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Differential regulation of cellular stress responses by the endoplasmic reticulum-resident Selenoprotein S (Seps1) in proliferating myoblasts versus myotubes.

Addinsall AB, Martin SD, Collier F, Conlan XA, Foletta VC, Stupka N.

Physiol Rep. 2018 Dec;6(24):e13926. doi: 10.14814/phy2.13926.


Deficiency of selenoprotein S, an endoplasmic reticulum resident oxidoreductase, impairs the contractile function of fast-twitch hindlimb muscles.

Addinsall AB, Wright CR, Shaw CS, McRae NL, Forgan LG, Weng CH, Conlan XA, Francis PS, Smith ZM, Andrikopoulos S, Stupka N.

Am J Physiol Regul Integr Comp Physiol. 2018 Aug 1;315(2):R380-R396. doi: 10.1152/ajpregu.00244.2017. Epub 2018 Apr 18.


Emerging roles of endoplasmic reticulum-resident selenoproteins in the regulation of cellular stress responses and the implications for metabolic disease.

Addinsall AB, Wright CR, Andrikopoulos S, van der Poel C, Stupka N.

Biochem J. 2018 Mar 20;475(6):1037-1057. doi: 10.1042/BCJ20170920. Review.


The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation.

Dancevic CM, Gibert Y, Berger J, Smith AD, Liongue C, Stupka N, Ward AC, McCulloch DR.

Int J Mol Sci. 2018 Mar 7;19(3). pii: E766. doi: 10.3390/ijms19030766.


Large and Small Assembly: Combining Functional Macromolecules with Small Peptides to Control the Morphology of Skeletal Muscle Progenitor Cells.

Li R, McRae NL, McCulloch DR, Boyd-Moss M, Barrow CJ, Nisbet DR, Stupka N, Williams RJ.

Biomacromolecules. 2018 Mar 12;19(3):825-837. doi: 10.1021/acs.biomac.7b01632. Epub 2018 Feb 13.


Glucocorticoids Improve Myogenic Differentiation In Vitro by Suppressing the Synthesis of Versican, a Transitional Matrix Protein Overexpressed in Dystrophic Skeletal Muscles.

McRae N, Forgan L, McNeill B, Addinsall A, McCulloch D, Van der Poel C, Stupka N.

Int J Mol Sci. 2017 Dec 6;18(12). pii: E2629. doi: 10.3390/ijms18122629.


A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in the mdx Dystrophic Mouse.

Wright CR, Allsopp GL, Addinsall AB, McRae NL, Andrikopoulos S, Stupka N.

Mediators Inflamm. 2017;2017:7043429. doi: 10.1155/2017/7043429. Epub 2017 May 16.


Characterisation of minimalist co-assembled fluorenylmethyloxycarbonyl self-assembling peptide systems for presentation of multiple bioactive peptides.

Horgan CC, Rodriguez AL, Li R, Bruggeman KF, Stupka N, Raynes JK, Day L, White JW, Williams RJ, Nisbet DR.

Acta Biomater. 2016 Jul 1;38:11-22. doi: 10.1016/j.actbio.2016.04.038. Epub 2016 Apr 27.


Sarcopenia and the Common Mental Disorders: a Potential Regulatory Role of Skeletal Muscle on Brain Function?

Pasco JA, Williams LJ, Jacka FN, Stupka N, Brennan-Olsen SL, Holloway KL, Berk M.

Curr Osteoporos Rep. 2015 Oct;13(5):351-7. doi: 10.1007/s11914-015-0279-7. Review.


Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15: a novel versican-cleaving proteoglycanase.

Dancevic CM, Fraser FW, Smith AD, Stupka N, Ward AC, McCulloch DR.

J Biol Chem. 2013 Dec 27;288(52):37267-76. doi: 10.1074/jbc.M112.418624. Epub 2013 Nov 12.


Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion.

Stupka N, Kintakas C, White JD, Fraser FW, Hanciu M, Aramaki-Hattori N, Martin S, Coles C, Collier F, Ward AC, Apte SS, McCulloch DR.

J Biol Chem. 2013 Jan 18;288(3):1907-17. doi: 10.1074/jbc.M112.429647. Epub 2012 Dec 11.


Determination of intracellular glutathione and glutathione disulfide using high performance liquid chromatography with acidic potassium permanganate chemiluminescence detection.

McDermott GP, Francis PS, Holt KJ, Scott KL, Martin SD, Stupka N, Barnett NW, Conlan XA.

Analyst. 2011 Jun 21;136(12):2578-85. doi: 10.1039/c1an00004g. Epub 2011 Mar 11.


Enhanced proliferation of human skeletal muscle precursor cells derived from elderly donors cultured in estimated physiological (5%) oxygen.

Martin SD, Collier FM, Kirkland MA, Walder K, Stupka N.

Cytotechnology. 2009 Dec;61(3):93-107. doi: 10.1007/s10616-009-9247-3. Epub 2010 Jan 22.


Determination of intracellular glutathione and cysteine using HPLC with a monolithic column after derivatization with monobromobimane.

Conlan XA, Stupka N, McDermott GP, Francis PS, Barnett NW.

Biomed Chromatogr. 2010 May;24(5):455-7. doi: 10.1002/bmc.1327.


Comments on Point:Counterpoint: Estrogen and sex do/do not influence post-exercise indexes of muscle damage, inflammation, and repair.

Pizza FX, Clark BC, De Meersman RE, Phillips SM, Stupka N, Sipila S, Kovanen V, Suominen H, Warren GL, Lowe DA, Miles MP, Sorichter S, Walterspacher S, Sayers SP, Savage KJ.

J Appl Physiol (1985). 2009 Mar;106(3):1016-20. doi: 10.1152/japplphysiol.00004.2009. No abstract available.


NDRG2, a novel regulator of myoblast proliferation, is regulated by anabolic and catabolic factors.

Foletta VC, Prior MJ, Stupka N, Carey K, Segal DH, Jones S, Swinton C, Martin S, Cameron-Smith D, Walder KR.

J Physiol. 2009 Apr 1;587(Pt 7):1619-34. doi: 10.1113/jphysiol.2008.167882. Epub 2009 Feb 9.


Stimulation of calcineurin Aalpha activity attenuates muscle pathophysiology in mdx dystrophic mice.

Stupka N, Schertzer JD, Bassel-Duby R, Olson EN, Lynch GS.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R983-92. doi: 10.1152/ajpregu.00375.2007. Epub 2008 Jan 16.


Calcineurin-A alpha activation enhances the structure and function of regenerating muscles after myotoxic injury.

Stupka N, Schertzer JD, Bassel-Duby R, Olson EN, Lynch GS.

Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R686-94. Epub 2007 May 2.


Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice.

Stupka N, Plant DR, Schertzer JD, Emerson TM, Bassel-Duby R, Olson EN, Lynch GS.

J Physiol. 2006 Sep 1;575(Pt 2):645-56. Epub 2006 Jun 22.


Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice.

Stupka N, Michell BJ, Kemp BE, Lynch GS.

Neuromuscul Disord. 2006 May;16(5):337-46. Epub 2006 Apr 18.


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