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Items: 1 to 20 of 94


FZD10 Carried by Exosomes Sustains Cancer Cell Proliferation.

Scavo MP, Depalo N, Rizzi F, Ingrosso C, Fanizza E, Chieti A, Messa C, Denora N, Laquintana V, Striccoli M, Curri ML, Giannelli G.

Cells. 2019 Jul 25;8(8). pii: E777. doi: 10.3390/cells8080777.


Frizzled-10 Extracellular Vesicles Plasma Concentration Is Associated with Tumoral Progression in Patients with Colorectal and Gastric Cancer.

Principia SM, Antonio C, Nicoletta D, Elisabetta F, Bianco MG, Nunzio D, Valentino L, Maria Lucia C, Dionigi L, Claudio L, Alba P, Gianluigi G.

J Oncol. 2019 Jun 2;2019:2715968. doi: 10.1155/2019/2715968. eCollection 2019.


Green Fluorescent Terbium (III) Complex Doped Silica Nanoparticles.

Fanizza E, Depalo N, Fedorenko S, Iacobazzi RM, Mukhametshina A, Zairov R, Salatino A, Vischio F, Panniello A, Laquintana V, Curri ML, Mustafina A, Denora N, Striccoli M.

Int J Mol Sci. 2019 Jun 27;20(13). pii: E3139. doi: 10.3390/ijms20133139.


Some Preformulation Studies of Pyruvic Acid and Other α-Keto Carboxylic Acids in Aqueous Solution: Pharmaceutical Formulation Implications for These Peroxide Scavengers.

Lopalco A, Deeken R, Douglas J, Denora N, Stella VJ.

J Pharm Sci. 2019 Jun 1. pii: S0022-3549(19)30363-6. doi: 10.1016/j.xphs.2019.05.030. [Epub ahead of print]


1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity.

Franchini S, Sorbi C, Linciano P, Carnevale G, Tait A, Ronsisvalle S, Buccioni M, Del Bello F, Cilia A, Pirona L, Denora N, Iacobazzi RM, Brasili L.

Eur J Med Chem. 2019 Aug 15;176:310-325. doi: 10.1016/j.ejmech.2019.05.024. Epub 2019 May 11.


Unveiling the Efficacy, Safety, and Tolerability of Anti-Interleukin-1 Treatment in Monogenic and Multifactorial Autoinflammatory Diseases.

Bettiol A, Lopalco G, Emmi G, Cantarini L, Urban ML, Vitale A, Denora N, Lopalco A, Cutrignelli A, Lopedota A, Venerito V, Fornaro M, Vannacci A, Rigante D, Cimaz R, Iannone F.

Int J Mol Sci. 2019 Apr 17;20(8). pii: E1898. doi: 10.3390/ijms20081898. Review.


FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice.

Marcuzzo S, Isaia D, Bonanno S, Malacarne C, Cavalcante P, Zacheo A, Laquintana V, Denora N, Sanavio B, Salvati E, Andreozzi P, Stellacci F, Krol S, Mellado-López M, Mantegazza R, Moreno-Manzano V, Bernasconi P.

Cells. 2019 Mar 23;8(3). pii: E279. doi: 10.3390/cells8030279.


Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.

Oukoloff K, Coquelle N, Bartolini M, Naldi M, Le Guevel R, Bach S, Josselin B, Ruchaud S, Catto M, Pisani L, Denora N, Iacobazzi RM, Silman I, Sussman JL, Buron F, Colletier JP, Jean L, Routier S, Renard PY.

Eur J Med Chem. 2019 Apr 15;168:58-77. doi: 10.1016/j.ejmech.2018.12.063. Epub 2019 Feb 13.


Dasatinib/HP-β-CD Inclusion Complex Based Aqueous Formulation as a Promising Tool for the Treatment of Paediatric Neuromuscular Disorders.

Cutrignelli A, Sanarica F, Lopalco A, Lopedota A, Laquintana V, Franco M, Boccanegra B, Mantuano P, De Luca A, Denora N.

Int J Mol Sci. 2019 Jan 30;20(3). pii: E591. doi: 10.3390/ijms20030591.


Pharmaceutical preformulation studies and paediatric oral formulations of sodium dichloroacetate.

Lopalco A, Curci A, Lopedota A, Cutrignelli A, Laquintana V, Franco M, Denora N.

Eur J Pharm Sci. 2019 Jan 15;127:339-350. doi: 10.1016/j.ejps.2018.11.013. Epub 2018 Nov 15.


Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors.

Pisani L, Iacobazzi RM, Catto M, Rullo M, Farina R, Denora N, Cellamare S, Altomare CD.

Eur J Med Chem. 2019 Jan 1;161:292-309. doi: 10.1016/j.ejmech.2018.10.016. Epub 2018 Oct 10.


S-preactivated thiolated glycol chitosan useful to combine mucoadhesion and drug delivery.

Perrone M, Lopalco A, Lopedota A, Cutrignelli A, Laquintana V, Franco M, Bernkop-Schnürch A, Denora N.

Eur J Pharm Biopharm. 2018 Nov;132:103-111. doi: 10.1016/j.ejpb.2018.09.015. Epub 2018 Sep 22.


Preclinical comparison study between [18F]fluoromethyl-PBR28 and its deuterated analog in a rat model of neuroinflammation.

Moon BS, Jung JH, Park HS, Contino M, Denora N, Lee BC, Kim SE.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2925-2929. doi: 10.1016/j.bmcl.2018.07.011. Epub 2018 Jul 5.


Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain.

Franchini S, Bencheva LI, Battisti UM, Tait A, Sorbi C, Fossa P, Cichero E, Ronsisvalle S, Aricò G, Denora N, Iacobazzi RM, Cilia A, Pirona L, Brasili L.

Future Med Chem. 2018 Sep 1;10(18):2137-2154. doi: 10.4155/fmc-2018-0107. Epub 2018 Jul 25.


Nanoformulations for Drug Delivery: Safety, Toxicity, and Efficacy.

Lopalco A, Denora N.

Methods Mol Biol. 2018;1800:347-365. doi: 10.1007/978-1-4939-7899-1_17.


Contact allergy to electrocardiogram electrodes caused by acrylic acid without sensitivity to methacrylates and ethyl cyanoacrylate.

Foti C, Lopalco A, Stingeni L, Hansel K, Lopedota A, Denora N, Romita P.

Contact Dermatitis. 2018 May 11. doi: 10.1111/cod.13015. [Epub ahead of print] No abstract available.


Delivery of Proapoptotic Agents in Glioma Cell Lines by TSPO Ligand-Dextran Nanogels.

Lopalco A, Cutrignelli A, Denora N, Perrone M, Iacobazzi RM, Fanizza E, Lopedota A, Depalo N, de Candia M, Franco M, Laquintana V.

Int J Mol Sci. 2018 Apr 11;19(4). pii: E1155. doi: 10.3390/ijms19041155.


Automated identification of structurally heterogeneous and patentable antiproliferative hits as potential tubulin inhibitors.

Mangiatordi GF, Trisciuzzi D, Iacobazzi R, Denora N, Pisani L, Catto M, Leonetti F, Alberga D, Nicolotti O.

Chem Biol Drug Des. 2018 Jul;92(1):1161-1170. doi: 10.1111/cbdd.13200. Epub 2018 Apr 27.


Transferrin Functionalized Liposomes Loading Dopamine HCl: Development and Permeability Studies across an In Vitro Model of Human Blood-Brain Barrier.

Lopalco A, Cutrignelli A, Denora N, Lopedota A, Franco M, Laquintana V.

Nanomaterials (Basel). 2018 Mar 20;8(3). pii: E178. doi: 10.3390/nano8030178.


One pot environmental friendly synthesis of gold nanoparticles using Punica Granatum Juice: A novel antioxidant agent for future dermatological and cosmetic applications.

Gubitosa J, Rizzi V, Lopedota A, Fini P, Laurenzana A, Fibbi G, Fanelli F, Petrella A, Laquintana V, Denora N, Comparelli R, Cosma P.

J Colloid Interface Sci. 2018 Jul 1;521:50-61. doi: 10.1016/j.jcis.2018.02.069. Epub 2018 Mar 9.


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