P.

Biomed Res Int. 2017;2017:9620870. doi: 10.1155/2017/9620870. Epub 2017 Jun 8. Review.

13.

Hide-and-seek: the interplay between cancer stem cells and the immune system.

Sultan M, Coyle KM, Vidovic D, Thomas ML, Gujar S, Marcato P.

Carcinogenesis. 2017 Feb 1;38(2):107-118. doi: 10.1093/carcin/bgw115. Review.

PMID:
27866156
14.

Citral reduces breast tumor growth by inhibiting the cancer stem cell marker ALDH1A3.

Thomas ML, de Antueno R, Coyle KM, Sultan M, Cruickshank BM, Giacomantonio MA, Giacomantonio CA, Duncan R, Marcato P.

Mol Oncol. 2016 Nov;10(9):1485-1496. doi: 10.1016/j.molonc.2016.08.004. Epub 2016 Aug 25.

15.

Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1.

Coyle KM, Murphy JP, Vidovic D, Vaghar-Kashani A, Dean CA, Sultan M, Clements D, Wallace M, Thomas ML, Hundert A, Giacomantonio CA, Helyer L, Gujar SA, Lee PW, Weaver IC, Marcato P.

Oncotarget. 2016 Jul 12;7(28):44096-44112. doi: 10.18632/oncotarget.9858.

16.

A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations.

Canino C, Luo Y, Marcato P, Blandino G, Pass HI, Cioce M.

Oncotarget. 2015 May 20;6(14):12637-53.

17.

Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus.

Clements DR, Sterea AM, Kim Y, Helson E, Dean CA, Nunokawa A, Coyle KM, Sharif T, Marcato P, Gujar SA, Lee PW.

J Immunol. 2015 May 1;194(9):4397-412. doi: 10.4049/jimmunol.1402132. Epub 2015 Mar 30.

18.

Core needle biopsy of breast cancer tumors increases distant metastases in a mouse model.

Mathenge EG, Dean CA, Clements D, Vaghar-Kashani A, Photopoulos S, Coyle KM, Giacomantonio M, Malueth B, Nunokawa A, Jordan J, Lewis JD, Gujar SA, Marcato P, Lee PW, Giacomantonio CA.

Neoplasia. 2014 Nov 20;16(11):950-60. doi: 10.1016/j.neo.2014.09.004. eCollection 2014 Nov.

19.

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling.

Marcato P, Dean CA, Liu RZ, Coyle KM, Bydoun M, Wallace M, Clements D, Turner C, Mathenge EG, Gujar SA, Giacomantonio CA, Mackey JR, Godbout R, Lee PW.

Mol Oncol. 2015 Jan;9(1):17-31. doi: 10.1016/j.molonc.2014.07.010. Epub 2014 Jul 24.

20.

Activation of p53 by chemotherapeutic agents enhances reovirus oncolysis.

Pan D, Marcato P, Ahn DG, Gujar S, Pan LZ, Shmulevitz M, Lee PW.

PLoS One. 2013;8(1):e54006. doi: 10.1371/journal.pone.0054006. Epub 2013 Jan 16.

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