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Items: 1 to 20 of 25

1.

Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer.

Taverna JA, Hung CN, DeArmond DT, Chen M, Lin CL, Osmulski PA, Gaczynska ME, Wang CM, Lucio ND, Chou CW, Chen CL, Nazarullah A, Lampkin SR, Qiu L, Bearss DJ, Warner S, Whatcott CJ, Mouritsen L, Wade M, Weitman S, Mesa RA, Kirma NB, Chao WT, Huang TH.

Cancer Res. 2020 Apr 1;80(7):1551-1563. doi: 10.1158/0008-5472.CAN-19-3183. Epub 2020 Jan 28.

PMID:
31992541
2.

Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer.

Liu YL, Horning AM, Lieberman B, Kim M, Lin CK, Hung CN, Chou CW, Wang CM, Lin CL, Kirma NB, Liss MA, Vasisht R, Perillo EP, Blocher K, Horng H, Taverna JA, Ruan J, Yankeelov TE, Dunn AK, Huang TH, Yeh HC, Chen CL.

Cancers (Basel). 2019 Dec 1;11(12). pii: E1910. doi: 10.3390/cancers11121910.

3.

Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer.

Polusani SR, Huang YW, Huang G, Chen CW, Wang CM, Lin LL, Osmulski P, Lucio ND, Liu L, Hsu YT, Zhou Y, Lin CL, Aguilera-Barrantes I, Valente PT, Kost ER, Chen CL, Shim EY, Lee SE, Ruan J, Gaczynska ME, Yan P, Goodfellow PJ, Mutch DG, Jin VX, Nicholson BJ, Huang TH, Kirma NB.

Cancer Res. 2019 Jan 1;79(1):196-208. doi: 10.1158/0008-5472.CAN-18-1615. Epub 2018 Nov 2.

4.

Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response.

Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, Jin VX, Chen CL, Huang TH.

Cancer Res. 2018 Feb 15;78(4):853-864. doi: 10.1158/0008-5472.CAN-17-1924. Epub 2017 Dec 12.

5.

EGFR-Dependent Regulated Intramembrane Proteolysis of EpCAM-Response.

Hsu YT, Osmulski P, Wang Y, Huang YW, Liu L, Ruan J, Jin VX, Kirma NB, Gaczynska ME, Huang TH.

Cancer Res. 2017 Apr 1;77(7):1777. doi: 10.1158/0008-5472.CAN-16-3440. Epub 2017 Mar 22. No abstract available.

6.

EpCAM-Regulated Transcription Exerts Influences on Nanomechanical Properties of Endometrial Cancer Cells That Promote Epithelial-to-Mesenchymal Transition.

Hsu YT, Osmulski P, Wang Y, Huang YW, Liu L, Ruan J, Jin VX, Kirma NB, Gaczynska ME, Huang TH.

Cancer Res. 2016 Nov 1;76(21):6171-6182. Epub 2016 Aug 28. Erratum in: Cancer Res. 2017 Apr 1;77(7):1778.

7.

A novel algorithm for network-based prediction of cancer recurrence.

Ruan J, Jahid MJ, Gu F, Lei C, Huang YW, Hsu YT, Mutch DG, Chen CL, Kirma NB, Huang TH.

Genomics. 2019 Jan;111(1):17-23. doi: 10.1016/j.ygeno.2016.07.005. Epub 2016 Jul 21.

8.

Co-targeting ALK and EGFR parallel signaling in oral squamous cell carcinoma.

Gonzales CB, De La Chapa JJ, Saikumar P, Singha PK, Dybdal-Hargreaves NF, Chavez J, Horning AM, Parra J, Kirma NB.

Oral Oncol. 2016 Aug;59:12-19. doi: 10.1016/j.oraloncology.2016.05.007.

9.

Aromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cells.

Mukhopadhyay KD, Liu Z, Bandyopadhyay A, Kirma NB, Tekmal RR, Wang S, Sun LZ.

PLoS One. 2015 Apr 2;10(4):e0121136. doi: 10.1371/journal.pone.0121136. eCollection 2015.

10.

Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer.

Jadhav RR, Ye Z, Huang RL, Liu J, Hsu PY, Huang YW, Rangel LB, Lai HC, Roa JC, Kirma NB, Huang TH, Jin VX.

Clin Epigenetics. 2015 Feb 24;7:13. doi: 10.1186/s13148-015-0045-9. eCollection 2015.

11.

Effects of a novel proteasome inhibitor BU-32 on multiple myeloma cells.

Roy SS, Kirma NB, Santhamma B, Tekmal RR, Agyin JK.

Cancer Chemother Pharmacol. 2014 Jun;73(6):1263-71. doi: 10.1007/s00280-014-2463-3. Epub 2014 Apr 12.

12.

Vanilloids induce oral cancer apoptosis independent of TRPV1.

Gonzales CB, Kirma NB, De La Chapa JJ, Chen R, Henry MA, Luo S, Hargreaves KM.

Oral Oncol. 2014 May;50(5):437-47. doi: 10.1016/j.oraloncology.2013.12.023. Epub 2014 Jan 14.

13.

Promoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer.

Hsu YT, Gu F, Huang YW, Liu J, Ruan J, Huang RL, Wang CM, Chen CL, Jadhav RR, Lai HC, Mutch DG, Goodfellow PJ, Thompson IM, Kirma NB, Huang TH.

Clin Cancer Res. 2013 Nov 15;19(22):6272-85. doi: 10.1158/1078-0432.CCR-13-1734. Epub 2013 Sep 27.

14.

Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer.

Hsu PY, Hsu HK, Lan X, Juan L, Yan PS, Labanowska J, Heerema N, Hsiao TH, Chiu YC, Chen Y, Liu Y, Li L, Li R, Thompson IM, Nephew KP, Sharp ZD, Kirma NB, Jin VX, Huang TH.

Cancer Cell. 2013 Aug 12;24(2):197-212. doi: 10.1016/j.ccr.2013.07.007.

15.

Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers.

Huang RL, Gu F, Kirma NB, Ruan J, Chen CL, Wang HC, Liao YP, Chang CC, Yu MH, Pilrose JM, Thompson IM, Huang HC, Huang TH, Lai HC, Nephew KP.

Epigenetics. 2013 Jun;8(6):624-34. doi: 10.4161/epi.24816. Epub 2013 May 10.

16.

Epigenetic deregulation of the anaplastic lymphoma kinase gene modulates mesenchymal characteristics of oral squamous cell carcinomas.

Huang TT, Gonzales CB, Gu F, Hsu YT, Jadhav RR, Wang CM, Redding SW, Tseng CE, Lee CC, Thompson IM, Chen HR, Huang TH, Kirma NB.

Carcinogenesis. 2013 Aug;34(8):1717-27. doi: 10.1093/carcin/bgt112. Epub 2013 Apr 8.

17.

Raf-1, a potential therapeutic target, mediates early steps in endometriosis lesion development by endometrial epithelial and stromal cells.

De La Garza EM, Binkley PA, Ganapathy M, Krishnegowda NK, Tekmal RR, Schenken RS, Kirma NB.

Endocrinology. 2012 Aug;153(8):3911-21. doi: 10.1210/en.2011-1879. Epub 2012 May 22.

PMID:
22619359
18.

Increased expression of macrophage colony-stimulating factor and its receptor in patients with endometriosis.

Budrys NM, Nair HB, Liu YG, Kirma NB, Binkley PA, Kumar S, Schenken RS, Tekmal RR.

Fertil Steril. 2012 May;97(5):1129-35.e1. doi: 10.1016/j.fertnstert.2012.02.007. Epub 2012 Feb 24.

19.

Transgenic mouse models of hormonal mammary carcinogenesis: advantages and limitations.

Kirma NB, Tekmal RR.

J Steroid Biochem Mol Biol. 2012 Sep;131(3-5):76-82. doi: 10.1016/j.jsbmb.2011.11.005. Epub 2011 Nov 17. Review.

PMID:
22119744
20.

Estrogen receptor-beta mediates the protective effects of aromatase induction in the MMTV-Her-2/neu x aromatase double transgenic mice.

Nair HB, Perla RP, Kirma NB, Krishnegowda NK, Ganapathy M, Rajhans R, Nair SS, Saikumar P, Vadlamudi RK, Tekmal RR.

Horm Cancer. 2012 Apr;3(1-2):26-36. doi: 10.1007/s12672-011-0083-5.

PMID:
22006184

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