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Items: 5

1.

Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.

Semenova MN, Demchuk DV, Tsyganov DV, Chernysheva NB, Samet AV, Silyanova EA, Kislyi VP, Maksimenko AS, Varakutin AE, Konyushkin LD, Raihstat MM, Kiselyov AS, Semenov VV.

ACS Comb Sci. 2018 Dec 10;20(12):700-721. doi: 10.1021/acscombsci.8b00113. Epub 2018 Nov 29.

PMID:
30452225
2.

Regioselective synthesis of 3,4-diaryl-5-unsubstituted isoxazoles, analogues of natural cytostatic combretastatin A4.

Chernysheva NB, Maksimenko AS, Andreyanov FA, Kislyi VP, Strelenko YA, Khrustalev VN, Semenova MN, Semenov VV.

Eur J Med Chem. 2018 Feb 25;146:511-518. doi: 10.1016/j.ejmech.2018.01.070. Epub 2018 Jan 31.

PMID:
29407976
3.

Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.

Demchuk DV, Samet AV, Chernysheva NB, Ushkarov VI, Stashina GA, Konyushkin LD, Raihstat MM, Firgang SI, Philchenkov AA, Zavelevich MP, Kuiava LM, Chekhun VF, Blokhin DY, Kiselyov AS, Semenova MN, Semenov VV.

Bioorg Med Chem. 2014 Jan 15;22(2):738-55. doi: 10.1016/j.bmc.2013.12.015. Epub 2013 Dec 12.

PMID:
24387982
4.

Synthesis and comparative evaluation of 4-oxa- and 4-aza-podophyllotoxins as antiproliferative microtubule destabilizing agents.

Chernysheva NB, Tsyganov DV, Philchenkov AA, Zavelevich MP, Kiselyov AS, Semenov RV, Semenova MN, Semenov VV.

Bioorg Med Chem Lett. 2012 Apr 1;22(7):2590-3. doi: 10.1016/j.bmcl.2012.01.128. Epub 2012 Feb 9.

PMID:
22370267
5.

Synthesis of antimitotic polyalkoxyphenyl derivatives of combretastatin using plant allylpolyalkoxybenzenes.

Semenov VV, Kiselyov AS, Titov IY, Sagamanova IK, Ikizalp NN, Chernysheva NB, Tsyganov DV, Konyushkin LD, Firgang SI, Semenov RV, Karmanova IB, Raihstat MM, Semenova MN.

J Nat Prod. 2010 Nov 29;73(11):1796-802. doi: 10.1021/np1004278. Epub 2010 Nov 4. No abstract available.

PMID:
21049975

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