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Items: 17


TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines.

Cikutović-Molina R, Herrada AA, González W, Brown N, Zúñiga L.

Int J Mol Sci. 2019 Dec 2;20(23). pii: E6077. doi: 10.3390/ijms20236077.


SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells.

Valenzuela CA, Quintanilla R, Olate-Briones A, Venturini W, Mancilla D, Cayo A, Moore-Carrasco R, Brown NE.

Int J Mol Sci. 2019 Oct 24;20(21). pii: E5292. doi: 10.3390/ijms20215292.


Adenosine Derivates as Antioxidant Agents: Synthesis, Characterization, in Vitro Activity, and Theoretical Insights.

Valdes F, Brown N, Morales-Bayuelo A, Prent-Peñaloza L, Gutierrez M.

Antioxidants (Basel). 2019 Oct 9;8(10). pii: E468. doi: 10.3390/antiox8100468.


Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity.

Valdés FZ, Luna VZ, Arévalo BR, Brown NV, Gutiérrez MC.

Mini Rev Med Chem. 2018;18(20):1684-1701. doi: 10.2174/1389557518666180516163539. Review.


TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines.

Zúñiga R, Valenzuela C, Concha G, Brown N, Zúñiga L.

Int J Mol Sci. 2018 Mar 29;19(4). pii: E1033. doi: 10.3390/ijms19041033.


Palbociclib-induced autophagy and senescence in gastric cancer cells.

Valenzuela CA, Vargas L, Martinez V, Bravo S, Brown NE.

Exp Cell Res. 2017 Nov 15;360(2):390-396. doi: 10.1016/j.yexcr.2017.09.031. Epub 2017 Sep 23.


Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.

Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS, Tirschwell DL; RESPECT Investigators.

N Engl J Med. 2017 Sep 14;377(11):1022-1032. doi: 10.1056/NEJMoa1610057.


The Potential Role of Senescence As a Modulator of Platelets and Tumorigenesis.

Valenzuela CA, Quintanilla R, Moore-Carrasco R, Brown NE.

Front Oncol. 2017 Aug 28;7:188. doi: 10.3389/fonc.2017.00188. eCollection 2017.


Expression and cellular localization of HCN channels in rat cerebellar granule neurons.

Zúñiga R, González D, Valenzuela C, Brown N, Zúñiga L.

Biochem Biophys Res Commun. 2016 Sep 23;478(3):1429-35. doi: 10.1016/j.bbrc.2016.08.141. Epub 2016 Aug 25.


Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.

Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, Blasco MA, Hinds PW, Kuperwasser C.

Nat Commun. 2015 Jun 24;6:7505. doi: 10.1038/ncomms8505.


The selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia.

Echiburú-Chau C, Alfaro-Lira S, Brown N, Salas CO, Cuellar M, Santander J, Ogalde JP, Rothhammer F.

Int J Oncol. 2014 Apr;44(4):1357-64. doi: 10.3892/ijo.2014.2302. Epub 2014 Feb 14.


Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.

Brown NE, Jeselsohn R, Bihani T, Hu MG, Foltopoulou P, Kuperwasser C, Hinds PW.

Cancer Res. 2012 Dec 15;72(24):6477-89. doi: 10.1158/0008-5472.CAN-11-4139. Epub 2012 Oct 4.


Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis.

Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C, Hinds PW.

Cancer Cell. 2010 Jan 19;17(1):65-76. doi: 10.1016/j.ccr.2009.11.024.


Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.

Gutierrez GM, Kong E, Sabbagh Y, Brown NE, Lee JS, Demay MB, Thomas DM, Hinds PW.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18402-7. doi: 10.1073/pnas.0805925105. Epub 2008 Nov 19.


The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development.

Landis MW, Brown NE, Baker GL, Shifrin A, Das M, Geng Y, Sicinski P, Hinds PW.

Cancer Res. 2007 Aug 15;67(16):7613-20.


A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats.

Gallagher AR, Hoffmann S, Brown N, Cedzich A, Meruvu S, Podlich D, Feng Y, Könecke V, de Vries U, Hammes HP, Gretz N, Witzgall R.

J Am Soc Nephrol. 2006 Oct;17(10):2719-30. Epub 2006 Aug 30.


Use of the tetracycline system for inducible protein synthesis in the kidney.

Gallagher AR, Schönig K, Brown N, Bujard H, Witzgall R.

J Am Soc Nephrol. 2003 Aug;14(8):2042-51.

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