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Items: 1 to 20 of 54


Synthesis and In Vitro Evaluation of Novel Liver X Receptor Agonists Based on Naphthoquinone Derivatives.

Nishioka T, Endo-Umeda K, Ito Y, Shimoda A, Takeuchi A, Tode C, Hirota Y, Osakabe N, Makishima M, Suhara Y.

Molecules. 2019 Nov 26;24(23). pii: E4316. doi: 10.3390/molecules24234316.


Elucidation of the Interaction between Flavan-3-ols and Bovine Serum Albumin and Its Effect on Their In-Vitro Cytotoxicity.

Fujii Y, Suhara Y, Sukikara Y, Teshima T, Hirota Y, Yoshimura K, Osakabe N.

Molecules. 2019 Oct 11;24(20). pii: E3667. doi: 10.3390/molecules24203667.


Corticotropin-releasing hormone is significantly upregulated in the mouse paraventricular nucleus following a single oral dose of cinnamtannin A2 as an (-)-epicatechin tetramer.

Fujii Y, Suzuki K, Adachi T, Taira S, Osakabe N.

J Clin Biochem Nutr. 2019 Jul;65(1):29-33. doi: 10.3164/jcbn.19-19. Epub 2019 Jun 7.


Electrochemical determination with a long-length carbon nanotube electrode of quercetin glucosides in onion, apple peel, and tartary buckwheat.

Takahashi S, Muguruma H, Osakabe N, Inoue H, Ohsawa T.

Food Chem. 2019 Dec 1;300:125189. doi: 10.1016/j.foodchem.2019.125189. Epub 2019 Jul 16.


Acylated anthocyanins derived from purple carrot (Daucus carota L.) induce elevation of blood flow in rat cremaster arteriole.

Tsutsumi A, Horikoshi Y, Fushimi T, Saito A, Koizumi R, Fujii Y, Hu QQ, Hirota Y, Aizawa K, Osakabe N.

Food Funct. 2019 Mar 20;10(3):1726-1735. doi: 10.1039/c8fo02125b.


Polyphenol Analysis in Black Tea with a Carbon Nanotube Electrode.

Murakami S, Takahashi S, Muguruma H, Osakabe N, Inoue H, Ohsawa T.

Anal Sci. 2019 May 10;35(5):529-534. doi: 10.2116/analsci.18P516. Epub 2019 Jan 4.


Separationless and Adsorptionless Quantification of Individual Catechins in Green Tea with a Carbon Nanotube-Carboxymethylcellulose Electrode.

Muguruma H, Murakami S, Takahashi S, Osakabe N, Inoue H, Ohsawa T.

J Agric Food Chem. 2019 Jan 23;67(3):943-954. doi: 10.1021/acs.jafc.8b05540. Epub 2019 Jan 10.


Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice.

Hirota Y, Nakagawa K, Isomoto K, Sakaki T, Kubodera N, Kamao M, Osakabe N, Suhara Y, Okano T.

PLoS One. 2018 Oct 3;13(10):e0199856. doi: 10.1371/journal.pone.0199856. eCollection 2018.


Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice.

Nakagawa Y, Ishimura K, Oya S, Kamino M, Fujii Y, Nanba F, Toda T, Ishii T, Adachi T, Suhara Y, Osakabe N.

PLoS One. 2018 Jul 30;13(7):e0201203. doi: 10.1371/journal.pone.0201203. eCollection 2018.


Green tea extract and black tea extract differentially influence cecal levels of short-chain fatty acids in rats.

Unno T, Osakabe N.

Food Sci Nutr. 2018 Mar 1;6(4):728-735. doi: 10.1002/fsn3.607. eCollection 2018 Jun.


Single oral administration of flavan 3-ols induces stress responses monitored with stress hormone elevations in the plasma and paraventricular nucleus.

Fujii Y, Suzuki K, Hasegawa Y, Nanba F, Toda T, Adachi T, Taira S, Osakabe N.

Neurosci Lett. 2018 Aug 24;682:106-111. doi: 10.1016/j.neulet.2018.06.015. Epub 2018 Jun 11.


Possible mechanisms of postprandial physiological alterations following flavan 3-ol ingestion.

Osakabe N, Terao J.

Nutr Rev. 2018 Mar 1;76(3):174-186. doi: 10.1093/nutrit/nux070. Review.


Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice.

Ito M, Kudo N, Miyake Y, Imai T, Unno T, Yamashita Y, Hirota Y, Ashida H, Osakabe N.

Exp Gerontol. 2017 Nov;98:120-123. doi: 10.1016/j.exger.2017.07.010. Epub 2017 Aug 12.


Synthesis of Novel Synthetic Vitamin K Analogues Prepared by Introduction of a Heteroatom and a Phenyl Group That Induce Highly Selective Neuronal Differentiation of Neuronal Progenitor Cells.

Kimura K, Hirota Y, Kuwahara S, Takeuchi A, Tode C, Wada A, Osakabe N, Suhara Y.

J Med Chem. 2017 Mar 23;60(6):2591-2596. doi: 10.1021/acs.jmedchem.6b01717. Epub 2017 Mar 3.


Substitution at the C-3 Position of Catechins Has an Influence on the Binding Affinities against Serum Albumin.

Ikeda M, Ueda-Wakagi M, Hayashibara K, Kitano R, Kawase M, Kaihatsu K, Kato N, Suhara Y, Osakabe N, Ashida H.

Molecules. 2017 Feb 18;22(2). pii: E314. doi: 10.3390/molecules22020314.


Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo.

Adachi T, Kakuta S, Aihara Y, Kamiya T, Watanabe Y, Osakabe N, Hazato N, Miyawaki A, Yoshikawa S, Usami T, Karasuyama H, Kimoto-Nira H, Hirayama K, Tsuji NM.

Front Immunol. 2016 Dec 16;7:601. doi: 10.3389/fimmu.2016.00601. eCollection 2016.


Onset of a hypotensive effect following ingestion of flavan 3-ols involved in the activation of adrenergic receptors.

Saito A, Inagawa K, Ebe R, Fukase S, Horikoshi Y, Shibata M, Osakabe N.

Free Radic Biol Med. 2016 Oct;99:584-592. doi: 10.1016/j.freeradbiomed.2016.09.008. Epub 2016 Sep 9.


Catecholamines Facilitate Fuel Expenditure and Protect Against Obesity via a Novel Network of the Gut-Brain Axis in Transcription Factor Skn-1-deficient Mice.

Ushiama S, Ishimaru Y, Narukawa M, Yoshioka M, Kozuka C, Watanabe N, Tsunoda M, Osakabe N, Asakura T, Masuzaki H, Abe K.

EBioMedicine. 2016 Jun;8:60-71. doi: 10.1016/j.ebiom.2016.04.031. Epub 2016 Apr 30.


The impact of theaflavins on systemic-and microcirculation alterations: The murine and randomized feasibility trials.

Saito A, Nakazato R, Suhara Y, Shibata M, Fukui T, Ishii T, Asanuma T, Mochizuki K, Nakayama T, Osakabe N.

J Nutr Biochem. 2016 Jun;32:107-14. doi: 10.1016/j.jnutbio.2016.01.012. Epub 2016 Mar 18.


A single oral dose of flavan-3-ols enhances energy expenditure by sympathetic nerve stimulation in mice.

Kamio N, Suzuki T, Watanabe Y, Suhara Y, Osakabe N.

Free Radic Biol Med. 2016 Feb;91:256-63. doi: 10.1016/j.freeradbiomed.2015.12.030. Epub 2015 Dec 29.


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