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Items: 1 to 20 of 52

1.

Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential.

Markov AV, Babich VO, Popadyuk II, Salomatina OV, Logashenko EB, Salakhutdinov NF, Zenkova MA.

Molecules. 2019 Jul 21;24(14). pii: E2644. doi: 10.3390/molecules24142644.

2.

Antimicrobial Activity of Substituted Benzopentathiepin-6-amines.

Khomenko TM, Korchagina DV, Baev DS, Vassiliev PM, Volcho KP, Salakhutdinov NF.

J Antibiot (Tokyo). 2019 Aug;72(8):590-599. doi: 10.1038/s41429-019-0191-y. Epub 2019 May 22.

PMID:
31118480
3.

Single-stage synthesis of heterocyclic alkaloid-like compounds from (+)-camphoric acid and their antiviral activity.

Chernyshov VV, Yarovaya OI, Fadeev DS, Gatilov YV, Esaulkova YL, Muryleva AS, Sinegubova KO, Zarubaev VV, Salakhutdinov NF.

Mol Divers. 2019 Feb 28. doi: 10.1007/s11030-019-09932-9. [Epub ahead of print]

PMID:
30820742
4.

Synthesis of d-(+)-camphor-based N-acylhydrazones and their antiviral activity.

Kovaleva KS, Zubkov FI, Bormotov NI, Novikov RA, Dorovatovskii PV, Khrustalev VN, Gatilov YV, Zarubaev VV, Yarovaya OI, Shishkina LN, Salakhutdinov NF.

Medchemcomm. 2018 Oct 26;9(12):2072-2082. doi: 10.1039/c8md00442k. eCollection 2018 Dec 1.

PMID:
30746065
5.

Mechanism of action of an old antibiotic revisited: Role of calcium ions in protonophoric activity of usnic acid.

Antonenko YN, Khailova LS, Rokitskaya TI, Nosikova ES, Nazarov PA, Luzina OA, Salakhutdinov NF, Kotova EA.

Biochim Biophys Acta Bioenerg. 2019 Apr 1;1860(4):310-316. doi: 10.1016/j.bbabio.2019.01.005. Epub 2019 Jan 30.

PMID:
30710552
6.

Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments.

Mozhaitsev ES, Zakharenko AL, Suslov EV, Korchagina DV, Zakharova OD, Vasil'eva IA, Chepanova AA, Black E, Patel J, Chand R, Reynisson J, Leung IKH, Volcho KP, Salakhutdinov NF, Lavrik OI.

Anticancer Agents Med Chem. 2019;19(4):463-472. doi: 10.2174/1871520619666181207094243.

PMID:
30523770
7.

Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors.

Sokolova AS, Yarovaya OI, Bormotov NI, Shishkina LN, Salakhutdinov NF.

Medchemcomm. 2018 Sep 19;9(10):1746-1753. doi: 10.1039/c8md00347e. eCollection 2018 Oct 1.

PMID:
30429979
8.

A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold.

Li-Zhulanov NS, Zakharenko AL, Chepanova AA, Patel J, Zafar A, Volcho KP, Salakhutdinov NF, Reynisson J, Leung IKH, Lavrik OI.

Molecules. 2018 Sep 26;23(10). pii: E2468. doi: 10.3390/molecules23102468.

9.

Untargeted search and identification of metabolites of antiviral agent camphecene in rat urine by liquid chromatography and mass spectrometry and studying their distribution in organs following peroral administration of the compound.

Rogachev AD, Yarovaya OI, Fatianova AV, Lavrinenko VA, Amosov EV, Zarubaev VV, Pokrovsky AG, Salakhutdinov NF.

J Pharm Biomed Anal. 2018 Nov 30;161:383-392. doi: 10.1016/j.jpba.2018.09.003. Epub 2018 Sep 5.

PMID:
30205302
10.

Neuroregeneration in Parkinson's Disease: From Proteins to Small Molecules.

Sidorova YA, Volcho KP, Salakhutdinov NF.

Curr Neuropharmacol. 2019;17(3):268-287. doi: 10.2174/1570159X16666180905094123. Review.

PMID:
30182859
11.

Selection of influenza virus resistant to the novel camphor-based antiviral camphecene results in loss of pathogenicity.

Zarubaev VV, Pushkina EA, Borisevich SS, Galochkina AV, Garshinina AV, Shtro AA, Egorova AA, Sokolova AS, Khursan SL, Yarovaya OI, Salakhutdinov NF.

Virology. 2018 Nov;524:69-77. doi: 10.1016/j.virol.2018.08.011. Epub 2018 Aug 27.

PMID:
30165308
12.

Discovery of a New Class of Inhibitors of Vaccinia Virus Based on (-)-Borneol from Abies sibirica and (+)-Camphor.

Sokolova AS, Yarovaya OI, Bormotov NI, Shishkina LN, Salakhutdinov NF.

Chem Biodivers. 2018 Sep;15(9):e1800153. doi: 10.1002/cbdv.201800153. Epub 2018 Aug 9.

PMID:
29956885
13.

Usnic acid and its derivatives for pharmaceutical use: a patent review (2000-2017).

Luzina OA, Salakhutdinov NF.

Expert Opin Ther Pat. 2018 Jun;28(6):477-491. doi: 10.1080/13543776.2018.1472239. Epub 2018 May 9. Review.

PMID:
29718734
14.

Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses.

Ilyina IV, Zarubaev VV, Lavrentieva IN, Shtro AA, Esaulkova IL, Korchagina DV, Borisevich SS, Volcho KP, Salakhutdinov NF.

Bioorg Med Chem Lett. 2018 Jun 15;28(11):2061-2067. doi: 10.1016/j.bmcl.2018.04.057. Epub 2018 Apr 24.

PMID:
29716780
15.

Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.

Salomatina OV, Popadyuk II, Zakharenko AL, Zakharova OD, Fadeev DS, Komarova NI, Reynisson J, Arabshahi HJ, Chand R, Volcho KP, Salakhutdinov NF, Lavrik OI.

Molecules. 2018 Mar 17;23(3). pii: E679. doi: 10.3390/molecules23030679.

16.

Globular chitosan prolongs the effective duration time and decreases the acute toxicity of botulinum neurotoxin after intramuscular injection in rats.

Sergeevichev DS, Krasilnikova AA, Strelnikov AG, Fomenko VV, Salakhutdinov NF, Romanov AB, Karaskov AM, Pokushalov EA, Steinberg JS.

Toxicon. 2018 Mar 1;143:90-95. doi: 10.1016/j.toxicon.2018.01.013. Epub 2018 Jan 31.

PMID:
29371111
17.

Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors.

Ponomarev KY, Suslov EV, Zakharenko AL, Zakharova OD, Rogachev AD, Korchagina DV, Zafar A, Reynisson J, Nefedov AA, Volcho KP, Salakhutdinov NF, Lavrik OI.

Bioorg Chem. 2018 Feb;76:392-399. doi: 10.1016/j.bioorg.2017.12.005. Epub 2017 Dec 9.

PMID:
29248742
18.

Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation.

Markov AV, Sen'kova AV, Warszycki D, Salomatina OV, Salakhutdinov NF, Zenkova MA, Logashenko EB.

Sci Rep. 2017 Oct 25;7(1):13968. doi: 10.1038/s41598-017-14029-0.

19.

Effects of fluorine-containing usnic acid and fungus Beauveria bassiana on the survival and immune-physiological reactions of Colorado potato beetle larvae.

Kryukov VY, Tomilova OG, Luzina OA, Yaroslavtseva ON, Akhanaev YB, Tyurin MV, Duisembekov BA, Salakhutdinov NF, Glupov VV.

Pest Manag Sci. 2018 Mar;74(3):598-606. doi: 10.1002/ps.4741. Epub 2017 Nov 2.

PMID:
28945317
20.

Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position.

Popadyuk II, Markov AV, Morozova EA, Babich VO, Salomatina OV, Logashenko EB, Zenkova MA, Tolstikova TG, Salakhutdinov NF.

Steroids. 2017 Nov;127:1-12. doi: 10.1016/j.steroids.2017.08.016. Epub 2017 Sep 5.

PMID:
28887170

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