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Items: 20


Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells.

Janus P, Toma-Jonik A, Vydra N, Mrowiec K, Korfanty J, Chadalski M, Widłak P, Dudek K, Paszek A, Rusin M, Polańska J, Widłak W.

Cell Death Differ. 2020 Jan 29. doi: 10.1038/s41418-020-0501-8. [Epub ahead of print]


PHLDA1 Does Not Contribute Directly to Heat Shock-Induced Apoptosis of Spermatocytes.

Janus P, Mrowiec K, Vydra N, Widłak P, Toma-Jonik A, Korfanty J, Smolarczyk R, Widłak W.

Int J Mol Sci. 2019 Dec 30;21(1). pii: E267. doi: 10.3390/ijms21010267.


17β-Estradiol Activates HSF1 via MAPK Signaling in ERα-Positive Breast Cancer Cells.

Vydra N, Janus P, Toma-Jonik A, Stokowy T, Mrowiec K, Korfanty J, Długajczyk A, Wojtaś B, Gielniewski B, Widłak W.

Cancers (Basel). 2019 Oct 11;11(10). pii: E1533. doi: 10.3390/cancers11101533.


Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment.

Sojka DR, Gogler-Pigłowska A, Vydra N, Cortez AJ, Filipczak PT, Krawczyk Z, Scieglinska D.

Sci Rep. 2019 Oct 7;9(1):14394. doi: 10.1038/s41598-019-50840-7.


Interplay between HSF1 and p53 signaling pathways in cancer initiation and progression: non-oncogene and oncogene addiction.

Toma-Jonik A, Vydra N, Janus P, Widłak W.

Cell Oncol (Dordr). 2019 Oct;42(5):579-589. doi: 10.1007/s13402-019-00452-0. Epub 2019 Jun 10. Review.


SPEN protein expression and interactions with chromatin in mouse testicular cells.

Korfanty J, Stokowy T, Chadalski M, Toma-Jonik A, Vydra N, Widłak P, Wojtaś B, Gielniewski B, Widlak W.

Reproduction. 2018 Sep;156(3):195-206. doi: 10.1530/REP-18-0046. Epub 2018 Jun 7.


The Role of Heat Shock Factors in Mammalian Spermatogenesis.

Widlak W, Vydra N.

Adv Anat Embryol Cell Biol. 2017;222:45-65. doi: 10.1007/978-3-319-51409-3_3. Review.


Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes.

Korfanty J, Stokowy T, Widlak P, Gogler-Piglowska A, Handschuh L, Podkowiński J, Vydra N, Naumowicz A, Toma-Jonik A, Widlak W.

Int J Biochem Cell Biol. 2014 Dec;57:76-83. doi: 10.1016/j.biocel.2014.10.006. Epub 2014 Oct 19.


Active heat shock transcription factor 1 supports migration of the melanoma cells via vinculin down-regulation.

Toma-Jonik A, Widlak W, Korfanty J, Cichon T, Smolarczyk R, Gogler-Piglowska A, Widlak P, Vydra N.

Cell Signal. 2015 Feb;27(2):394-401. doi: 10.1016/j.cellsig.2014.11.029. Epub 2014 Nov 27.


Overlapping dose responses of spermatogenic and extragonadal testosterone actions jeopardize the principle of hormonal male contraception.

Oduwole OO, Vydra N, Wood NE, Samanta L, Owen L, Keevil B, Donaldson M, Naresh K, Huhtaniemi IT.

FASEB J. 2014 Jun;28(6):2566-76. doi: 10.1096/fj.13-249219. Epub 2014 Mar 5.


Pleiotropic role of HSF1 in neoplastic transformation.

Vydra N, Toma A, Widlak W.

Curr Cancer Drug Targets. 2014;14(2):144-55. Review.


Overexpression of Heat Shock Transcription Factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel.

Vydra N, Toma A, Glowala-Kosinska M, Gogler-Piglowska A, Widlak W.

BMC Cancer. 2013 Oct 29;13:504. doi: 10.1186/1471-2407-13-504.


Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia.

Kus-Liśkiewicz M, Polańska J, Korfanty J, Olbryt M, Vydra N, Toma A, Widłak W.

BMC Genomics. 2013 Jul 8;14:456. doi: 10.1186/1471-2164-14-456.


Identification of a new mouse sperm acrosome-associated protein.

Korfanty J, Toma A, Wojtas A, Rusin A, Vydra N, Widlak W.

Reproduction. 2012 Jun;143(6):749-57. doi: 10.1530/REP-11-0270. Epub 2012 Apr 11.


Liposome-based DNA carriers may induce cellular stress response and change gene expression pattern in transfected cells.

Fiszer-Kierzkowska A, Vydra N, Wysocka-Wycisk A, Kronekova Z, Jarząb M, Lisowska KM, Krawczyk Z.

BMC Mol Biol. 2011 Jun 10;12:27. doi: 10.1186/1471-2199-12-27.


The expression pattern of the 70-kDa heat shock protein Hspa2 in mouse tissues.

Vydra N, Winiarski B, Rak-Raszewska A, Piglowski W, Mazurek A, Scieglinska D, Widlak W.

Histochem Cell Biol. 2009 Sep;132(3):319-30. doi: 10.1007/s00418-009-0605-1. Epub 2009 May 22.


Heat shock transcription factor 1 down-regulates spermatocyte-specific 70 kDa heat shock protein expression prior to the induction of apoptosis in mouse testes.

Widlak W, Vydra N, Malusecka E, Dudaladava V, Winiarski B, Scieglińska D, Widlak P.

Genes Cells. 2007 Apr;12(4):487-99.


The GC-box is critical for high level expression of the testis-specific Hsp70.2/Hst70 gene.

Widłak W, Vydra N, Dudaladava V, Scieglińska D, Winiarski B, Krawczyk Z.

Acta Biochim Pol. 2007;54(1):107-12. Epub 2007 Feb 20.


Inducible 70 kDa heat shock protein does not protect spermatogenic cells from damage induced by cryptorchidism.

Widlak W, Winiarski B, Krawczyk A, Vydra N, Malusecka E, Krawczyk Z.

Int J Androl. 2007 Apr;30(2):80-7. Epub 2007 Oct 3.


In vivo electroporation of the testis versus transgenic mice model in functional studies of spermatocyte-specific hst70 gene promoter: A comparative study.

Widłak W, Scieglińska D, Vydra N, Małusecka E, Krawczyk Z.

Mol Reprod Dev. 2003 Aug;65(4):382-8.


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