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Items: 1 to 20 of 37


A Comprehensive Superposition of Viral Polymerase Structures.

Peersen OB.

Viruses. 2019 Aug 13;11(8). pii: E745. doi: 10.3390/v11080745. Review.


Picornavirus RNA Recombination Counteracts Error Catastrophe.

Kempf BJ, Watkins CL, Peersen OB, Barton DJ.

J Virol. 2019 Jun 28;93(14). pii: e00652-19. doi: 10.1128/JVI.00652-19. Print 2019 Jul 15.


Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine.

Martínez-Sobrido L, Peersen O, Nogales A.

Viruses. 2018 Oct 15;10(10). pii: E560. doi: 10.3390/v10100560. Review.


Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics.

DeLuca KF, Meppelink A, Broad AJ, Mick JE, Peersen OB, Pektas S, Lens SMA, DeLuca JG.

J Cell Biol. 2018 Jan 2;217(1):163-177. doi: 10.1083/jcb.201707160. Epub 2017 Nov 29.


Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis.

Farrell KB, McDonald S, Lamb AK, Worcester C, Peersen OB, Di Pietro SM.

J Cell Biol. 2017 Aug 7;216(8):2565-2580. doi: 10.1083/jcb.201604123. Epub 2017 Jul 13.


Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.

Rai DK, Diaz-San Segundo F, Campagnola G, Keith A, Schafer EA, Kloc A, de Los Santos T, Peersen O, Rieder E.

J Virol. 2017 Jul 12;91(15). pii: e00081-17. doi: 10.1128/JVI.00081-17. Print 2017 Aug 1.


Picornaviral polymerase structure, function, and fidelity modulation.

Peersen OB.

Virus Res. 2017 Apr 15;234:4-20. doi: 10.1016/j.virusres.2017.01.026. Epub 2017 Feb 2. Review.


Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance.

Kempf BJ, Peersen OB, Barton DJ.

J Virol. 2016 Sep 12;90(19):8410-21. doi: 10.1128/JVI.00078-16. Print 2016 Oct 1.


Peptide Synthesis on a Next-Generation DNA Sequencing Platform.

Svensen N, Peersen OB, Jaffrey SR.

Chembiochem. 2016 Sep 2;17(17):1628-35. doi: 10.1002/cbic.201600298. Epub 2016 Jul 6.


ATP Is an Allosteric Inhibitor of Coxsackievirus B3 Polymerase.

Karr JP, Peersen OB.

Biochemistry. 2016 Jul 19;55(28):3995-4002. doi: 10.1021/acs.biochem.6b00467. Epub 2016 Jul 6.


Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.

Sexton NR, Smith EC, Blanc H, Vignuzzi M, Peersen OB, Denison MR.

J Virol. 2016 Jul 27;90(16):7415-7428. doi: 10.1128/JVI.00080-16. Print 2016 Aug 15.


Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.

McDonald S, Block A, Beaucourt S, Moratorio G, Vignuzzi M, Peersen OB.

J Biol Chem. 2016 Jul 1;291(27):13999-4011. doi: 10.1074/jbc.M116.726596. Epub 2016 May 2.


Strange kinetics of bulk-mediated diffusion on lipid bilayers.

Krapf D, Campagnola G, Nepal K, Peersen OB.

Phys Chem Chem Phys. 2016 May 14;18(18):12633-41. doi: 10.1039/c6cp00937a. Epub 2016 Apr 20.


Superdiffusive motion of membrane-targeting C2 domains.

Campagnola G, Nepal K, Schroder BW, Peersen OB, Krapf D.

Sci Rep. 2015 Dec 7;5:17721. doi: 10.1038/srep17721.


Editorial overview: Virus replication in animals and plants.

Kao CC, Peersen OB.

Curr Opin Virol. 2014 Dec;9:iv-v. doi: 10.1016/j.coviro.2014.10.002. Epub 2014 Oct 30. No abstract available.


Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases.

Campagnola G, McDonald S, Beaucourt S, Vignuzzi M, Peersen OB.

J Virol. 2015 Jan;89(1):275-86. doi: 10.1128/JVI.01574-14. Epub 2014 Oct 15.


Distinct conformations of a putative translocation element in poliovirus polymerase.

Sholders AJ, Peersen OB.

J Mol Biol. 2014 Apr 3;426(7):1407-19. doi: 10.1016/j.jmb.2013.12.031. Epub 2014 Jan 12.


Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.

Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB.

PLoS One. 2013 May 8;8(5):e60272. doi: 10.1371/journal.pone.0060272. Print 2013.


Polyprotein context regulates the activity of poliovirus 2CATPase bound to bilayer nanodiscs.

Springer CL, Huntoon HP, Peersen OB.

J Virol. 2013 May;87(10):5994-6004. doi: 10.1128/JVI.03491-12. Epub 2013 Mar 20.


Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA.

Kempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJ.

J Virol. 2013 May;87(10):5629-44. doi: 10.1128/JVI.02590-12. Epub 2013 Mar 6.

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