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Items: 1 to 20 of 65

1.

Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation.

Kumar D, Lee B, Puan KJ, Lee W, Luis BS, Yusof N, Andiappan AK, Del Rosario R, Poschmann J, Kumar P, DeLibero G, Singhal A, Prabhakar S, De Yun W, Poidinger M, Rötzschke O.

Sci Rep. 2019 Oct 23;9(1):15245. doi: 10.1038/s41598-019-51592-0.

2.

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications.

Tan KS, Andiappan AK, Lee B, Yan Y, Liu J, Tang SA, Lum J, He TT, Ong YK, Thong M, Lim HF, Choi HW, Rotzschke O, Chow VT, Wang Y.

Cells. 2019 Aug 27;8(9). pii: E986. doi: 10.3390/cells8090986.

3.

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.

Porcu E, Rüeger S, Lepik K; eQTLGen Consortium; BIOS Consortium, Santoni FA, Reymond A, Kutalik Z.

Nat Commun. 2019 Jul 24;10(1):3300. doi: 10.1038/s41467-019-10936-0.

4.

A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium.

Luukkainen A, Puan KJ, Yusof N, Lee B, Tan KS, Liu J, Yan Y, Toppila-Salmi S, Renkonen R, Chow VT, Rotzschke O, Wang Y.

Front Immunol. 2018 Nov 8;9:2514. doi: 10.3389/fimmu.2018.02514. eCollection 2018.

5.

Biomarker Signatures Predicting 10-Year All-Cause and Disease-Specific Mortality.

Lu Y, Monaco G, Camous X, Andiappan AK, Rotzschke O, Ng TP, Larbi A.

J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):469-479. doi: 10.1093/gerona/gly138.

PMID:
30084875
6.

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.

Xue A, Wu Y, Zhu Z, Zhang F, Kemper KE, Zheng Z, Yengo L, Lloyd-Jones LR, Sidorenko J, Wu Y; eQTLGen Consortium, McRae AF, Visscher PM, Zeng J, Yang J.

Nat Commun. 2018 Jul 27;9(1):2941. doi: 10.1038/s41467-018-04951-w.

7.

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood.

Qi T, Wu Y, Zeng J, Zhang F, Xue A, Jiang L, Zhu Z, Kemper K, Yengo L, Zheng Z; eQTLGen Consortium, Marioni RE, Montgomery GW, Deary IJ, Wray NR, Visscher PM, McRae AF, Yang J.

Nat Commun. 2018 Jun 11;9(1):2282. doi: 10.1038/s41467-018-04558-1.

8.

C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis.

Lepik K, Annilo T, Kukuškina V; eQTLGen Consortium, Kisand K, Kutalik Z, Peterson P, Peterson H.

PLoS Comput Biol. 2017 Sep 18;13(9):e1005766. doi: 10.1371/journal.pcbi.1005766. eCollection 2017 Sep.

9.

Analysis of T Cell Subsets in Adult Primary/Idiopathic Minimal Change Disease: A Pilot Study.

Salcido-Ochoa F, Hue SS, Haase D, Choo JCJ, Yusof N, Li RL, Allen JC Jr, Iqbal J, Loh AHL, Rotzschke O.

Int J Nephrol. 2017;2017:3095425. doi: 10.1155/2017/3095425. Epub 2017 Aug 15.

10.

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease.

Obeidat M, Nie Y, Chen V, Shannon CP, Andiappan AK, Lee B, Rotzschke O, Castaldi PJ, Hersh CP, Fishbane N, Ng RT, McManus B, Miller BE, Rennard S, Paré PD, Sin DD.

Respir Res. 2017 Apr 24;18(1):72. doi: 10.1186/s12931-017-0558-1.

11.

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.

Kumar D, Puan KJ, Andiappan AK, Lee B, Westerlaken GH, Haase D, Melchiotti R, Li Z, Yusof N, Lum J, Koh G, Foo S, Yeong J, Alves AC, Pekkanen J, Sun LD, Irwanto A, Fairfax BP, Naranbhai V, Common JE, Tang M, Chuang CK, Jarvelin MR, Knight JC, Zhang X, Chew FT, Prabhakar S, Jianjun L, Wang Y, Zolezzi F, Poidinger M, Lane EB, Meyaard L, Rötzschke O.

Genome Med. 2017 Feb 20;9(1):18. doi: 10.1186/s13073-017-0404-6.

12.

Fingolimod treatment abrogates chikungunya virus-induced arthralgia.

Teo TH, Chan YH, Lee WW, Lum FM, Amrun SN, Her Z, Rajarethinam R, Merits A, Rötzschke O, Rénia L, Ng LF.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaal1333. doi: 10.1126/scitranslmed.aal1333.

PMID:
28148838
13.

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.

Hadadi E, Zhang B, Baidžajevas K, Yusof N, Puan KJ, Ong SM, Yeap WH, Rotzschke O, Kiss-Toth E, Wilson H, Wong SC.

Sci Rep. 2016 Dec 15;6:39035. doi: 10.1038/srep39035.

14.

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.

Lee WW, Teo TH, Lum FM, Andiappan AK, Amrun SN, Rénia L, Rötzschke O, Ng LF.

Sci Rep. 2016 Nov 25;6:37603. doi: 10.1038/srep37603.

15.

Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.

Penny HL, Sieow JL, Adriani G, Yeap WH, See Chi Ee P, San Luis B, Lee B, Lee T, Mak SY, Ho YS, Lam KP, Ong CK, Huang RY, Ginhoux F, Rotzschke O, Kamm RD, Wong SC.

Oncoimmunology. 2016 Jun 21;5(8):e1191731. doi: 10.1080/2162402X.2016.1191731. eCollection 2016 Aug.

16.

Immune Modulation and Prevention of Autoimmune Disease by Repeated Sequences from Parasites Linked to Self Antigens.

Puentes F, Dickhaut K, Hofstätter M, Pfeil J, Lauer U, Hamann A, Hoffmann U, Falk K, Rötzschke O.

J Neuroimmune Pharmacol. 2016 Dec;11(4):749-762. Epub 2016 Aug 12.

PMID:
27518777
17.

Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.

Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J.

Sci Rep. 2016 Aug 10;6:31429. doi: 10.1038/srep31429.

18.

Neuropeptide Y associated with asthma in young adults.

Lu Y, Andiappan AK, Lee B, Ho R, Lim TK, Kuan WS, Goh DY, Mahadevan M, Sim TB, Wang Y, Van Bever HP, Rotzschke O, Larbi A, Ng TP.

Neuropeptides. 2016 Oct;59:117-121. doi: 10.1016/j.npep.2016.07.003. Epub 2016 Jul 20.

PMID:
27469060
19.

Vδ2+ and α/ß T cells show divergent trajectories during human aging.

Tan CT, Wistuba-Hamprecht K, Xu W, Nyunt MS, Vasudev A, Lee BT, Pawelec G, Puan KJ, Rotzschke O, Ng TP, Larbi A.

Oncotarget. 2016 Jul 19;7(29):44906-44918. doi: 10.18632/oncotarget.10096.

20.

Systematic characterization of basophil anergy.

Puan KJ, Andiappan AK, Lee B, Kumar D, Lai TS, Yeo G, Bercin D, Starke M, Haase D, Lum J, Chew FT, Connolly J, Wong SC, Zolezzi F, Poidinger M, Wang Y, Rötzschke O.

Allergy. 2017 Mar;72(3):373-384. doi: 10.1111/all.12952. Epub 2016 Aug 8.

PMID:
27271846

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