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Pratol, an O-Methylated Flavone, Induces Melanogenesis in B16F10 Melanoma Cells via p-p38 and p-JNK Upregulation.

Chung YC, Kim S, Kim JH, Lee GS, Lee JN, Lee NH, Hyun CG.

Molecules. 2017 Oct 11;22(10). pii: E1704. doi: 10.3390/molecules22101704.


Geraniin Promotes Recovery of Hematopoietic Cells after Radiation Injury.

Bing SJ, Cho J, Kim A, Herath KHINM, Ahn G, Lee NH, Park JW, Jee Y.

Am J Chin Med. 2017;45(5):1003-1016. doi: 10.1142/S0192415X17500537. Epub 2017 Jun 28.


A randomized clinical trial comparing long-term clopidogrel vs aspirin monotherapy beyond dual antiplatelet therapy after drug-eluting coronary stent implantation: Design and rationale of the Harmonizing Optimal Strategy for Treatment of coronary artery stenosis-Extended Antiplatelet Monotherapy (HOST-EXAM) trial.

Lee H, Koo BK, Park KW, Shin ES, Lim SW, Rha SW, Bae JW, Jeon DW, Oh SK, Hur SH, Kim BS, Lee JH, Park TH, Lee NH, Kim HS; HOST-EXAM investigators.

Am Heart J. 2017 Mar;185:17-25. doi: 10.1016/j.ahj.2016.12.001. Epub 2016 Dec 9.


3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways.

Ali I, Manzoor Z, Koo JE, Kim JE, Byeon SH, Yoo ES, Kang HK, Hyun JW, Lee NH, Koh YS.

Pharm Biol. 2017 Dec;55(1):435-440.


Beetroot (Beta vulgaris) rescues mice from γ-ray irradiation by accelerating hematopoiesis and curtailing immunosuppression.

Cho J, Bing SJ, Kim A, Lee NH, Byeon SH, Kim GO, Jee Y.

Pharm Biol. 2017 Dec;55(1):306-319.


Blood Pressure and Cholesterol-lowering Efficacy of a Fixed-dose Combination With Irbesartan and Atorvastatin in Patients With Hypertension and Hypercholesterolemia: A Randomized, Double-blind, Factorial, Multicenter Phase III Study.

Kim SH, Jo SH, Lee SC, Lee SY, Yoon MH, Lee HL, Lee NH, Ha JW, Lee NH, Kim DW, Han GR, Hyon MS, Cho DG, Park CG, Kim YD, Ryu GH, Kim CH, Kim KS, Chung MH, Chae SC, Seung KB, Oh BH.

Clin Ther. 2016 Oct;38(10):2171-2184. doi: 10.1016/j.clinthera.2016.09.005. Epub 2016 Oct 12.


Anti-wrinkle effects of Sargassum muticum ethyl acetate fraction on ultraviolet B-irradiated hairless mouse skin and mechanistic evaluation in the human HaCaT keratinocyte cell line.

Song JH, Piao MJ, Han X, Kang KA, Kang HK, Yoon WJ, Ko MH, Lee NH, Lee MY, Chae S, Hyun JW.

Mol Med Rep. 2016 Oct;14(4):2937-44. doi: 10.3892/mmr.2016.5655. Epub 2016 Aug 19.


Promotion Effect of Apo-9'-fucoxanthinone from Sargassum muticum on Hair Growth via the Activation of Wnt/β-Catenin and VEGF-R2.

Kang JI, Yoo ES, Hyun JW, Koh YS, Lee NH, Ko MH, Ko CS, Kang HK.

Biol Pharm Bull. 2016;39(8):1273-83. doi: 10.1248/bpb.b16-00024.


Comparative Depigmentation Effects of Resveratrol and Its Two Methyl Analogues in α-Melanocyte Stimulating Hormone-Triggered B16/F10 Murine Melanoma Cells.

Yoon HS, Hyun CG, Lee NH, Park SS, Shin DB.

Prev Nutr Food Sci. 2016 Jun;21(2):155-9. doi: 10.3746/pnf.2016.21.2.155. Epub 2016 Jun 30.


4-Hydroxy-2,3-Dimethyl-2-Nonen-4-Olide Has an Inhibitory Effect on Pro-Inflammatory Cytokine Production in CpG-Stimulated Bone Marrow-Derived Dendritic Cells.

Manzoor Z, Koo JE, Ali I, Kim JE, Byeon SH, Yoo ES, Kang HK, Hyun JW, Lee NH, Koh YS.

Mar Drugs. 2016 May 4;14(5). pii: E88. doi: 10.3390/md14050088.


External Application of Apo-9'-fucoxanthinone, Isolated from Sargassum muticum, Suppresses Inflammatory Responses in a Mouse Model of Atopic Dermatitis.

Han SC, Kang NJ, Yoon WJ, Kim S, Na MC, Koh YS, Hyun JW, Lee NH, Ko MH, Kang HK, Yoo ES.

Toxicol Res. 2016 Apr;32(2):109-14. doi: 10.5487/TR.2016.32.2.109. Epub 2016 Apr 30.


Photo-protective effect of sargachromenol against UVB radiation-induced damage through modulating cellular antioxidant systems and apoptosis in human keratinocytes.

Fernando PM, Piao MJ, Hewage SR, Kang HK, Yoo ES, Koh YS, Ko MH, Ko CS, Byeon SH, Mun SR, Lee NH, Hyun JW.

Environ Toxicol Pharmacol. 2016 Apr;43:112-9. doi: 10.1016/j.etap.2016.02.012. Epub 2016 Feb 23.


Efficacy and Safety of DP-R202 in Patients with Chronic Artery Occlusive Disease: Multicenter Randomized Double-blind Active-controlled Parallel Group Phase III Clinical Study.

Lee HC, Lee SR, Han KR, Yu CW, Park CG, Ahn YK, Jin HY, Kim DW, Cho DK, Choi S, Kim SH, Chang KY, Lee S, Pyun W, Lee NH, Kang W, Hong BK, Cho BR, Chae IH, Shin JH, Chun K, Kim DI, Lee JW, Kim YJ, Choi D.

Clin Ther. 2016 Mar;38(3):557-73. doi: 10.1016/j.clinthera.2016.01.009. Epub 2016 Feb 5.


Anti-inflammatory effects of isoketocharbroic acid from brown alga, Sargassum micracanthum.

Ham YM, Yoon WJ, Lee WJ, Kim SC, Baik JS, Kim JH, Lee GS, Lee NH, Hyun CG.

EXCLI J. 2015 Oct 15;14:1116-21. doi: 10.17179/excli2015-555. eCollection 2015.


Effect of Intravascular Ultrasound-Guided vs Angiography-Guided Everolimus-Eluting Stent Implantation: The IVUS-XPL Randomized Clinical Trial.

Hong SJ, Kim BK, Shin DH, Nam CM, Kim JS, Ko YG, Choi D, Kang TS, Kang WC, Her AY, Kim YH, Hur SH, Hong BK, Kwon H, Jang Y, Hong MK; IVUS-XPL Investigators.

JAMA. 2015 Nov 24;314(20):2155-63. doi: 10.1001/jama.2015.15454. Erratum in: JAMA. 2016 Feb 2;315(5):518. Kim, Yonghoon [corrected to Kim, Yong Hoon].


Diphlorethohydroxycarmalol Suppresses Ultraviolet B-Induced Matrix Metalloproteinases via Inhibition of JNK and ERK Signaling in Human Keratinocytes.

Piao MJ, Susara Ruwan Kumara MH, Kim KC, Kang KA, Kang HK, Lee NH, Hyun JW.

Biomol Ther (Seoul). 2015 Nov;23(6):557-63. doi: 10.4062/biomolther.2015.054. Epub 2015 Nov 1.


Evaluation of the Efficacy and Safety of the Lercanidipine/Valsartan Combination in Korean Patients With Essential Hypertension Not Adequately Controlled With Lercanidipine Monotherapy: A Randomized, Multicenter, Parallel Design, Phase III Clinical Trial.

Na SH, Lee HY, Hong Baek S, Jeon HK, Kang JH, Kim YN, Park CG, Ryu JK, Rhee MY, Kim MH, Hong TJ, Choi DJ, Cho SW, Cha DH, Jeon ES, Kim JJ, Shin JH, Park SH, Lee SH, John SH, Shin ES, Kim NH, Lee SY, Kwan J, Jeong MH, Kim SW, Jeong JO, Kim DW, Lee NH, Park WJ, Ahn JC, Won KH, Uk Lee S, Cho JH, Kim SK, Ahn T, Hong S, Yoo SY, Kim SY, Kim BS, Juhn JH, Kim SY, Lee YJ, Oh BH.

Clin Ther. 2015 Aug;37(8):1726-39. doi: 10.1016/j.clinthera.2015.05.512. Epub 2015 Jul 8.


Clinical Impact of Intravascular Ultrasound-Guided Chronic Total Occlusion Intervention With Zotarolimus-Eluting Versus Biolimus-Eluting Stent Implantation: Randomized Study.

Kim BK, Shin DH, Hong MK, Park HS, Rha SW, Mintz GS, Kim JS, Kim JS, Lee SJ, Kim HY, Hong BK, Kang WC, Choi JH, Jang Y; CTO-IVUS Study Investigators.

Circ Cardiovasc Interv. 2015 Jul;8(7):e002592. doi: 10.1161/CIRCINTERVENTIONS.115.002592.


Melanogenesis inhibitory activity of Korean Undaria pinnatifida in mouse B16 melanoma cells.

Kim MJ, Kim DS, Yoon HS, Lee WJ, Lee NH, Hyun CG.

Interdiscip Toxicol. 2014 Jun;7(2):89-92. doi: 10.2478/intox-2014-0012. Epub 2014 Nov 15.

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