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Items: 1 to 20 of 158

1.

Targeting airway inflammation in cystic fibrosis.

McElvaney OJ, Wade P, Murphy M, Reeves EP, McElvaney NG.

Expert Rev Respir Med. 2019 Sep 18. doi: 10.1080/17476348.2019.1666715. [Epub ahead of print]

PMID:
31530195
2.

Specific Inhibition of the NLRP3 Inflammasome as an Anti-Inflammatory Strategy in Cystic Fibrosis.

McElvaney OJ, Zaslona Z, Becker-Flegler K, Palsson-McDermott EM, Boland F, Gunaratnam C, Gulbins E, O'Neill LA, Reeves EP, McElvaney NG.

Am J Respir Crit Care Med. 2019 Aug 27. doi: 10.1164/rccm.201905-1013OC. [Epub ahead of print]

PMID:
31454256
3.

Pitfalls and caveats in α1-antitrypsin deficiency testing: a guide for clinicians.

Franciosi AN, Carroll TP, McElvaney NG.

Lancet Respir Med. 2019 Jul 16. pii: S2213-2600(19)30141-9. doi: 10.1016/S2213-2600(19)30141-9. [Epub ahead of print] Review.

PMID:
31324540
4.

The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes.

McKiernan PJ, Smith SGJ, Durham AL, Adcock IM, McElvaney NG, Greene CM.

J Innate Immun. 2019 Jul 2:1-13. doi: 10.1159/000500419. [Epub ahead of print]

5.

Characterisation of the Major Extracellular Proteases of Stenotrophomonas maltophilia and Their Effects on Pulmonary Antiproteases.

Molloy K, Smith SG, Cagney G, Dillon ET, Greene CM, McElvaney NG.

Pathogens. 2019 Jun 28;8(3). pii: E92. doi: 10.3390/pathogens8030092.

6.

Pneumothorax and lung cysts: a family affair.

Hawkins P, Logan PM, Reeves EP, McElvaney NG.

Lancet. 2019 Jun 29;393(10191):2635. doi: 10.1016/S0140-6736(19)31283-8. Epub 2019 Jun 27. No abstract available.

PMID:
31258130
7.

Assessment of stability and fluctuations of cultured lower airway bacterial communities in people with cystic fibrosis.

Sherrard LJ, Einarsson GG, Johnston E, O'Neill K, McIlreavey L, McGrath SJ, Gilpin DF, Downey DG, Reid A, McElvaney NG, Boucher RC, Muhlebach MS, Elborn JS, Tunney MM.

J Cyst Fibros. 2019 Mar 21. pii: S1569-1993(19)30052-9. doi: 10.1016/j.jcf.2019.02.012. [Epub ahead of print]

PMID:
30905581
8.

Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.

Reeves EP, Dunlea DM, McQuillan K, O'Dwyer CA, Carroll TP, Saldova R, Akepati PR, Wormald MR, McElvaney OJ, Shutchaidat V, Henry M, Meleady P, Keenan J, Liberti DC, Kotton DN, Rudd PM, Wilson AA, McElvaney NG.

J Immunol. 2019 Apr 15;202(8):2240-2253. doi: 10.4049/jimmunol.1801045. Epub 2019 Feb 22.

9.

The European Alpha-1 Research Collaboration (EARCO): a new ERS Clinical Research Collaboration to promote research in alpha-1 antitrypsin deficiency.

Miravitlles M, Chorostowska-Wynimko J, Ferrarotti I, McElvaney NG, O'Hara K, Stolk J, Stockley RA, Turner A, Wilkens M, Greulich T; EARCO Clinical Research Collaboration; Members of the EARCO Clinical Research Collaboration.

Eur Respir J. 2019 Feb 14;53(2). pii: 1900138. doi: 10.1183/13993003.00138-2019. Print 2019 Feb. No abstract available.

PMID:
30765486
10.

GDPR: an impediment to research?

Clarke N, Vale G, Reeves EP, Kirwan M, Smith D, Farrell M, Hurl G, McElvaney NG.

Ir J Med Sci. 2019 Feb 8. doi: 10.1007/s11845-019-01980-2. [Epub ahead of print]

PMID:
30734900
11.

Author Correction: α1-Antitrypsin deficiency.

Greene CM, Marciniak SJ, Teckman J, Ferrarotti I, Brantly ML, Lomas DA, Stoller JK, McElvaney NG.

Nat Rev Dis Primers. 2018 Oct 29;4(1):40. doi: 10.1038/s41572-018-0043-2.

PMID:
30374103
12.

Safety of biweekly α1-antitrypsin treatment in the RAPID programme.

Greulich T, Chlumsky J, Wencker M, Vit O, Fries M, Chung T, Shebl A, Vogelmeier C, Chapman KR, McElvaney NG; RAPID Trial Group.

Eur Respir J. 2018 Nov 29;52(5). pii: 1800897. doi: 10.1183/13993003.00897-2018. Print 2018 Nov. No abstract available.

13.

Emerging pharmacotherapies in cystic fibrosis.

McElvaney OJ, Gunaratnam C, McElvaney OF, Bagwe I, Reeves EP, McElvaney NG.

Expert Rev Respir Med. 2018 Oct;12(10):843-855. doi: 10.1080/17476348.2018.1512409. Epub 2018 Sep 19. Review.

PMID:
30129380
14.

Ataluren, a New Therapeutic for Alpha-1 Antitrypsin-Deficient Individuals with Nonsense Mutations.

Reeves EP, O'Dwyer CA, Dunlea DM, Wormald MR, Hawkins P, Alfares M, Kotton DN, Rowe SM, Wilson AA, McElvaney NG.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1099-1102. doi: 10.1164/rccm.201802-0338LE. No abstract available.

PMID:
30011228
15.

Anaerobic bacteria cultured from cystic fibrosis airways correlate to milder disease: a multisite study.

Muhlebach MS, Hatch JE, Einarsson GG, McGrath SJ, Gilipin DF, Lavelle G, Mirkovic B, Murray MA, McNally P, Gotman N, Davis Thomas S, Wolfgang MC, Gilligan PH, McElvaney NG, Elborn JS, Boucher RC, Tunney MM.

Eur Respir J. 2018 Jul 11;52(1). pii: 1800242. doi: 10.1183/13993003.00242-2018. Print 2018 Jul.

16.

Hermansky-Pudlak syndrome with a novel genetic variant in HPS1 and subsequent accelerated pulmonary fibrosis: significance for phenocopy diseases.

McElvaney OJ, Huizing M, Gahl WA, O'Donovan P, Horan D, Logan PM, Reeves EP, McElvaney NG.

Thorax. 2018 Nov;73(11):1085-1088. doi: 10.1136/thoraxjnl-2018-211920. Epub 2018 Jun 25.

PMID:
29941477
17.

Targeting IL-8 in Cystic Fibrosis: Enough but Not Too Much.

McElvaney OJ, McElvaney NG.

Am J Respir Cell Mol Biol. 2018 Oct;59(4):401-402. doi: 10.1165/rcmb.2018-0145ED. No abstract available.

PMID:
29723035
18.

The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus.

Sheehan G, Bergsson G, McElvaney NG, Reeves EP, Kavanagh K.

Infect Immun. 2018 Jun 21;86(7). pii: e00097-18. doi: 10.1128/IAI.00097-18. Print 2018 Jul.

19.

The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals.

Dunlea DM, Fee LT, McEnery T, McElvaney NG, Reeves EP.

J Inflamm Res. 2018 Mar 26;11:123-134. doi: 10.2147/JIR.S156405. eCollection 2018. Review.

20.

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing.

Clancy DM, Sullivan GP, Moran HBT, Henry CM, Reeves EP, McElvaney NG, Lavelle EC, Martin SJ.

Cell Rep. 2018 Mar 13;22(11):2937-2950. doi: 10.1016/j.celrep.2018.02.062.

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