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Items: 8

1.

Bradykinin receptor-1 activation induces inflammation and increases the permeability of human brain microvascular endothelial cells.

Mugisho OO, Nicholson LF, Graham ES, O'Carroll SJ.

Cell Biol Int. 2019 Sep 9. doi: 10.1002/cbin.11232. [Epub ahead of print]

PMID:
31498530
2.

Connexin43 hemichannel block protects against retinal pigment epithelial cell barrier breakdown.

Kuo C, Green CR, Rupenthal ID, Mugisho OO.

Acta Diabetol. 2019 Apr 27. doi: 10.1007/s00592-019-01352-3. [Epub ahead of print]

PMID:
31030263
3.

Depot formulations to sustain periocular drug delivery to the posterior eye segment.

Agban Y, Thakur SS, Mugisho OO, Rupenthal ID.

Drug Discov Today. 2019 Aug;24(8):1458-1469. doi: 10.1016/j.drudis.2019.03.023. Epub 2019 Mar 28. Review.

PMID:
30930148
4.

Connexin43 hemichannels: A potential drug target for the treatment of diabetic retinopathy.

Mugisho OO, Green CR, Zhang J, Acosta ML, Rupenthal ID.

Drug Discov Today. 2019 Aug;24(8):1627-1636. doi: 10.1016/j.drudis.2019.01.011. Epub 2019 Jan 25. Review.

PMID:
30690195
5.

Connexin43 hemichannel block protects against the development of diabetic retinopathy signs in a mouse model of the disease.

Mugisho OO, Green CR, Squirrell DM, Bould S, Danesh-Meyer HV, Zhang J, Acosta ML, Rupenthal ID.

J Mol Med (Berl). 2019 Feb;97(2):215-229. doi: 10.1007/s00109-018-1727-5. Epub 2018 Dec 8.

PMID:
30535867
6.

Intravitreal pro-inflammatory cytokines in non-obese diabetic mice: Modelling signs of diabetic retinopathy.

Mugisho OO, Rupenthal ID, Squirrell DM, Bould SJ, Danesh-Meyer HV, Zhang J, Green CR, Acosta ML.

PLoS One. 2018 Aug 22;13(8):e0202156. doi: 10.1371/journal.pone.0202156. eCollection 2018.

7.

Immunohistochemical Characterization of Connexin43 Expression in a Mouse Model of Diabetic Retinopathy and in Human Donor Retinas.

Mugisho OO, Green CR, Zhang J, Binz N, Acosta ML, Rakoczy E, Rupenthal ID.

Int J Mol Sci. 2017 Nov 29;18(12). pii: E2567. doi: 10.3390/ijms18122567.

8.

The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release.

Mugisho OO, Green CR, Kho DT, Zhang J, Graham ES, Acosta ML, Rupenthal ID.

Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):385-393. doi: 10.1016/j.bbagen.2017.11.015. Epub 2017 Nov 21.

PMID:
29158134

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