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Items: 1 to 20 of 112

1.

Replicating predictive serum correlates of greater translocator protein distribution volume in brain.

Attwells S, Setiawan E, Wilson AA, Rusjan PM, Miler L, Xu C, Hutton C, Husain MI, Kish S, Vasdev N, Houle S, Meyer JH.

Neuropsychopharmacology. 2019 Nov 4. doi: 10.1038/s41386-019-0561-y. [Epub ahead of print]

PMID:
31683271
2.

Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.

Bernard-Gauthier V, Mossine AV, Knight A, Patnaik D, Zhao WN, Cheng C, Krishnan HS, Xuan LL, Chindavong PS, Reis SA, Chen JM, Shao X, Stauff J, Arteaga J, Sherman P, Salem N, Bonsall D, Amaral B, Varlow C, Wells L, Martarello L, Patel S, Liang SH, Kurumbail RG, Haggarty SJ, Scott PJH, Vasdev N.

J Med Chem. 2019 Nov 14;62(21):9600-9617. doi: 10.1021/acs.jmedchem.9b01030. Epub 2019 Oct 21.

3.

Improving PET Imaging Acquisition and Analysis With Machine Learning: A Narrative Review With Focus on Alzheimer's Disease and Oncology.

Duffy IR, Boyle AJ, Vasdev N.

Mol Imaging. 2019 Jan-Dec;18:1536012119869070. doi: 10.1177/1536012119869070.

4.

Engineered antibodies: new possibilities for brain PET?

Sehlin D, Syvänen S; MINC faculty.

Eur J Nucl Med Mol Imaging. 2019 Dec;46(13):2848-2858. doi: 10.1007/s00259-019-04426-0. Epub 2019 Jul 24.

5.

"In-loop" 18 F-fluorination: A proof-of-concept study.

Dahl K, Garcia A, Stephenson NA, Vasdev N.

J Labelled Comp Radiopharm. 2019 Jun 15;62(7):292-297. doi: 10.1002/jlcr.3751.

PMID:
31083778
6.

Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B.

Dahl K, Bernard-Gauthier V, Nag S, Varnäs K, Narayanaswami V, Mahdi Moein M, Arakawa R, Vasdev N, Halldin C.

Bioorg Med Chem Lett. 2019 Jul 1;29(13):1624-1627. doi: 10.1016/j.bmcl.2019.04.040. Epub 2019 Apr 27.

PMID:
31060887
7.

Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB.

Liang SH, Wang L, Stephenson NA, Rotstein BH, Vasdev N.

Nat Protoc. 2019 May;14(5):1530-1545. doi: 10.1038/s41596-019-0149-3. Epub 2019 Apr 12.

PMID:
30980032
8.

Monoamine Oxidase B Total Distribution Volume in the Prefrontal Cortex of Major Depressive Disorder: An [11C]SL25.1188 Positron Emission Tomography Study.

Moriguchi S, Wilson AA, Miler L, Rusjan PM, Vasdev N, Kish SJ, Rajkowska G, Wang J, Bagby M, Mizrahi R, Varughese B, Houle S, Meyer JH.

JAMA Psychiatry. 2019 Jun 1;76(6):634-641. doi: 10.1001/jamapsychiatry.2019.0044. Erratum in: JAMA Psychiatry. 2019 Apr 10;:.

PMID:
30840042
9.

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.

Chen Z, Mori W, Deng X, Cheng R, Ogasawara D, Zhang G, Schafroth MA, Dahl K, Fu H, Hatori A, Shao T, Zhang Y, Yamasaki T, Zhang X, Rong J, Yu Q, Hu K, Fujinaga M, Xie L, Kumata K, Gou Y, Chen J, Gu S, Bao L, Wang L, Collier TL, Vasdev N, Shao Y, Ma JA, Cravatt BF, Fowler C, Josephson L, Zhang MR, Liang SH.

J Med Chem. 2019 Apr 11;62(7):3336-3353. doi: 10.1021/acs.jmedchem.8b01778. Epub 2019 Mar 21.

PMID:
30829483
10.

Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases.

Narayanaswami V, Drake LR, Brooks AF, Meyer JH, Houle S, Kilbourn MR, Scott PJH, Vasdev N.

ACS Chem Neurosci. 2019 Apr 17;10(4):1867-1871. doi: 10.1021/acschemneuro.9b00081. Epub 2019 Feb 21.

PMID:
30789704
11.

Recent applications of a single quadrupole mass spectrometer in 11C, 18F and radiometal chemistry.

Collier TL, Dahl K, Stephenson NA, Holland JP, Riley A, Liang SH, Vasdev N.

J Fluor Chem. 2018 Jun;210:46-55. doi: 10.1016/j.jfluchem.2018.02.009. Epub 2018 Mar 5.

12.

The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils.

Josephson L, Stratman N, Liu Y, Qian F, Liang SH, Vasdev N, Patel S.

Mol Imaging. 2018 Jan-Dec;17:1536012118796297. doi: 10.1177/1536012118796297.

13.

Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO.

Narayanaswami V, Dahl K, Bernard-Gauthier V, Josephson L, Cumming P, Vasdev N.

Mol Imaging. 2018 Jan-Dec;17:1536012118792317. doi: 10.1177/1536012118792317. Review.

14.

Fluorine-18: an untapped resource in inorganic chemistry.

Varlow C, Szames D, Dahl K, Bernard-Gauthier V, Vasdev N.

Chem Commun (Camb). 2018 Oct 18;54(84):11835-11842. doi: 10.1039/c8cc04751k.

15.

Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions.

Deng X, Rong J, Wang L, Vasdev N, Zhang L, Josephson L, Liang SH.

Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2580-2605. doi: 10.1002/anie.201805501. Epub 2019 Jan 14. Review.

PMID:
30054961
16.

Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors.

Collier TL, Liang SH, Mann JJ, Vasdev N, Kumar JSD.

Beilstein J Org Chem. 2017 Dec 29;13:2922-2927. doi: 10.3762/bjoc.13.285. eCollection 2017.

17.

In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.

Cheng R, Mori W, Ma L, Alhouayek M, Hatori A, Zhang Y, Ogasawara D, Yuan G, Chen Z, Zhang X, Shi H, Yamasaki T, Xie L, Kumata K, Fujinaga M, Nagai Y, Minamimoto T, Svensson M, Wang L, Du Y, Ondrechen MJ, Vasdev N, Cravatt BF, Fowler C, Zhang MR, Liang SH.

J Med Chem. 2018 Mar 22;61(6):2278-2291. doi: 10.1021/acs.jmedchem.7b01400. Epub 2018 Mar 9.

18.

Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [11C]PBT2.

Krishnan HS, Bernard-Gauthier V, Placzek MS, Dahl K, Narayanaswami V, Livni E, Chen Z, Yang J, Collier TL, Ran C, Hooker JM, Liang SH, Vasdev N.

Mol Pharm. 2018 Feb 5;15(2):695-702. doi: 10.1021/acs.molpharmaceut.7b00936. Epub 2018 Jan 22.

PMID:
29298483
19.

Recent Advances in 18F Radiochemistry: A Focus on B-18F, Si-18F, Al-18F, and C-18F Radiofluorination via Spirocyclic Iodonium Ylides.

Bernard-Gauthier V, Lepage ML, Waengler B, Bailey JJ, Liang SH, Perrin DM, Vasdev N, Schirrmacher R.

J Nucl Med. 2018 Apr;59(4):568-572. doi: 10.2967/jnumed.117.197095. Epub 2017 Dec 28. Review.

20.

Sifting through the surfeit of neuroinflammation tracers.

Cumming P, Burgher B, Patkar O, Breakspear M, Vasdev N, Thomas P, Liu GJ, Banati R.

J Cereb Blood Flow Metab. 2018 Feb;38(2):204-224. doi: 10.1177/0271678X17748786. Epub 2017 Dec 19. Review.

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