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Items: 1 to 20 of 82

1.

The Function of Lgr5+ Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo.

Flanagan D, Barker N, Ernst M, Vincan E, Phesse T.

Biomedicines. 2019 Jul 8;7(3). pii: E50. doi: 10.3390/biomedicines7030050.

2.

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.

Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K.

Int J Mol Sci. 2019 Jun 17;20(12). pii: E2955. doi: 10.3390/ijms20122955.

3.

Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo.

Xue Y, Barker N, Hoon S, He P, Thakur T, Abdeen SR, Maruthappan P, Ghadessy FJ, Lane DP.

Cancer Res. 2019 Jul 15;79(14):3595-3607. doi: 10.1158/0008-5472.CAN-18-3744. Epub 2019 May 28.

PMID:
31138526
4.

A contemporary snapshot of intestinal stem cells and their regulation.

Seishima R, Barker N.

Differentiation. 2019 Jan 25. pii: S0301-4681(18)30147-6. doi: 10.1016/j.diff.2019.01.004. [Epub ahead of print] Review.

PMID:
30711339
5.

Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.

Flanagan DJ, Barker N, Costanzo NSD, Mason EA, Gurney A, Meniel VS, Koushyar S, Austin CR, Ernst M, Pearson HB, Boussioutas A, Clevers H, Phesse TJ, Vincan E.

Cancer Res. 2019 Mar 1;79(5):970-981. doi: 10.1158/0008-5472.CAN-18-2095. Epub 2019 Jan 8.

PMID:
30622113
6.

Author Correction: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.

Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefèvre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Başaran S, Yücel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B.

Nature. 2018 Sep;561(7722):E7. doi: 10.1038/s41586-018-0296-7.

PMID:
29977062
7.

RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.

Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefèvre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Başaran S, Yücel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B.

Nature. 2018 May;557(7706):564-569. doi: 10.1038/s41586-018-0118-y. Epub 2018 May 16. Erratum in: Nature. 2018 Sep;561(7722):E7.

PMID:
29769720
8.

Recent Advances in Lgr5+ Stem Cell Research.

Leung C, Tan SH, Barker N.

Trends Cell Biol. 2018 May;28(5):380-391. doi: 10.1016/j.tcb.2018.01.010. Epub 2018 Feb 21. Review.

PMID:
29477614
9.

The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy.

Vincan E, Schwab RHM, Flanagan DJ, Moselen JM, Tran BM, Barker N, Phesse TJ.

Prog Mol Biol Transl Sci. 2018 Jan;153:299-319. doi: 10.1016/bs.pmbts.2017.11.009. Epub 2017 Dec 21. Review.

PMID:
29389521
10.

Wnt Signaling in Adult Epithelial Stem Cells and Cancer.

Tan SH, Barker N.

Prog Mol Biol Transl Sci. 2018 Jan;153:21-79. doi: 10.1016/bs.pmbts.2017.11.017. Epub 2018 Jan 8. Review.

PMID:
29389518
11.

Stem cells in 2017: Digesting recent stem cell advances in the gut.

Barker N.

Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):78-80. doi: 10.1038/nrgastro.2017.176. Epub 2018 Jan 4. No abstract available.

PMID:
29300047
12.

Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.

Huang KK, Ramnarayanan K, Zhu F, Srivastava S, Xu C, Tan ALK, Lee M, Tay S, Das K, Xing M, Fatehullah A, Alkaff SMF, Lim TKH, Lee J, Ho KY, Rozen SG, Teh BT, Barker N, Chia CK, Khor C, Ooi CJ, Fock KM, So J, Lim WC, Ling KL, Ang TL, Wong A, Rao J, Rajnakova A, Lim LG, Yap WM, Teh M, Yeoh KG, Tan P.

Cancer Cell. 2018 Jan 8;33(1):137-150.e5. doi: 10.1016/j.ccell.2017.11.018. Epub 2017 Dec 28.

13.

Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo.

Flanagan DJ, Barker N, Nowell C, Clevers H, Ernst M, Phesse TJ, Vincan E.

Dis Model Mech. 2017 Aug 1;10(8):971-980. doi: 10.1242/dmm.029876. Epub 2017 Jun 9.

14.

Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach.

Leushacke M, Tan SH, Wong A, Swathi Y, Hajamohideen A, Tan LT, Goh J, Wong E, Denil SLIJ, Murakami K, Barker N.

Nat Cell Biol. 2017 Jul;19(7):774-786. doi: 10.1038/ncb3541. Epub 2017 Jun 5.

PMID:
28581476
15.

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma.

Cammareri P, Rose AM, Vincent DF, Wang J, Nagano A, Libertini S, Ridgway RA, Athineos D, Coates PJ, McHugh A, Pourreyron C, Dayal JH, Larsson J, Weidlich S, Spender LC, Sapkota GP, Purdie KJ, Proby CM, Harwood CA, Leigh IM, Clevers H, Barker N, Karlsson S, Pritchard C, Marais R, Chelala C, South AP, Sansom OJ, Inman GJ.

Nat Commun. 2016 Aug 25;7:12493. doi: 10.1038/ncomms12493.

16.

Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium.

Leushacke M, Barker N, Pin C.

Sci Rep. 2016 Feb 26;6:21923. doi: 10.1038/srep21923.

17.

Organoids as an in vitro model of human development and disease.

Fatehullah A, Tan SH, Barker N.

Nat Cell Biol. 2016 Mar;18(3):246-54. doi: 10.1038/ncb3312. Review.

PMID:
26911908
18.

Stemming Colorectal Cancer Growth and Metastasis: HOXA5 Forces Cancer Stem Cells to Differentiate.

Tan SH, Barker N.

Cancer Cell. 2015 Dec 14;28(6):683-685. doi: 10.1016/j.ccell.2015.11.004.

19.

Ovary and fimbrial stem cells: biology, niche and cancer origins.

Ng A, Barker N.

Nat Rev Mol Cell Biol. 2015 Oct;16(10):625-38. doi: 10.1038/nrm4056. Epub 2015 Sep 9. Review.

PMID:
26350076
20.

Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice.

Goh AM, Xue Y, Leushacke M, Li L, Wong JS, Chiam PC, Rahmat SA, Mann MB, Mann KM, Barker N, Lozano G, Terzian T, Lane DP.

Oncotarget. 2015 Jul 20;6(20):17968-80.

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