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Items: 1 to 20 of 47

1.

Amino Acids in the Development of Prodrugs.

Vale N, Ferreira A, Matos J, Fresco P, Gouveia MJ.

Molecules. 2018 Sep 11;23(9). pii: E2318. doi: 10.3390/molecules23092318. Review.

2.

Microglia P2Y13 Receptors Prevent Astrocyte Proliferation Mediated by P2Y1 Receptors.

Quintas C, Vale N, Gonçalves J, Queiroz G.

Front Pharmacol. 2018 May 3;9:418. doi: 10.3389/fphar.2018.00418. eCollection 2018.

3.

A novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates.

Almeida JR, Mendes B, Lancellotti M, Marangoni S, Vale N, Passos Ó, Ramos MJ, Fernandes PA, Gomes P, Da Silva SL.

Eur J Med Chem. 2018 Apr 10;149:248-256. doi: 10.1016/j.ejmech.2018.02.055. Epub 2018 Feb 21.

PMID:
29501945
4.

Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules.

Gouveia MJ, Brindley PJ, Gärtner F, Costa JMCD, Vale N.

Pharmaceuticals (Basel). 2018 Feb 5;11(1). pii: E15. doi: 10.3390/ph11010015. Review.

5.

Synergistic and antibiofilm properties of ocellatin peptides against multidrug-resistant Pseudomonas aeruginosa.

Bessa LJ, Eaton P, Dematei A, Plácido A, Vale N, Gomes P, Delerue-Matos C, Sa Leite JR, Gameiro P.

Future Microbiol. 2018 Feb;13:151-163. doi: 10.2217/fmb-2017-0175. Epub 2018 Jan 8.

PMID:
29308671
6.

Unravelling a Mechanism of Action for a Cecropin A-Melittin Hybrid Antimicrobial Peptide: The Induced Formation of Multilamellar Lipid Stacks.

Silva T, Claro B, Silva BFB, Vale N, Gomes P, Gomes MS, Funari SS, Teixeira J, Uhríková D, Bastos M.

Langmuir. 2018 Feb 6;34(5):2158-2170. doi: 10.1021/acs.langmuir.7b03639. Epub 2018 Jan 22.

PMID:
29304549
7.

Structure and function of a novel antioxidant peptide from the skin of tropical frogs.

Barbosa EA, Oliveira A, Plácido A, Socodato R, Portugal CC, Mafud AC, Ombredane AS, Moreira DC, Vale N, Bessa LJ, Joanitti GA, Alves C, Gomes P, Delerue-Matos C, Mascarenhas YP, Marani MM, Relvas JB, Pintado M, Leite JRSA.

Free Radic Biol Med. 2018 Feb 1;115:68-79. doi: 10.1016/j.freeradbiomed.2017.11.001. Epub 2017 Nov 21.

PMID:
29162516
8.

Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model.

Gouveia MJ, Pakharukova MY, Laha T, Sripa B, Maksimova GA, Rinaldi G, Brindley PJ, Mordvinov VA, Amaro T, Santos LL, Costa JMCD, Vale N.

Carcinogenesis. 2017 Sep 1;38(9):929-937. doi: 10.1093/carcin/bgx042.

9.

Lactoferricin Peptides Increase Macrophages' Capacity To Kill Mycobacterium avium.

Silva T, Moreira AC, Nazmi K, Moniz T, Vale N, Rangel M, Gomes P, Bolscher JGM, Rodrigues PN, Bastos M, Gomes MS.

mSphere. 2017 Aug 30;2(4). pii: e00301-17. doi: 10.1128/mSphere.00301-17. eCollection 2017 Jul-Aug.

10.

Structure-function studies of BPP-BrachyNH2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme.

Arcanjo DDR, Vasconcelos AG, Nascimento LA, Mafud AC, Plácido A, Alves MMM, Delerue-Matos C, Bemquerer MP, Vale N, Gomes P, Oliveira EB, Lima FCA, Mascarenhas YP, Carvalho FAA, Simonsen U, Ramos RM, Leite JRSA.

Eur J Med Chem. 2017 Oct 20;139:401-411. doi: 10.1016/j.ejmech.2017.08.019. Epub 2017 Aug 7.

PMID:
28810191
11.

In vitro studies on the inhibition of colon cancer by amino acid derivatives of bromothiazole.

Vale N, Correia-Branco A, Patrício B, Duarte D, Martel F.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3507-3510. doi: 10.1016/j.bmcl.2017.05.073. Epub 2017 May 26.

PMID:
28601526
12.

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins.

Dias SA, Freire JM, Pérez-Peinado C, Domingues MM, Gaspar D, Vale N, Gomes P, Andreu D, Henriques ST, Castanho MARB, Veiga AS.

Front Microbiol. 2017 May 4;8:775. doi: 10.3389/fmicb.2017.00775. eCollection 2017.

13.

Gemcitabine anti-proliferative activity significantly enhanced upon conjugation with cell-penetrating peptides.

Vale N, Ferreira A, Fernandes I, Alves C, Araújo MJ, Mateus N, Gomes P.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2898-2901. doi: 10.1016/j.bmcl.2017.04.086. Epub 2017 Apr 28.

PMID:
28495087
14.

Tethering antimicrobial peptides onto chitosan: Optimization of azide-alkyne "click" reaction conditions.

Barbosa M, Vale N, Costa FM, Martins MC, Gomes P.

Carbohydr Polym. 2017 Jun 1;165:384-393. doi: 10.1016/j.carbpol.2017.02.050. Epub 2017 Feb 17.

PMID:
28363563
15.

The role of estradiol metabolism in urogenital schistosomiasis-induced bladder cancer.

Vale N, Gouveia MJ, Rinaldi G, Santos J, Santos LL, Brindley PJ, da Costa JM.

Tumour Biol. 2017 Mar;39(3):1010428317692247. doi: 10.1177/1010428317692247. Review.

PMID:
28345469
16.

Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.

Vale N, Gouveia MJ, Rinaldi G, Brindley PJ, Gärtner F, Correia da Costa JM.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02582-16. doi: 10.1128/AAC.02582-16. Print 2017 May. Review.

17.

Interaction between Wine Phenolic Acids and Salivary Proteins by Saturation-Transfer Difference Nuclear Magnetic Resonance Spectroscopy (STD-NMR) and Molecular Dynamics Simulations.

Ferrer-Gallego R, Hernández-Hierro JM, Brás NF, Vale N, Gomes P, Mateus N, de Freitas V, Heredia FJ, Escribano-Bailón MT.

J Agric Food Chem. 2017 Aug 9;65(31):6434-6441. doi: 10.1021/acs.jafc.6b05414. Epub 2017 Mar 10.

PMID:
28251854
18.

Preparation and biological evaluation of ethionamide-mesoporous silicon nanoparticles against Mycobacterium tuberculosis.

Vale N, Correia A, Silva S, Figueiredo P, Mäkilä E, Salonen J, Hirvonen J, Pedrosa J, Santos HA, Fraga A.

Bioorg Med Chem Lett. 2017 Feb 1;27(3):403-405. doi: 10.1016/j.bmcl.2016.12.060. Epub 2016 Dec 26.

PMID:
28057421
19.

Ocellatin-PT antimicrobial peptides: High-resolution microscopy studies in antileishmania models and interactions with mimetic membrane systems.

Oliveira M, Gomes-Alves AG, Sousa C, Mirta Marani M, Plácido A, Vale N, Delerue-Matos C, Gameiro P, Kückelhaus SA, Tomas AM, S A Leite JR, Eaton P.

Biopolymers. 2016 Dec;105(12):873-86. doi: 10.1002/bip.22925.

PMID:
27463422
20.

Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer.

Gouveia MJ, Santos J, Brindley PJ, Rinaldi G, Lopes C, Santos LL, da Costa JM, Vale N.

Cancer Lett. 2015 Apr 10;359(2):226-32. doi: 10.1016/j.canlet.2015.01.018. Epub 2015 Jan 20.

PMID:
25615421

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