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Items: 1 to 20 of 66

1.

High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches.

Slagboom J, Mladić M, Xie C, Kazandjian TD, Vonk F, Somsen GW, Casewell NR, Kool J.

PLoS Negl Trop Dis. 2020 Apr 1;14(4):e0007802. doi: 10.1371/journal.pntd.0007802. [Epub ahead of print]

2.

Development of a generic high-throughput screening assay for profiling snake venom protease activity after high-resolution chromatographic fractionation.

Neumann C, Slagboom J, Somsen GW, Vonk F, Casewell NR, Cardoso CL, Kool J.

Toxicon. 2020 Apr 30;178:61-68. doi: 10.1016/j.toxicon.2020.02.015. Epub 2020 Feb 26.

PMID:
32112787
3.

Venomics of the asp viper Vipera aspis aspis from France.

Giribaldi J, Kazandjian T, Amorim FG, Whiteley G, Wagstaff SC, Cazals G, Enjalbal C, Quinton L, Casewell NR, Dutertre S.

J Proteomics. 2020 Apr 30;218:103707. doi: 10.1016/j.jprot.2020.103707. Epub 2020 Feb 19.

PMID:
32087377
4.

Snake Venom Gland Organoids.

Post Y, Puschhof J, Beumer J, Kerkkamp HM, de Bakker MAG, Slagboom J, de Barbanson B, Wevers NR, Spijkers XM, Olivier T, Kazandjian TD, Ainsworth S, Iglesias CL, van de Wetering WJ, Heinz MC, van Ineveld RL, van Kleef RGDM, Begthel H, Korving J, Bar-Ephraim YE, Getreuer W, Rios AC, Westerink RHS, Snippert HJG, van Oudenaarden A, Peters PJ, Vonk FJ, Kool J, Richardson MK, Casewell NR, Clevers H.

Cell. 2020 Jan 23;180(2):233-247.e21. doi: 10.1016/j.cell.2019.11.038.

PMID:
31978343
5.

Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics.

Xie C, Slagboom J, Albulescu LO, Bruyneel B, Still KBM, Vonk FJ, Somsen GW, Casewell NR, Kool J.

Toxins (Basel). 2020 Jan 16;12(1). pii: E53. doi: 10.3390/toxins12010053.

6.

Mapping Enzyme Activity on Tissue by Functional Mass Spectrometry Imaging.

Hamilton BR, Marshall DL, Casewell NR, Harrison RA, Blanksby SJ, Undheim EAB.

Angew Chem Int Ed Engl. 2020 Mar 2;59(10):3855-3858. doi: 10.1002/anie.201911390. Epub 2020 Jan 23.

7.

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals.

Casewell NR, Petras D, Card DC, Suranse V, Mychajliw AM, Richards D, Koludarov I, Albulescu LO, Slagboom J, Hempel BF, Ngum NM, Kennerley RJ, Brocca JL, Whiteley G, Harrison RA, Bolton FMS, Debono J, Vonk FJ, Alföldi J, Johnson J, Karlsson EK, Lindblad-Toh K, Mellor IR, Süssmuth RD, Fry BG, Kuruppu S, Hodgson WC, Kool J, Castoe TA, Barnes I, Sunagar K, Undheim EAB, Turvey ST.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25745-25755. doi: 10.1073/pnas.1906117116. Epub 2019 Nov 26.

8.

Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity.

Chaisakul J, Alsolaiss J, Charoenpitakchai M, Wiwatwarayos K, Sookprasert N, Harrison RA, Chaiyabutr N, Chanhome L, Tan CH, Casewell NR.

PLoS Negl Trop Dis. 2019 Oct 23;13(10):e0007338. doi: 10.1371/journal.pntd.0007338. eCollection 2019 Oct.

9.

A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite.

Albulescu LO, Kazandjian T, Slagboom J, Bruyneel B, Ainsworth S, Alsolaiss J, Wagstaff SC, Whiteley G, Harrison RA, Ulens C, Kool J, Casewell NR.

Front Pharmacol. 2019 Jul 30;10:848. doi: 10.3389/fphar.2019.00848. eCollection 2019.

10.

Bioactivity Profiling of Small-Volume Samples by Nano Liquid Chromatography Coupled to Microarray Bioassaying Using High-Resolution Fractionation.

Zietek BM, Still KBM, Jaschusch K, Bruyneel B, Ariese F, Brouwer TJF, Luger M, Limburg RJ, Rosier JC, V Iperen DJ, Casewell NR, Somsen GW, Kool J.

Anal Chem. 2019 Aug 20;91(16):10458-10466. doi: 10.1021/acs.analchem.9b01261. Epub 2019 Aug 2.

11.

Intact protein mass spectrometry reveals intraspecies variations in venom composition of a local population of Vipera kaznakovi in Northeastern Turkey.

Petras D, Hempel BF, Göçmen B, Karis M, Whiteley G, Wagstaff SC, Heiss P, Casewell NR, Nalbantsoy A, Süssmuth RD.

J Proteomics. 2019 May 15;199:31-50. doi: 10.1016/j.jprot.2019.02.004. Epub 2019 Feb 11.

PMID:
30763806
12.

The time is now: a call for action to translate recent momentum on tackling tropical snakebite into sustained benefit for victims.

Harrison RA, Casewell NR, Ainsworth SA, Lalloo DG.

Trans R Soc Trop Med Hyg. 2019 Dec 1;113(12):835-838. doi: 10.1093/trstmh/try134.

13.

Friends or Foes? Emerging Impacts of Biological Toxins.

Clark GC, Casewell NR, Elliott CT, Harvey AL, Jamieson AG, Strong PN, Turner AD.

Trends Biochem Sci. 2019 Apr;44(4):365-379. doi: 10.1016/j.tibs.2018.12.004. Epub 2019 Jan 14. Review.

14.

Defining the pathogenic threat of envenoming by South African shield-nosed and coral snakes (genus Aspidelaps), and revealing the likely efficacy of available antivenom.

Whiteley G, Casewell NR, Pla D, Quesada-Bernat S, Logan RAE, Bolton FMS, Wagstaff SC, Gutiérrez JM, Calvete JJ, Harrison RA.

J Proteomics. 2019 Apr 30;198:186-198. doi: 10.1016/j.jprot.2018.09.019. Epub 2018 Oct 2.

PMID:
30290233
15.

The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms.

Ainsworth S, Slagboom J, Alomran N, Pla D, Alhamdi Y, King SI, Bolton FMS, Gutiérrez JM, Vonk FJ, Toh CH, Calvete JJ, Kool J, Harrison RA, Casewell NR.

Commun Biol. 2018 Apr 19;1:34. doi: 10.1038/s42003-018-0039-1. eCollection 2018.

16.

Liquid chromatographic nanofractionation with parallel mass spectrometric detection for the screening of plasmin inhibitors and (metallo)proteinases in snake venoms.

Zietek BM, Mayar M, Slagboom J, Bruyneel B, Vonk FJ, Somsen GW, Casewell NR, Kool J.

Anal Bioanal Chem. 2018 Sep;410(23):5751-5763. doi: 10.1007/s00216-018-1253-x. Epub 2018 Aug 9.

17.

Molecular Adaptations for Sensing and Securing Prey and Insight into Amniote Genome Diversity from the Garter Snake Genome.

Perry BW, Card DC, McGlothlin JW, Pasquesi GIM, Adams RH, Schield DR, Hales NR, Corbin AB, Demuth JP, Hoffmann FG, Vandewege MW, Schott RK, Bhattacharyya N, Chang BSW, Casewell NR, Whiteley G, Reyes-Velasco J, Mackessy SP, Gamble T, Storey KB, Biggar KK, Passow CN, Kuo CH, McGaugh SE, Bronikowski AM, de Koning APJ, Edwards SV, Pfrender ME, Minx P, Brodie ED 3rd, Brodie ED Jr, Warren WC, Castoe TA.

Genome Biol Evol. 2018 Aug 1;10(8):2110-2129. doi: 10.1093/gbe/evy157.

18.

Rapid ligand fishing for identification of acetylcholinesterase-binding peptides in snake venom reveals new properties of dendrotoxins.

Vanzolini KL, Ainsworth S, Bruyneel B, Herzig V, Seraus MGL, Somsen GW, Casewell NR, Cass QB, Kool J.

Toxicon. 2018 Sep 15;152:1-8. doi: 10.1016/j.toxicon.2018.06.080. Epub 2018 Jul 7.

19.

Widespread vulnerability of Malagasy predators to the toxins of an introduced toad.

Marshall BM, Casewell NR, Vences M, Glaw F, Andreone F, Rakotoarison A, Zancolli G, Woog F, Wüster W.

Curr Biol. 2018 Jul 9;28(13):2194. doi: 10.1016/j.cub.2018.06.012. No abstract available.

20.

Widespread vulnerability of Malagasy predators to the toxins of an introduced toad.

Marshall BM, Casewell NR, Vences M, Glaw F, Andreone F, Rakotoarison A, Zancolli G, Woog F, Wüster W.

Curr Biol. 2018 Jun 4;28(11):R654-R655. doi: 10.1016/j.cub.2018.04.024. Erratum in: Curr Biol. 2018 Jul 9;28(13):2194.

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