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Items: 1 to 20 of 26


PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation.

Yoneda M, Suzuki H, Hatano N, Nakano S, Muraki Y, Miyazawa K, Goto S, Muraki K.

Int J Mol Sci. 2019 Oct 8;20(19). pii: E4960. doi: 10.3390/ijms20194960.


Castration Induces Down-Regulation of A-Type K+ Channel in Rat Vas Deferens Smooth Muscle.

Ohya S, Ito K, Hatano N, Ohno A, Muraki K, Imaizumi Y.

Int J Mol Sci. 2019 Aug 21;20(17). pii: E4073. doi: 10.3390/ijms20174073.


PIEZO1 Channel Is a Potential Regulator of Synovial Sarcoma Cell-Viability.

Suzuki T, Muraki Y, Hatano N, Suzuki H, Muraki K.

Int J Mol Sci. 2018 May 14;19(5). pii: E1452. doi: 10.3390/ijms19051452.


ATP increases [Ca2+ ]i and activates a Ca2+ -dependent Cl- current in rat ventricular fibroblasts.

Hatano N, Ohya S, Imaizumi Y, Clark RB, Belke D, Giles WR.

Exp Physiol. 2018 May 1;103(5):666-682. doi: 10.1113/EP086822. Epub 2018 Apr 15.


Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells.

Muraki K, Ohnishi K, Takezawa A, Suzuki H, Hatano N, Muraki Y, Hamzah N, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Beech DJ.

Sci Rep. 2017 Dec 5;7(1):16988. doi: 10.1038/s41598-017-17303-3.


An environmental pollutant, 9,10-phenanthrenequinone, activates human TRPA1 via critical cysteines 621 and 665.

Muraki K, Sekine T, Ando Y, Suzuki H, Hatano N, Hirata T, Muraki Y.

Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.342.


Diclofenac, a nonsteroidal anti-inflammatory drug, is an antagonist of human TRPM3 isoforms.

Suzuki H, Sasaki E, Nakagawa A, Muraki Y, Hatano N, Muraki K.

Pharmacol Res Perspect. 2016 Apr 7;4(3):e00232. doi: 10.1002/prp2.232. eCollection 2016 Jun.


Downregulation of the Ca(2+)-activated K(+) channel KC a3.1 by histone deacetylase inhibition in human breast cancer cells.

Ohya S, Kanatsuka S, Hatano N, Kito H, Matsui A, Fujimoto M, Matsuba S, Niwa S, Zhan P, Suzuki T, Muraki K.

Pharmacol Res Perspect. 2016 Mar 17;4(2):e00228. doi: 10.1002/prp2.228. eCollection 2016 Apr.


Recent advances in therapeutic strategies that focus on the regulation of ion channel expression.

Ohya S, Kito H, Hatano N, Muraki K.

Pharmacol Ther. 2016 Apr;160:11-43. doi: 10.1016/j.pharmthera.2016.02.001. Epub 2016 Feb 16. Review.


Downregulation of Ca2+-activated Cl- channel TMEM16A by the inhibition of histone deacetylase in TMEM16A-expressing cancer cells.

Matsuba S, Niwa S, Muraki K, Kanatsuka S, Nakazono Y, Hatano N, Fujii M, Zhan P, Suzuki T, Ohya S.

J Pharmacol Exp Ther. 2014 Dec;351(3):510-8. doi: 10.1124/jpet.114.217315. Epub 2014 Sep 17.


Oseltamivir blocks human neuronal nicotinic acetylcholine receptor-mediated currents.

Muraki K, Hatano N, Suzuki H, Muraki Y, Iwajima Y, Maeda Y, Ono H.

Basic Clin Pharmacol Toxicol. 2015 Feb;116(2):87-95. doi: 10.1111/bcpt.12290. Epub 2014 Jul 31.


The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor.

Suzuki H, Hatano N, Muraki Y, Itoh Y, Kimura S, Hayashi H, Onozaki K, Ohi Y, Haji A, Muraki K.

Am J Physiol Cell Physiol. 2014 Aug 15;307(4):C384-94. doi: 10.1152/ajpcell.00182.2013. Epub 2014 Jun 18.


TRPV4 partially participates in proliferation of human brain capillary endothelial cells.

Hatano N, Suzuki H, Itoh Y, Muraki K.

Life Sci. 2013 Mar 12;92(4-5):317-24. doi: 10.1016/j.lfs.2013.01.002. Epub 2013 Jan 16.


Stimulation of human TRPA1 channels by clinical concentrations of the antirheumatic drug auranofin.

Hatano N, Suzuki H, Muraki Y, Muraki K.

Am J Physiol Cell Physiol. 2013 Feb 15;304(4):C354-61. doi: 10.1152/ajpcell.00096.2012. Epub 2012 Dec 5.


Hypoxia-inducible factor-1α (HIF1α) switches on transient receptor potential ankyrin repeat 1 (TRPA1) gene expression via a hypoxia response element-like motif to modulate cytokine release.

Hatano N, Itoh Y, Suzuki H, Muraki Y, Hayashi H, Onozaki K, Wood IC, Beech DJ, Muraki K.

J Biol Chem. 2012 Sep 14;287(38):31962-72. doi: 10.1074/jbc.M112.361139. Epub 2012 Jul 26.


Voltage-gated K+ currents in mouse articular chondrocytes regulate membrane potential.

Clark RB, Hatano N, Kondo C, Belke DD, Brown BS, Kumar S, Votta BJ, Giles WR.

Channels (Austin). 2010 May-Jun;4(3):179-91.


Accelerated Ca2+ entry by membrane hyperpolarization due to Ca2+-activated K+ channel activation in response to histamine in chondrocytes.

Funabashi K, Ohya S, Yamamura H, Hatano N, Muraki K, Giles W, Imaizumi Y.

Am J Physiol Cell Physiol. 2010 Apr;298(4):C786-97. doi: 10.1152/ajpcell.00469.2009. Epub 2009 Dec 30.


Cardiac fibroblasts have functional TRPV4 activated by 4alpha-phorbol 12,13-didecanoate.

Hatano N, Itoh Y, Muraki K.

Life Sci. 2009 Dec 16;85(23-26):808-14. doi: 10.1016/j.lfs.2009.10.013. Epub 2009 Oct 30.


An environmental sensor, TRPV4 is a novel regulator of intracellular Ca2+ in human synoviocytes.

Itoh Y, Hatano N, Hayashi H, Onozaki K, Miyazawa K, Muraki K.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1082-90. doi: 10.1152/ajpcell.00204.2009. Epub 2009 Sep 16.


TRPV4-like non-selective cation currents in cultured aortic myocytes.

Tanaka R, Muraki K, Ohya S, Yamamura H, Hatano N, Itoh Y, Imaizumi Y.

J Pharmacol Sci. 2008 Oct;108(2):179-89. Epub 2008 Oct 10.

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