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Items: 12


Neuroprotection Comparison of Rosmarinic Acid and Carnosic Acid in Primary Cultures of Cerebellar Granule Neurons.

Taram F, Ignowski E, Duval N, Linseman DA.

Molecules. 2018 Nov 13;23(11). pii: E2956. doi: 10.3390/molecules23112956.


Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging.

Duval N, Vacano GN, Patterson D.

Front Aging Neurosci. 2018 Sep 6;10:263. doi: 10.3389/fnagi.2018.00263. eCollection 2018.


The cysteine-rich whey protein supplement, Immunocal®, preserves brain glutathione and improves cognitive, motor, and histopathological indices of traumatic brain injury in a mouse model of controlled cortical impact.

Ignowski E, Winter AN, Duval N, Fleming H, Wallace T, Manning E, Koza L, Huber K, Serkova NJ, Linseman DA.

Free Radic Biol Med. 2018 Aug 20;124:328-341. doi: 10.1016/j.freeradbiomed.2018.06.026. Epub 2018 Jun 27.


The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord.

Duval N, Sumner WA, Andrianakos AG, Gray JJ, Bouchard RJ, Wilkins HM, Linseman DA.

Front Cell Neurosci. 2018 Jan 30;12:15. doi: 10.3389/fncel.2018.00015. eCollection 2018.


Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome.

Hamlett ED, Boger HA, Ledreux A, Kelley CM, Mufson EJ, Falangola MF, Guilfoyle DN, Nixon RA, Patterson D, Duval N, Granholm AC.

Curr Alzheimer Res. 2016;13(1):35-52. Review.


A Cystine-Rich Whey Supplement (Immunocal(®)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.

Ross EK, Winter AN, Wilkins HM, Sumner WA, Duval N, Patterson D, Linseman DA.

Antioxidants (Basel). 2014 Dec 12;3(4):843-65. doi: 10.3390/antiox3040843.


Inherent properties of adenylosuccinate lyase could explain S-Ado/SAICAr ratio due to homozygous R426H and R303C mutations.

Ray SP, Duval N, Wilkinson TG 2nd, Shaheen SE, Ghosh K, Patterson D.

Biochim Biophys Acta. 2013 Aug;1834(8):1545-53. doi: 10.1016/j.bbapap.2013.05.013. Epub 2013 May 25.


Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.

Duval N, Luhrs K, Wilkinson TG 2nd, Baresova V, Skopova V, Kmoch S, Vacano GN, Zikanova M, Patterson D.

Mol Genet Metab. 2013 Mar;108(3):178-189. doi: 10.1016/j.ymgme.2013.01.002. Epub 2013 Jan 12.


N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress.

Gray JJ, Zommer AE, Bouchard RJ, Duval N, Blackstone C, Linseman DA.

Brain Res. 2013 Feb 4;1494:28-43. doi: 10.1016/j.brainres.2012.12.001. Epub 2012 Dec 7.


The use of mouse models for understanding the biology of down syndrome and aging.

Vacano GN, Duval N, Patterson D.

Curr Gerontol Geriatr Res. 2012;2012:717315. doi: 10.1155/2012/717315. Epub 2012 Feb 23.


Persistence of Bacillus thuringiensis subsp. kurstaki in Urban Environments following Spraying.

Van Cuyk S, Deshpande A, Hollander A, Duval N, Ticknor L, Layshock J, Gallegos-Graves L, Omberg KM.

Appl Environ Microbiol. 2011 Nov;77(22):7954-61. doi: 10.1128/AEM.05207-11. Epub 2011 Sep 16.


Molecular characterization of the AdeI mutant of Chinese hamster ovary cells: a cellular model of adenylosuccinate lyase deficiency.

Vliet LK, Wilkinson TG 2nd, Duval N, Vacano G, Graham C, Zikánová M, Skopova V, Baresova V, Hnízda A, Kmoch S, Patterson D.

Mol Genet Metab. 2011 Jan;102(1):61-8. doi: 10.1016/j.ymgme.2010.08.022. Epub 2010 Sep 6.

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