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Items: 1 to 20 of 42

1.

Reactive oxygen species (ROS)-responsive polymersomes with site-specific chemotherapeutic delivery into tumors via spacer design chemistry.

Jager E, Sincari V, Albuquerque LJC, Jager A, Humajova J, Kucka J, Pankrac J, Paral P, Heizer T, Janoušková O, Konefal R, Pavlova E, Sedlacek O, Giacomelli FC, Pouckova P, Sefc L, Stepanek P, Hruby M.

Biomacromolecules. 2020 Feb 21. doi: 10.1021/acs.biomac.9b01748. [Epub ahead of print]

PMID:
32083473
2.

Molecular Mechanisms of the Interactions of N-(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins.

Janisova L, Gruzinov A, Zaborova OV, Velychkivska N, Vaněk O, Chytil P, Etrych T, Janoušková O, Zhang X, Blanchet C, Papadakis CM, Svergun DI, Filippov SK.

Pharmaceutics. 2020 Jan 28;12(2). pii: E106. doi: 10.3390/pharmaceutics12020106.

3.

Polymer Cancerostatics Containing Cell-Penetrating Peptides: Internalization Efficacy Depends on Peptide Type and Spacer Length.

Böhmová E, Pola R, Pechar M, Parnica J, Machová D, Janoušková O, Etrych T.

Pharmaceutics. 2020 Jan 10;12(1). pii: E59. doi: 10.3390/pharmaceutics12010059.

4.

Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors.

Pola R, Böhmová E, Filipová M, Pechar M, Pankrác J, Větvička D, Olejár T, Kabešová M, Poučková P, Šefc L, Zábrodský M, Janoušková O, Bouček J, Etrych T.

Pharmaceutics. 2020 Jan 1;12(1). pii: E31. doi: 10.3390/pharmaceutics12010031.

5.

Fluorescence Imaging as a Tool in Preclinical Evaluation of Polymer-Based Nano-DDS Systems Intended for Cancer Treatment.

Etrych T, Janoušková O, Chytil P.

Pharmaceutics. 2019 Sep 12;11(9). pii: E471. doi: 10.3390/pharmaceutics11090471. Review.

6.

Biomimetic modification of dual porosity poly(2-hydroxyethyl methacrylate) hydrogel scaffolds-porosity and stem cell growth evaluation.

Janoušková O, Přádný M, Vetrík M, Chylíková Krumbholcová E, Michálek J, Dušková Smrčková M.

Biomed Mater. 2019 Jul 15;14(5):055004. doi: 10.1088/1748-605X/ab2856.

PMID:
31181551
7.

Enhanced solid phase extraction of DNA using hydrophilic monodisperse poly(methacrylic acid-co-ethylene dimethacrylate) microparticles.

Šálek P, Filipová M, Horák D, Proks V, Janoušková O.

Mol Biol Rep. 2019 Jun;46(3):3063-3072. doi: 10.1007/s11033-019-04742-6. Epub 2019 Mar 11.

PMID:
30859448
8.

Microparticles of Lamivudine-Poly-ε-Caprolactone Conjugate for Drug Delivery via Internalization by Macrophages.

Urbaniak T, Machová D, Janoušková O, Musiał W.

Molecules. 2019 Feb 17;24(4). pii: E723. doi: 10.3390/molecules24040723.

9.

Preparation of membrane-mimicking lamellar structures by molecular confinement of hybrid nanocomposites.

Vrbata D, Ďorďovič V, Seitsonen J, Ruokolainen J, Janoušková O, Uchman M, Matějíček P.

Chem Commun (Camb). 2019 Mar 5;55(20):2900-2903. doi: 10.1039/c8cc09399g.

PMID:
30698594
10.

The Effect of iPS-Derived Neural Progenitors Seeded on Laminin-Coated pHEMA-MOETACl Hydrogel with Dual Porosity in a Rat Model of Chronic Spinal Cord Injury.

Ruzicka J, Romanyuk N, Jirakova K, Hejcl A, Janouskova O, Machova LU, Bochin M, Pradny M, Vargova L, Jendelova P.

Cell Transplant. 2019 Apr;28(4):400-412. doi: 10.1177/0963689718823705. Epub 2019 Jan 18.

11.

Straightforward Route to Superhydrophilic Poly(2-oxazoline)s via Acylation of Well-Defined Polyethylenimine.

Sedlacek O, Janouskova O, Verbraeken B, Hoogenboom R.

Biomacromolecules. 2019 Jan 14;20(1):222-230. doi: 10.1021/acs.biomac.8b01366. Epub 2018 Dec 10.

PMID:
30512933
12.

Nanotherapeutics with suitable properties for advanced anticancer therapy based on HPMA copolymer-bound ritonavir via pH-sensitive spacers.

Machová D, Koziolová E, Chytil P, Venclíková K, Etrych T, Janoušková O.

Eur J Pharm Biopharm. 2018 Oct;131:141-150. doi: 10.1016/j.ejpb.2018.07.023. Epub 2018 Jul 31.

PMID:
30075311
13.

Self-Assembled Thermoresponsive Polymeric Nanogels for 19F MR Imaging.

Kolouchova K, Sedlacek O, Jirak D, Babuka D, Blahut J, Kotek J, Vit M, Trousil J, Konefał R, Janouskova O, Podhorska B, Slouf M, Hruby M.

Biomacromolecules. 2018 Aug 13;19(8):3515-3524. doi: 10.1021/acs.biomac.8b00812. Epub 2018 Jul 27.

PMID:
30011367
14.

Paclitaxel-Loaded Polylactide/Polyethylene Glycol Fibers with Long-Term Antitumor Activity as a Potential Drug Carrier for Local Chemotherapy.

Plch J, Venclikova K, Janouskova O, Hrabeta J, Eckschlager T, Kopeckova K, Hampejsova Z, Bosakova Z, Sirc J, Hobzova R.

Macromol Biosci. 2018 Jun;18(6):e1800011. doi: 10.1002/mabi.201800011. Epub 2018 Apr 24.

PMID:
29688614
15.

Iterative Photoinduced Chain Functionalization as a Generic Platform for Advanced Polymeric Drug Delivery Systems.

Samad AA, Bethry A, Janouskova O, Ciccione J, Wenk C, Coll JL, Subra G, Etrych T, Omar FE, Bakkour Y, Coudane J, Nottelet B.

Macromol Rapid Commun. 2018 Feb;39(3). doi: 10.1002/marc.201700502. Epub 2017 Nov 2.

PMID:
29094415
16.

A simple neridronate-based surface coating strategy for upconversion nanoparticles: highly colloidally stable 125I-radiolabeled NaYF4:Yb3+/Er3+@PEG nanoparticles for multimodal in vivo tissue imaging.

Kostiv U, Lobaz V, Kučka J, Švec P, Sedláček O, Hrubý M, Janoušková O, Francová P, Kolářová V, Šefc L, Horák D.

Nanoscale. 2017 Nov 9;9(43):16680-16688. doi: 10.1039/c7nr05456d.

PMID:
29067394
17.

Thermoresponsive β-glucan-based polymers for bimodal immunoradiotherapy - Are they able to promote the immune system?

Loukotová L, Kučka J, Rabyk M, Höcherl A, Venclíková K, Janoušková O, Páral P, Kolářová V, Heizer T, Šefc L, Štěpánek P, Hrubý M.

J Control Release. 2017 Dec 28;268:78-91. doi: 10.1016/j.jconrel.2017.10.010. Epub 2017 Oct 12.

PMID:
29031896
18.

Polymer Cancerostatics Targeted with an Antibody Fragment Bound via a Coiled Coil Motif: In Vivo Therapeutic Efficacy against Murine BCL1 Leukemia.

Pechar M, Pola R, Janoušková O, Sieglová I, Král V, Fábry M, Tomalová B, Kovář M.

Macromol Biosci. 2018 Jan;18(1). doi: 10.1002/mabi.201700173. Epub 2017 Sep 15.

PMID:
28921867
19.

Ability of polymer-bound P-glycoprotein inhibitor ritonavir to overcome multidrug resistance in various resistant neuroblastoma cell lines.

Koziolová E, Chytil P, Etrych T, Janoušková O.

Anticancer Drugs. 2017 Nov;28(10):1126-1130. doi: 10.1097/CAD.0000000000000553.

PMID:
28901962
20.

Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues.

Sedlacek O, Monnery BD, Mattova J, Kucka J, Panek J, Janouskova O, Hocherl A, Verbraeken B, Vergaelen M, Zadinova M, Hoogenboom R, Hruby M.

Biomaterials. 2017 Nov;146:1-12. doi: 10.1016/j.biomaterials.2017.09.003. Epub 2017 Sep 6.

PMID:
28892751

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