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Items: 1 to 20 of 100

1.

NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model.

Fukatsu H, Koide N, Tada-Oikawa S, Izuoka K, Ikegami A, Ichihara S, Ukaji T, Morita N, Naiki Y, Komatsu T, Umezawa K.

Mol Med Rep. 2018 Dec;18(6):5279-5285. doi: 10.3892/mmr.2018.9533. Epub 2018 Oct 3.

PMID:
30320338
2.

Sendai virus C protein limits NO production in infected RAW264.7 macrophages.

Odkhuu E, Komatsu T, Koide N, Naiki Y, Takeuchi K, Tanaka Y, Tsolmongyn B, Jambalganiin U, Morita N, Yoshida T, Gotoh B, Yokochi T.

Innate Immun. 2018 Oct;24(7):430-438. doi: 10.1177/1753425918796619. Epub 2018 Sep 6.

PMID:
30189760
3.

Sendai Virus V Protein Inhibits the Secretion of Interleukin-1β by Preventing NLRP3 Inflammasome Assembly.

Komatsu T, Tanaka Y, Kitagawa Y, Koide N, Naiki Y, Morita N, Gotoh B, Yokochi T.

J Virol. 2018 Sep 12;92(19). pii: e00842-18. doi: 10.1128/JVI.00842-18. Print 2018 Oct 1.

PMID:
30021903
4.

Inhibition of Late and Early Phases of Cancer Metastasis by the NF-κB Inhibitor DHMEQ Derived from Microbial Bioactive Metabolite Epoxyquinomicin: A Review.

Lin Y, Ukaji T, Koide N, Umezawa K.

Int J Mol Sci. 2018 Mar 3;19(3). pii: E729. doi: 10.3390/ijms19030729. Review.

5.

Therapeutic activity of plant-derived alkaloid conophylline on metabolic syndrome and neurodegenerative disease models.

Umezawa K, Kojima I, Simizu S, Lin Y, Fukatsu H, Koide N, Nakade Y, Yoneda M.

Hum Cell. 2018 Apr;31(2):95-101. doi: 10.1007/s13577-017-0196-4. Epub 2017 Dec 16. Review.

PMID:
29249016
6.

Rational design, synthesis and in vitro evaluation of novel exo-methylene butyrolactone salicyloylamide as NF-κB inhibitor.

Sidthipong K, Ma J, Yu WL, Wang YF, Kobayashi S, Kishino S, Koide N, Yokochi T, Kato K, Okada S, Umezawa K.

Bioorg Med Chem Lett. 2017 Feb 1;27(3):562-566. doi: 10.1016/j.bmcl.2016.12.017. Epub 2016 Dec 8.

PMID:
28003138
7.

A Wnt Pathway Activator Induces Apoptosis and Cell Death in Mouse Monocytic Leukemia Cells.

Kato Y, Naiki Y, Komatsu T, Takahashi K, Nakamura J, Koide N.

Oncol Res. 2017 Apr 14;25(4):479-483. doi: 10.3727/096504016X14721731148893. Epub 2016 Sep 12.

PMID:
27623760
8.

GSK2656157, a PERK inhibitor, reduced LPS-induced IL-1β production through inhibiting Caspase 1 activation in macrophage-like J774.1 cells.

Ando T, Komatsu T, Naiki Y, Takahashi K, Yokochi T, Watanabe D, Koide N.

Immunopharmacol Immunotoxicol. 2016 Aug;38(4):298-302. doi: 10.1080/08923973.2016.1192191. Epub 2016 Jun 16.

PMID:
27251848
9.

Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS.

Ando T, Komatsu T, Naiki Y, Yokochi T, Watanabe D, Koide N.

Biomed Pharmacother. 2015 Dec;76:1-5. doi: 10.1016/j.biopha.2015.10.019. Epub 2015 Nov 9.

PMID:
26653542
10.

TGF-β1 inhibits the production of IFN in response to CpG DNA via ubiquitination of TNF receptor-associated factor (TRAF) 6.

Naiki Y, Komatsu T, Koide N, Dagvadorj J, Yoshida T, Arditi M, Yokochi T.

Innate Immun. 2015 Oct;21(7):770-7. doi: 10.1177/1753425915596844. Epub 2015 Jul 29.

PMID:
26224488
11.

Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production.

Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Watarai A, Kondo M, Kato K, Nakamura J, Yokochi T.

Int Immunopharmacol. 2015 May;26(1):97-102. doi: 10.1016/j.intimp.2015.03.015. Epub 2015 Mar 24.

PMID:
25817178
12.

Inhibition of RANKL- and LPS-induced osteoclast differentiations by novel NF-κB inhibitor DTCM-glutarimide.

Koide N, Kaneda A, Yokochi T, Umezawa K.

Int Immunopharmacol. 2015 Mar;25(1):162-8. doi: 10.1016/j.intimp.2015.01.004. Epub 2015 Jan 21.

PMID:
25617668
13.

Poly I:C enhances production of nitric oxide in response to interferon-γ via upregulation of interferon regulatory factor 7 in vascular endothelial cells.

Mori D, Koide N, Tsolmongyn B, Nagata H, Sano T, Nonami T, Yokochi T.

Microvasc Res. 2015 Mar;98:68-73. doi: 10.1016/j.mvr.2015.01.003. Epub 2015 Jan 9.

PMID:
25582076
14.

Sendai virus C protein inhibits lipopolysaccharide-induced nitric oxide production through impairing interferon-β signaling.

Odkhuu E, Komatsu T, Naiki Y, Koide N, Yokochi T.

Int Immunopharmacol. 2014 Nov;23(1):267-72. doi: 10.1016/j.intimp.2014.09.012. Epub 2014 Sep 19.

PMID:
25242386
15.

Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B.

Odkhuu E, Mendjargal A, Koide N, Naiki Y, Komatsu T, Yokochi T.

Immunobiology. 2015 Jan;220(1):136-41. doi: 10.1016/j.imbio.2014.08.010. Epub 2014 Aug 14.

PMID:
25172547
16.

Spironolactone inhibits production of proinflammatory mediators in response to lipopolysaccharide via inactivation of nuclear factor-κB.

Kato Y, Kamiya H, Koide N, Odkhuu E, Komatsu T, Dagvadorj J, Watarai A, Kondo M, Kato K, Nakamura J, Yokochi T.

Immunopharmacol Immunotoxicol. 2014 Jun;36(3):237-41. doi: 10.3109/08923973.2014.921690.

PMID:
24852317
17.

Inhibition of receptor activator of nuclear factor-κB ligand- or lipopolysaccharide-induced osteoclast formation by conophylline through downregulation of CREB.

Koide N, Kondo Y, Odkhuu E, Ulziisaikhan J, Ukaji T, Yokochi T, Umezawa K.

Immunol Lett. 2014 Sep;161(1):31-7. doi: 10.1016/j.imlet.2014.04.006. Epub 2014 May 2.

PMID:
24792671
18.

A novel mechanism for inhibition of lipopolysaccharide-induced proinflammatory cytokine production by valproic acid.

Jambalganiin U, Tsolmongyn B, Koide N, Odkhuu E, Naiki Y, Komatsu T, Yoshida T, Yokochi T.

Int Immunopharmacol. 2014 May;20(1):181-7. doi: 10.1016/j.intimp.2014.02.032. Epub 2014 Mar 12.

PMID:
24631367
19.

Involvement of redox balance in in vitro osteoclast formation of RAW 264.7 macrophage cells in response to LPS.

Odkhuu E, Koide N, Tsolmongyn B, Jambalganiin U, Naiki Y, Komatsu T, Yoshida T, Yokochi T.

Innate Immun. 2015 Feb;21(2):194-202. doi: 10.1177/1753425914524242. Epub 2014 Mar 4.

PMID:
24595208
20.

Lipopolysaccharide impairs insulin sensitivity via activation of phosphoinositide 3-kinase in adipocytes.

Wakayama S, Haque A, Koide N, Kato Y, Odkhuu E, Bilegtsaikhan T, Naiki Y, Komatsu T, Yoshida T, Yokochi T.

Immunopharmacol Immunotoxicol. 2014 Apr;36(2):145-9. doi: 10.3109/08923973.2014.887096. Epub 2014 Feb 10.

PMID:
24506665

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