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Items: 16

1.

Predictive power of the Triticum root elongation test for the assessment of novel anti‑proliferative therapies.

Olaru OT, Zanfirescu A, Nitulescu GM, Nitulescu G, Dinu-Pirvu CE, Anuta V, Tsatsakis A, Spandidos DA, Margina D, Seremet OC.

Int J Mol Med. 2019 Jul;44(1):16-24. doi: 10.3892/ijmm.2019.4192. Epub 2019 May 10.

2.

In Vitro Anti-proliferative Activity and Mechanism of Action of Anemone nemorosa.

Swanepoel B, Venables L, Olaru OT, Nitulescu GM, van de Venter M.

Int J Mol Sci. 2019 Mar 11;20(5). pii: E1217. doi: 10.3390/ijms20051217.

3.

The Akt pathway in oncology therapy and beyond (Review).

Nitulescu GM, Van De Venter M, Nitulescu G, Ungurianu A, Juzenas P, Peng Q, Olaru OT, Grădinaru D, Tsatsakis A, Tsoukalas D, Spandidos DA, Margina D.

Int J Oncol. 2018 Dec;53(6):2319-2331. doi: 10.3892/ijo.2018.4597. Epub 2018 Oct 16. Review.

4.

Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models.

Seremet OC, Olaru OT, Gutu CM, Nitulescu GM, Ilie M, Negres S, Zbarcea CE, Purdel CN, Spandidos DA, Tsatsakis AM, Coleman MD, Margina DM.

Mol Med Rep. 2018 Jun;17(6):7757-7763. doi: 10.3892/mmr.2018.8795. Epub 2018 Mar 26.

5.

Molecular Docking and Screening Studies of New Natural Sortase A Inhibitors.

Nitulescu G, Nicorescu IM, Olaru OT, Ungurianu A, Mihai DP, Zanfirescu A, Nitulescu GM, Margina D.

Int J Mol Sci. 2017 Oct 23;18(10). pii: E2217. doi: 10.3390/ijms18102217.

6.

Synthesis, Characterization, Antimicrobial and Antiproliferative Activity Evaluation of Cu(II), Co(II), Zn(II), Ni(II) and Pt(II) Complexes with Isoniazid-Derived Compound.

Pahonțu E, Ilieș DC, Shova S, Oprean C, Păunescu V, Olaru OT, Rădulescu FȘ, Gulea A, Roșu T, Drăgănescu D.

Molecules. 2017 Apr 19;22(4). pii: E650. doi: 10.3390/molecules22040650.

7.

Oral toxicity study of certain plant extracts containing pyrrolizidine alkaloids.

Şeremet OC, Bărbuceanu F, Ionică FE, Margină DM, GuŢu CM, Olaru OT, Ilie M, Gonciar V, Negreş S, ChiriŢă C.

Rom J Morphol Embryol. 2016;57(3):1017-1023.

8.

Structural Analysis of Sortase A Inhibitors.

Nitulescu G, Zanfirescu A, Olaru OT, Nicorescu IM, Nitulescu GM, Margina D.

Molecules. 2016 Nov 22;21(11). pii: E1591.

9.

Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review).

Nitulescu GM, Margina D, Juzenas P, Peng Q, Olaru OT, Saloustros E, Fenga C, Spandidos DΑ, Libra M, Tsatsakis AM.

Int J Oncol. 2016 Mar;48(3):869-85. doi: 10.3892/ijo.2015.3306. Epub 2015 Dec 24. Review.

10.

Comparative evaluation of short-term toxicity of inorganic arsenic compounds on Artemia salina.

GuŢu CM, Olaru OT, Purdel NC, Ilie M, NeamŢu MC, Dănciulescu Miulescu R, Avramescu ET, Margină DM.

Rom J Morphol Embryol. 2015;56(3):1091-6.

11.

Assessment of the potential health benefits of certain total extracts from Vitis vinifera, Aesculus hyppocastanum and Curcuma longa.

Margină D, Olaru OT, Ilie M, Grădinaru D, GuȚu C, Voicu S, Dinischiotu A, Spandidos DA, Tsatsakis AM.

Exp Ther Med. 2015 Nov;10(5):1681-1688. Epub 2015 Sep 2.

12.

Anticancer potential of selected Fallopia Adans species.

Olaru OT, Venables L, VAN DE Venter M, Nitulescu GM, Margina D, Spandidos DA, Tsatsakis AM.

Oncol Lett. 2015 Sep;10(3):1323-1332. Epub 2015 Jul 2.

13.

Ethnomedicinal, Phytochemical and Pharmacological Profile of Anthriscus sylvestris as an Alternative Source for Anticancer Lignans.

Olaru OT, Niţulescu GM, Orțan A, Dinu-Pîrvu CE.

Molecules. 2015 Aug 17;20(8):15003-22. doi: 10.3390/molecules200815003. Review.

14.

Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines.

Nitulescu GM, Draghici C, Olaru OT, Matei L, Ioana A, Dragu LD, Bleotu C.

Bioorg Med Chem. 2015 Sep 1;23(17):5799-808. doi: 10.1016/j.bmc.2015.07.010. Epub 2015 Jul 11.

PMID:
26193760
15.

Biopharmaceutical profiling of new antitumor pyrazole derivatives.

Anuta V, Nitulescu GM, Dinu-Pîrvu CE, Olaru OT.

Molecules. 2014 Oct 13;19(10):16381-401. doi: 10.3390/molecules191016381.

16.

New potential antitumor pyrazole derivatives: synthesis and cytotoxic evaluation.

Nitulescu GM, Draghici C, Olaru OT.

Int J Mol Sci. 2013 Nov 4;14(11):21805-18. doi: 10.3390/ijms141121805.

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