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Items: 1 to 20 of 24

1.

Studying the progression of amyloid pathology and its therapy using translational longitudinal model of accumulation and distribution of amyloid beta.

Karelina T, Demin O, Demin O, Duvvuri S, Nicholas T.

CPT Pharmacometrics Syst Pharmacol. 2017 Sep 15. doi: 10.1002/psp4.12249. [Epub ahead of print]

PMID:
28913897
2.

Comprehensive study of the drug delivery properties of poly(l-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice.

Shalgunov V, Zaytseva-Zotova D, Zintchenko A, Levada T, Shilov Y, Andreyev D, Dzhumashev D, Metelkin E, Urusova A, Demin O, McDonnell K, Troiano G, Zale S, Safarovа E.

J Control Release. 2017 Sep 10;261:31-42. doi: 10.1016/j.jconrel.2017.06.006. Epub 2017 Jun 10.

3.

Prediction of long-term treatment outcome in HCV following 24 day PEG-IFN alpha-2b therapy using population pharmacokinetic-pharmacodynamic mixture modeling and classification analysis.

Vinogradova SV, Zhudenkov KV, Benson N, Van Der Graaf PH, Demin OV, Karelina TA.

J Theor Biol. 2015 Oct 7;382:91-8. doi: 10.1016/j.jtbi.2015.06.041. Epub 2015 Jul 8.

PMID:
26163367
4.

Comparison of asymptotic confidence sets for regression in small samples.

Kolobkov D, Demin O, Metelkin E.

J Biopharm Stat. 2016;26(4):742-57. doi: 10.1080/10543406.2015.1052818. Epub 2015 Jun 22.

PMID:
26099035
5.

Analysis of the efficacy of SGLT2 inhibitors using semi-mechanistic model.

Demin O Jr, Yakovleva T, Kolobkov D, Demin O.

Front Pharmacol. 2014 Oct 13;5:218. doi: 10.3389/fphar.2014.00218. eCollection 2014.

6.

Systems pharmacology of the nerve growth factor pathway: use of a systems biology model for the identification of key drug targets using sensitivity analysis and the integration of physiology and pharmacology.

Benson N, Matsuura T, Smirnov S, Demin O, Jones HM, Dua P, van der Graaf PH.

Interface Focus. 2013 Apr 6;3(2):20120071. doi: 10.1098/rsfs.2012.0071.

7.

Modeling of celiac disease immune response and the therapeutic effect of potential drugs.

Demin OO, Smirnov SV, Sokolov VV, Cucurull-Sanchez L, Pichardo-Almarza C, Flores MV, Benson N, Demin OV.

BMC Syst Biol. 2013 Jul 5;7:56. doi: 10.1186/1752-0509-7-56.

8.

Regulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach.

Karelina TA, Zhudenkov KV, Demin OO, Svetlichny DV, Agoram B, Fairman D, Demin OV.

BMC Syst Biol. 2012 Nov 12;6:141. doi: 10.1186/1752-0509-6-141.

9.

Kinetic modelling of central carbon metabolism in Escherichia coli.

Peskov K, Mogilevskaya E, Demin O.

FEBS J. 2012 Sep;279(18):3374-85. doi: 10.1111/j.1742-4658.2012.08719.x.

10.

Integration not isolation: arguing the case for quantitative and systems pharmacology in drug discovery and development.

Agoram BM, Demin O.

Drug Discov Today. 2011 Dec;16(23-24):1031-6. doi: 10.1016/j.drudis.2011.10.001. Epub 2011 Oct 13. Review.

PMID:
22020181
11.

DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results.

Gizzatkulov NM, Goryanin II, Metelkin EA, Mogilevskaya EA, Peskov KV, Demin OV.

BMC Syst Biol. 2010 Aug 10;4:109. doi: 10.1186/1752-0509-4-109.

12.

In Silico Screening of Nonsteroidal Anti-Inflammatory Drugs and Their Combined Action on Prostaglandin H Synthase-1.

Goltsov A, Lebedeva G, Humphery-Smith I, Goltsov G, Demin O, Goryanin I.

Pharmaceuticals (Basel). 2010 Jul 2;3(7):2059-2081.

13.

Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria.

Metelkin E, Demin O, Kovács Z, Chinopoulos C.

FEBS J. 2009 Dec;276(23):6942-55. doi: 10.1111/j.1742-4658.2009.07394.x. Epub 2009 Oct 26.

14.

Kinetic modeling as a tool to integrate multilevel dynamic experimental data.

Mogilevskaya E, Bagrova N, Plyusnina T, Gizzatkulov N, Metelkin E, Goryacheva E, Smirnov S, Kosinsky Y, Dorodnov A, Peskov K, Karelina T, Goryanin I, Demin O.

Methods Mol Biol. 2009;563:197-218. doi: 10.1007/978-1-60761-175-2_11.

PMID:
19597787
15.

Kinetic modelling of NSAID action on COX-1: focus on in vitro/in vivo aspects and drug combinations.

Goltsov A, Maryashkin A, Swat M, Kosinsky Y, Humphery-Smith I, Demin O, Goryanin I, Lebedeva G.

Eur J Pharm Sci. 2009 Jan 31;36(1):122-36. doi: 10.1016/j.ejps.2008.10.015. Epub 2008 Nov 5.

PMID:
19028575
16.

Kinetic modeling of ace operon genetic regulation in Escherichia coli.

Peskov K, Goryanin I, Prank K, Tobin F, Demin O.

J Bioinform Comput Biol. 2008 Oct;6(5):933-59.

PMID:
18942160
17.

Kinetic model of phosphofructokinase-1 from Escherichia coli.

Peskov K, Goryanin I, Demin O.

J Bioinform Comput Biol. 2008 Aug;6(4):843-67.

PMID:
18763746
18.

The Edinburgh human metabolic network reconstruction and its functional analysis.

Ma H, Sorokin A, Mazein A, Selkov A, Selkov E, Demin O, Goryanin I.

Mol Syst Biol. 2007;3:135. Epub 2007 Sep 18.

19.

Kinetic model of mitochondrial Krebs cycle: unraveling the mechanism of salicylate hepatotoxic effects.

Mogilevskaya E, Demin O, Goryanin I.

J Biol Phys. 2006 Oct;32(3-4):245-71. doi: 10.1007/s10867-006-9015-y. Epub 2006 Oct 26.

20.

Cellular kinetic modeling of the microbial metabolism.

Goryanin II, Lebedeva GV, Mogilevskaya EA, Metelkin EA, Demin OV.

Methods Biochem Anal. 2006;49:437-88. Review. No abstract available.

PMID:
16929691

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