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Items: 1 to 20 of 79

1.

DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling.

Krumkacheva OA, Shevelev GY, Lomzov AA, Dyrkheeva NS, Kuzhelev AA, Koval VV, Tormyshev VM, Polienko YF, Fedin MV, Pyshnyi DV, Lavrik OI, Bagryanskaya EG.

Nucleic Acids Res. 2019 Jul 22. pii: gkz620. doi: 10.1093/nar/gkz620. [Epub ahead of print]

PMID:
31329919
2.

Double-Stranded DNA Fragments Bearing Unrepairable Lesions and Their Internalization into Mouse Krebs-2 Carcinoma Cells.

Dolgova EV, Evdokimov AN, Proskurina AS, Efremov YR, Bayborodin SI, Potter EA, Popov AA, Petruseva IO, Lavrik OI, Bogachev SS.

Nucleic Acid Ther. 2019 Jun 13. doi: 10.1089/nat.2019.0786. [Epub ahead of print]

PMID:
31194620
3.

A Single-Molecule Atomic Force Microscopy Study of PARP1 and PARP2 Recognition of Base Excision Repair DNA Intermediates.

Sukhanova MV, Hamon L, Kutuzov MM, Joshi V, Abrakhi S, Dobra I, Curmi PA, Pastre D, Lavrik OI.

J Mol Biol. 2019 Jul 12;431(15):2655-2673. doi: 10.1016/j.jmb.2019.05.028. Epub 2019 May 23.

PMID:
31129062
4.

Poly(ADP-ribosyl)ation and DNA repair synthesis in the extracts of naked mole rat, mouse, and human cells.

Kosova AA, Kutuzov MM, Evdokimov AN, Ilina ES, Belousova EA, Romanenko SA, Trifonov VA, Khodyreva SN, Lavrik OI.

Aging (Albany NY). 2019 May 13;11(9):2852-2873. doi: 10.18632/aging.101959.

5.

PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA.

Singatulina AS, Hamon L, Sukhanova MV, Desforges B, Joshi V, Bouhss A, Lavrik OI, Pastré D.

Cell Rep. 2019 May 7;27(6):1809-1821.e5. doi: 10.1016/j.celrep.2019.04.031.

6.

Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins.

Alemasova EE, Lavrik OI.

Nucleic Acids Res. 2019 May 7;47(8):3811-3827. doi: 10.1093/nar/gkz120.

7.

Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments.

Mozhaitsev ES, Zakharenko AL, Suslov EV, Korchagina DV, Zakharova OD, Vasil'eva IA, Chepanova AA, Black E, Patel J, Chand R, Reynisson J, Leung IKH, Volcho KP, Salakhutdinov NF, Lavrik OI.

Anticancer Agents Med Chem. 2019;19(4):463-472. doi: 10.2174/1871520619666181207094243.

PMID:
30523770
8.

Dynamic light scattering study of base excision DNA repair proteins and their complexes.

Vasil'eva IA, Anarbaev RO, Moor NA, Lavrik OI.

Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):297-305. doi: 10.1016/j.bbapap.2018.10.009. Epub 2018 Oct 12.

PMID:
30321662
9.

Replication protein A as a modulator of the poly(ADP-ribose)polymerase 1 activity.

Maltseva EA, Krasikova YS, Sukhanova MV, Rechkunova NI, Lavrik OI.

DNA Repair (Amst). 2018 Dec;72:28-38. doi: 10.1016/j.dnarep.2018.09.010. Epub 2018 Sep 24.

PMID:
30291044
10.

A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold.

Li-Zhulanov NS, Zakharenko AL, Chepanova AA, Patel J, Zafar A, Volcho KP, Salakhutdinov NF, Reynisson J, Leung IKH, Lavrik OI.

Molecules. 2018 Sep 26;23(10). pii: E2468. doi: 10.3390/molecules23102468.

11.

Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy.

Komarova AO, Drenichev MS, Dyrkheeva NS, Kulikova IV, Oslovsky VE, Zakharova OD, Zakharenko AL, Mikhailov SN, Lavrik OI.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1415-1429. doi: 10.1080/14756366.2018.1509210.

12.

In vitro lesion bypass by human PrimPol.

Makarova AV, Boldinova EO, Belousova EA, Lavrik OI.

DNA Repair (Amst). 2018 Oct;70:18-24. doi: 10.1016/j.dnarep.2018.07.009. Epub 2018 Jul 27.

PMID:
30098578
13.

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors.

Alemasova EE, Naumenko KN, Kurgina TA, Anarbaev RO, Lavrik OI.

Oncotarget. 2018 May 4;9(34):23349-23365. doi: 10.18632/oncotarget.25158. eCollection 2018 May 4.

14.

Unusual interaction of human apurinic/apyrimidinic endonuclease 1 (APE1) with abasic sites via the Schiff-base-dependent mechanism.

Ilina ES, Khodyreva SN, Lavrik OI.

Biochimie. 2018 Jul;150:88-99. doi: 10.1016/j.biochi.2018.04.027. Epub 2018 May 3.

PMID:
29730300
15.

Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.

Salomatina OV, Popadyuk II, Zakharenko AL, Zakharova OD, Fadeev DS, Komarova NI, Reynisson J, Arabshahi HJ, Chand R, Volcho KP, Salakhutdinov NF, Lavrik OI.

Molecules. 2018 Mar 17;23(3). pii: E679. doi: 10.3390/molecules23030679.

16.

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation.

Zarkovic G, Belousova EA, Talhaoui I, Saint-Pierre C, Kutuzov MM, Matkarimov BT, Biard D, Gasparutto D, Lavrik OI, Ishchenko AA.

Nucleic Acids Res. 2018 Mar 16;46(5):2417-2431. doi: 10.1093/nar/gkx1318.

17.

RPA and XPA interaction with DNA structures mimicking intermediates of the late stages in nucleotide excision repair.

Krasikova YS, Rechkunova NI, Maltseva EA, Lavrik OI.

PLoS One. 2018 Jan 10;13(1):e0190782. doi: 10.1371/journal.pone.0190782. eCollection 2018.

18.

Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors.

Ponomarev KY, Suslov EV, Zakharenko AL, Zakharova OD, Rogachev AD, Korchagina DV, Zafar A, Reynisson J, Nefedov AA, Volcho KP, Salakhutdinov NF, Lavrik OI.

Bioorg Chem. 2018 Feb;76:392-399. doi: 10.1016/j.bioorg.2017.12.005. Epub 2017 Dec 9.

PMID:
29248742
19.

Structural basis for the recognition and processing of DNA containing bulky lesions by the mammalian nucleotide excision repair system.

Evdokimov AN, Tsidulko AY, Popov AV, Vorobiev YN, Lomzov AA, Koroleva LS, Silnikov VN, Petruseva IO, Lavrik OI.

DNA Repair (Amst). 2018 Jan;61:86-98. doi: 10.1016/j.dnarep.2017.10.010. Epub 2017 Nov 2.

PMID:
29103991
20.

The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.

Beletsky AV, Malyavko AN, Sukhanova MV, Mardanova ES, Zvereva MI, Petrova OA, Parfenova YY, Rubtsova MP, Mardanov AV, Lavrik OI, Dontsova OA, Ravin NV.

BMC Genomics. 2017 Jun 28;18(1):492. doi: 10.1186/s12864-017-3889-x.

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