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Mutagenic potential of 8-oxo-7,8-dihydroguanine (8-oxoG) is influenced by nearby clustered lesions.
Shikazono N, Akamatsu K.
Mutat Res. 2018 Jul;810:6-12. doi: 10.1016/j.mrfmmm.2018.05.001. Epub 2018 May 26.
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New method for estimating clustering of DNA lesions induced by physical/chemical mutagens using fluorescence anisotropy.
Akamatsu K, Shikazono N, Saito T.
Anal Biochem. 2017 Nov 1;536:78-89. doi: 10.1016/j.ab.2017.08.007. Epub 2017 Aug 18.
Radiation-induced clustered DNA lesions: Repair and mutagenesis.
Sage E, Shikazono N.
Free Radic Biol Med. 2017 Jun;107:125-135. doi: 10.1016/j.freeradbiomed.2016.12.008. Epub 2016 Dec 8. Review.
Efficiency of radiation-induced base lesion excision and the order of enzymatic treatment.
Shiraishi I, Shikazono N, Suzuki M, Fujii K, Yokoya A.
Int J Radiat Biol. 2017 Mar;93(3):295-302. doi: 10.1080/09553002.2017.1239849. Epub 2016 Nov 2.
A polymerization-based method to construct a plasmid containing clustered DNA damage and a mismatch.
Takahashi M, Akamatsu K, Shikazono N.
Anal Biochem. 2016 Oct 1;510:129-135. doi: 10.1016/j.ab.2016.07.007. Epub 2016 Jul 21.
Localization estimation of ionizing radiation-induced abasic sites in DNA in the solid state using fluorescence resonance energy transfer.
Radiat Res. 2015 Jan;183(1):105-13. doi: 10.1667/RR13780.1. Epub 2015 Jan 7.
Chemical repair activity of free radical scavenger edaravone: reduction reactions with dGMP hydroxyl radical adducts and suppression of base lesions and AP sites on irradiated plasmid DNA.
Hata K, Urushibara A, Yamashita S, Lin M, Muroya Y, Shikazono N, Yokoya A, Fu H, Katsumura Y.
J Radiat Res. 2015 Jan;56(1):59-66. doi: 10.1093/jrr/rru079. Epub 2014 Sep 11.
Significance of DNA polymerase I in in vivo processing of clustered DNA damage.
Shikazono N, Akamatsu K, Takahashi M, Noguchi M, Urushibara A, O'Neill P, Yokoya A.
Mutat Res. 2013 Sep;749(1-2):9-15. doi: 10.1016/j.mrfmmm.2013.07.010. Epub 2013 Aug 17. Erratum in: Mutat Res. 2013 Nov-Dec;751-752:55.
Chemical repair of base lesions, AP-sites, and strand breaks on plasmid DNA in dilute aqueous solution by ascorbic acid.
Hata K, Urushibara A, Yamashita S, Shikazono N, Yokoya A, Katsumura Y.
Biochem Biophys Res Commun. 2013 May 3;434(2):341-5. doi: 10.1016/j.bbrc.2013.03.075. Epub 2013 Apr 6.
A methodology for estimating localization of apurinic/apyrimidinic sites in DNA using fluorescence resonance energy transfer.
Akamatsu K, Shikazono N.
Anal Biochem. 2013 Feb 15;433(2):171-80. doi: 10.1016/j.ab.2012.10.004. Epub 2012 Oct 12.
The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions.
Noguchi M, Urushibara A, Yokoya A, O'Neill P, Shikazono N.
Mutat Res. 2012 Apr 1;732(1-2):34-42. doi: 10.1016/j.mrfmmm.2011.12.009. Epub 2012 Jan 13.
Yield of single- and double-strand breaks and nucleobase lesions in fully hydrated plasmid DNA films irradiated with high-LET charged particles.
Ushigome T, Shikazono N, Fujii K, Watanabe R, Suzuki M, Tsuruoka C, Tauchi H, Yokoya A.
Radiat Res. 2012 May;177(5):614-27. Epub 2011 Dec 29.
A novel technique using DNA denaturation to detect multiply induced single-strand breaks in a hydrated plasmid DNA molecule by X-ray and 4He2+ ion irradiation.
Yokoya A, Shikazono N, Fujii K, Noguchi M, Urushibara A.
Radiat Prot Dosimetry. 2011 Feb;143(2-4):219-25. doi: 10.1093/rpd/ncq540. Epub 2010 Dec 24.
Protective effects of silybin and analogues against X-ray radiation-induced damage.
Fu H, Lin M, Katsumura Y, Yokoya A, Hata K, Muroya Y, Fujii K, Shikazono N.
Acta Biochim Biophys Sin (Shanghai). 2010 Jul;42(7):489-95. doi: 10.1093/abbs/gmq045. Epub 2010 Jun 9.
Studies on biological effects of ion beams on lethality, molecular nature of mutation, mutation rate, and spectrum of mutation phenotype for mutation breeding in higher plants.
Tanaka A, Shikazono N, Hase Y.
J Radiat Res. 2010;51(3):223-33.
Nucleobase lesions and strand breaks in dry DNA thin film selectively induced by monochromatic soft X-rays.
Fujii K, Shikazono N, Yokoya A.
J Phys Chem B. 2009 Dec 10;113(49):16007-15. doi: 10.1021/jp9062737.
Free radical scavenging reactions and antioxidant activities of silybin: mechanistic aspects and pulse radiolytic studies.
Fu H, Lin M, Muroya Y, Hata K, Katsumura Y, Yokoya A, Shikazono N, Hatano Y.
Free Radic Res. 2009 Sep;43(9):887-97. doi: 10.1080/10715760903136996.
A UVB-hypersensitive mutant in Arabidopsis thaliana is defective in the DNA damage response.
Sakamoto AN, Lan VT, Puripunyavanich V, Hase Y, Yokota Y, Shikazono N, Nakagawa M, Narumi I, Tanaka A.
Plant J. 2009 Nov;60(3):509-17. doi: 10.1111/j.1365-313X.2009.03974.x. Epub 2009 Jul 8.
Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.
Shikazono N, O'Neill P.
Mutat Res. 2009 Oct 2;669(1-2):162-8. doi: 10.1016/j.mrfmmm.2009.06.004. Epub 2009 Jun 18.
Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.
Bellon S, Shikazono N, Cunniffe S, Lomax M, O'Neill P.
Nucleic Acids Res. 2009 Jul;37(13):4430-40. doi: 10.1093/nar/gkp422. Epub 2009 May 25.
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